INCLUSION CRITERIA:
Patients who are evaluated by the Pediatric Oncology Branch and are:
Children with cancer (or a precancer syndrome), between the age(s) of 3 months to 40 years.
Patients between the ages of 30 and 40 years may be evaluated on this protocol if their cancer (or precancer syndrome) is of specific interest to the Pediatric Oncology Branch.
Patients with cancer (or a precancer syndrome), who present with disease manifestations of special interest to Pediatric Oncology Branch investigators, including but not limited to, lymphoma, brain tumors, Ewings sarcoma, leukemia, neuroectodermal tumors, osteosarcoma, rhabdomysarcoma.
If indicated, availability of a parent or legal guardian to give informed consent.
Patients, and, when indicated, parent or legal guardian who are deemed sufficiently reliable to return for recommended follow-up visits.
Patients greater than or equal to 18 years of age must be able to give informed consent.
EXCLUSION CRITERIA:
Patients younger than 3 months of age.