Cooperative Study Group for Autoimmune Disease Prevention (Prevention Centers)
The mission of the Prevention Centers is to engage in scientific discovery which significantly advances knowledge for the prevention and regulation of autoimmune disease.
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Diabetes Prevention Trial-Type 1 (DPT-1)
The Diabetes Prevention Trial-Type 1 (DPT-1) consisted of two clinical trials that sought to delay or prevent type 1 diabetes. One DPT-1 trial tested whether low-dose insulin injections could prevent or delay the development of type 1 diabetes in people at high risk for developing type 1 diabetes within 5 years. The other was an oral insulin trial that sought to prevent type 1 diabetes in people with a moderate risk for developing diabetes.
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Immune Tolerance Network (ITN)
The ITN is an international consortium of scientists and physicians dedicated to the clinical evaluation of novel tolerogenic approaches for the treatment of autoimmune diseases, asthma and allergic diseases, and the prevention of graft rejection. More Information
Trial to Reduce IDDM in the Genetically at Risk (TRIGR)
The overall primary objective of this multi-center, international study is to determine whether weaning to a casein hydrolysate formula during the first 6-8 months of life in place of cow's milk based formula reduces the incidence of autoimmunity and type 1 diabetes in genetically susceptible newborn infants.
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Type 1 Diabetes TrialNet (TrialNet)
TrialNet is an international network of investigators, clinical centers, and core support facilities whose aim is to recruit patients and support studies that will result in an improved understanding of type 1 diabetes disease development and will test strategies for its prevention.
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