| Agent Name |
Diacetone alcohol |
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| Alternative Name |
4-Hydroxy-4-methyl-2-pentanone |
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| CAS Number |
123-42-2 |
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| Formula |
C6-H12-O2 |
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| Major Category |
Solvents |
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| Synonyms |
2-Methyl-2-pentanol-4-one; 2-Pentanone, 4-hydroxy-4-methyl-; 4-Hydroxy-2-keto-4-methylpentane; 4-Hydroxy-4-methyl pentan-2-one; 4-Hydroxy-4-methylpentanone-2; Acetonyldimethylcarbinol; Diacetone; Diacetone alcohol; Diacetonyl alcohol; Diketone alcohol; Dimethyl acetonyl carbinol; Pyranton; Pyranton A; Tyranton; [ChemIDplus] UN1148 |
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| Category |
Ketones |
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| Description |
Colorless liquid with a faint, minty odor; [NIOSH] |
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| Sources/Uses |
Used in antifreeze and brake fluids; also used as a solvent to make nitrocellulose, cellulose acetate, celluloid, pigments, waxes, and oils; [ACGIH] |
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| Comments |
Narcosis induced in animal inhalation studies; [ACGIH] |
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| Exposure Assessment |
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| Skin Designation (ACGIH) |
No |
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| TLV (ACGIH) |
50 ppm |
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| PEL (OSHA) |
50 ppm |
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| MAK |
20 ppm |
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| IDLH (NIOSH) |
1800 ppm |
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| Excerpts from Documentation for IDLHs |
It has been reported that eye irritation appeared in volunteers exposed for 15 minutes at 100 ppm [Silverman et al. 1946]. |
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| Vapor Pressure |
1.71 mm Hg |
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| Odor Threshold Low |
0.27 ppm |
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| Odor Threshold High |
1.1 ppm |
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| Lethal Concentration |
LCLo (rats) = 1,000 ppm/4h |
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| Explanatory Notes |
IDLH = 10% LEL (lower explosive limit); Detection odor threshold from AIHA (mean = 0.27 ppm); Flash point = 66 deg C; |
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| Flammability (NFPA) |
2: high ambient temperature required |
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| Adverse Effects |
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| Neurotoxin |
CNS Solvent Syndrome |
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| Links to Other NLM Databases |
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| Health Studies |
Human Health Effects from Hazardous Substances Data Bank: 4-HYDROXY-4-METHYL-2-PENTANONE
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