Type 1 Diabetes (T1D) Special Statutory Funding Program
Research Consortia and Clinical Trials Networks
Clinical Research
Clinical Islet Transplantation Consortium (CIT)
The purpose of this consortium is to develop and implement a program of single- and/or multi-center clinical studies, accompanied by mechanistic studies, in islet transplantation with or without accompanying kidney transplantation, for the treatment of type 1 diabetes.
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Diabetes Prevention Trial-Type 1 (DPT-1)
The Diabetes Prevention Trial-Type 1 (DPT-1) consisted of two clinical trials that sought to delay or prevent type 1 diabetes. One DPT-1 trial tested whether low-dose insulin injections could prevent or delay the development of type 1 diabetes in people at high risk for developing type 1 diabetes within 5 years. The other was an oral insulin trial that sought to prevent type 1 diabetes in people with a moderate risk for developing diabetes.
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Diabetes Research in Children Network (DirectNet)
The mission of DirecNet is to investigate the potential use of glucose monitoring technology and its impact on the management of type 1 diabetes in children.
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Diabetic Retinopathy Clinical Research Network (DRCR.net)
The mission of DRCR.net is to facilitate the conduct of multi-center clinical research of diabetic retinopathy, diabetic macular edema (DME), and associated conditions.
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Epidemiology of Diabetes Interventions and Complications (EDIC)
The aim of EDIC is to study the clinical course and risk factors associated with the long-term complications of type 1 diabetes, using the cohort of the Diabetes Control and Complications Trial (DCCT).
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Family Investigation of Nephropathy and Diabetes (FIND)
The FIND consortium is carrying out studies to elucidate the genetic susceptibility to kidney disease in patients, especially those with diabetes mellitus, as well as genetic susceptibility to retinopathy in diabetic patients.
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Genetics of Kidneys in Diabetes (GoKinD)
The fundamental aim of GoKinD is to facilitate investigator-driven research into the genetic basis of diabetic nephropathy by collecting, storing, and distributing genetic samples from cases and controls of type 1 diabetes and diabetic nephropathy.
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Immune Tolerance Network (ITN)
The ITN is an international consortium of scientists and physicians dedicated to the clinical evaluation of novel tolerogenic approaches for the treatment of autoimmune diseases, asthma and allergic diseases, and the prevention of graft rejection. More Information
The Environmental Determinants of Diabetes in the Young (TEDDY)
The primary objective(s) of this multi-center, multi-national, epidemiological study is the identification of infectious agents, dietary factors, or other environmental exposures that are associated with increased risk of autoimmunity and type 1 diabetes.
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Trial to Reduce IDDM in the Genetically at Risk (TRIGR)
The overall primary objective of this multi-center, international study is to determine whether weaning to a casein hydrolysate formula during the first 6-8 months of life in place of cow's milk based formula reduces the incidence of autoimmunity and type 1 diabetes in genetically susceptible newborn infants.
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Type 1 Diabetes Genetics Consortium (T1DGC)
T1DGC was established with the primary goal of organizing international efforts to identify genes that determine an individual's risk of type 1 diabetes.
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Type 1 Diabetes TrialNet (TrialNet)
TrialNet is an international network of investigators, clinical centers, and core support facilities whose aim is to recruit patients and support studies that will result in an improved understanding of type 1 diabetes disease development and will test strategies for its prevention.
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Last Updated: June 30, 2008
