Protocol Number: 97-H-0130

Title:

Collection of Blood and Bone Marrow from Normal Volunteers and Patients for Research Purposes

Number:

97-H-0130

Summary:

This study is designed to provide bone marrow and/or blood cells for other research studies. Patients participating in this study will be asked to provide small amounts of medical information and undergo a limited physical examination designed to detect the presence of any obvious blood disease. A blood and bone marrow sample will be obtained to verify that the patient has normal blood cell production.

Researchers plan to obtain bone marrow samples to be used in laboratory studies directed toward understanding the formation of blood cells. Bone marrow samples will be taken from the hip bone of patients and normal volunteers.

These samples are valuable to many research studies within the Hematology Branch of the National Heart, Lung, and Blood Institute, including studies of normal and abnormal production of blood cells, the viral causes of blood diseases, and the role of the immune system in bone marrow failure and related conditions.

Sponsoring Institute:

National Heart, Lung and Blood Institute (NHLBI)

Recruitment Detail

Type: No longer recruiting/follow-up only

Gender: Male & Female

Referral Letter Required: No

Population Exclusion(s): None

Eligibility Criteria: This study is not currently recruiting new subjects. If you have questions about participating in a study, please contact the Patient Recruitment and Public Liaison Office, CC.

Special Instructions:

This protocol includes:

1. Bone Marrow Aspiration: Aspirates are obtained from the posterior iliac spine.

2. Bone Marrow Biopsy: The bone marrow biopsy core is obtained with a Jamshidi needle using standard clinical techniques.

3. Peripheral Blood: From 20-100 ml of blood is obtained by venipuncture from a peripheral vein.

Keyword(s):

Bone Marrow

Hematopoiesis

DNA

RNA

Viruses

Recruitment Keyword(s):

Normal Volunteer

Aplastic Anemia

Myelodysplasia

Fanconi's Anemia

Single Lineage Cytopenia

Condition(s):

Aplastic Anemia

Fanconi's Anemia

Healthy

Hematologic Disease

Myelodysplastic Syndrome

Investigational Drug(s):

None

Investigational Device(s):

None

Interventions:

None

Supporting Site:

National Heart, Lung and Blood Institute

Contact(s):

This study is not currently recruiting new subjects. If you have questions about participating in a study, please contact the Patient Recruitment and Public Liaison Office, CC.

Citation(s): Not Provided

• Questions about participating in a study, please contact the Patient Recruitment and Public Liaison Office, CC.
• Technical questions regarding the Clinical Center web site, please contact the Department Clinical Research Informatics, CC.

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