Protocol Number: 00-CH-0127

Title:

Evaluation of Patients with Endocrine-Related Conditions

Number:

00-CH-0127

Summary:

This study will evaluate patients with a variety of endocrine disorders in order to 1) learn more about conditions that affect the endocrine glands (glands that secrete hormones) and 2) to train physicians in endocrinology.

Patients of all ages with endocrine-related conditions may be eligible for evaluation under this protocol. Those enrolled may be required to provide blood, saliva, urine or stool samples, and to undergo ultrasound examination of the thyroid gland, ovaries or testes, adrenal glands or other parts of the body. Laboratory or X-ray studies may be done for diagnostic or treatment purposes. In some cases, patients will receive medical or surgical treatment for their disorder. Patients and family members of patients with a hereditary disorder may be asked to provide a blood sample for genetic analysis.

Sponsoring Institute:

National Institute of Child Health and Human Development (NICHD)

Recruitment Detail

Type: Participants currently recruited/enrolled

Gender: Male & Female

Referral Letter Required: No

Population Exclusion(s): None

Eligibility Criteria:

INCLUSION CRITERIA:

Patients of all ages with endocrine-related conditions will be eligible for this protocol.

EXCLUSION CRITERIA:

Unstable patients and patients with severe organ failure that may affect/limit the endocrine work-up and exhaust Clinical Center and/or NICHD resources will be excluded.

Hematologic abnormalities: platelets less than 100,000 cells/mm(3), hemoglobin less than 10 mg/dl and/or WBC less than 3,000 cells/mm(3).

Cardiovascular disorders: Clinical evidence of congestive heart failure, unstable angina.

Hepatic/Renal Dysfunction: Severe hepatic insufficiency (SGOT, SGPT, alkaline phosphatase, total bilirubin) greater than 200% of the upper limit of normal); serum creatinine greater than 2.0 mg/dl.

Respiratory distress: Ventilator-dependent patients.

Advanced and/or multiple non-endocrine disorders.

Special Instructions:

Currently Not Provided

Keywords:

Hormones

Training

Recruitment Keyword(s):

Endocrine Related Conditions

Endocrine Dysfunction

Early Pubertal Development

Condition(s):

Endocrine Disease

Glucose Intolerance

Hyperinsulinemia

Impaired Glucose Tolerance

Non Insulin Dependent Diabetes Mellitus

Obesity

Type II Diabetes Mellitus

Investigational Drug(s):

None

Investigational Device(s):

None

Intervention(s):

None

Supporting Site:

National Institute of Child Health and Human Development

Contact(s):

Patient Recruitment and Public Liaison Office
Building 61
10 Cloister Court
Bethesda, Maryland 20892-4754
Toll Free: 1-800-411-1222
TTY: 301-594-9774 (local),1-866-411-1010 (toll free)
Fax: 301-480-9793

Electronic Mail:prpl@mail.cc.nih.gov

Citation(s): Not Provided

• Questions about participating in a study, please contact the Patient Recruitment and Public Liaison Office, CC.
• Technical questions regarding the Clinical Center web site, please contact the Department of Clinical Research Informatics, CC.

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National Institutes of Health Clinical Center Bethesda, Maryland 20892. Last update: 01/30/2009