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Computational Bioscience and Engineering Laboratory
Office of the Chief (OC)
Acting Chief: Benes L. Trus, Ph.D.

The Office of the Chief provides overall CBEL management and planning, including laboratory, administrative and financial functions. It coordinates the establishment of new laboratory activities and the work of the sections and groups to encourage and ensure appropriate cooperation and integration of effort. It also coordinates CBEL work with other parts of CIT and the NIH ICs, as well as other government agencies and research institutions.
Bioinformatics and Molecular Analysis Section (BIMAS)
Chief: John Powell.

BIMAS develops computational methods for the analysis of data related to molecular biology and genetics; and provides bioinformatics guidance, support, and resources for the collection, management, and display of biological sequence and genomic information, for NIH scientists involved in genomics and genetic analysis. Research and development projects include:
  • Protein and Nucleic Acid Sequence Analysis
  • Genomic Analysis Support
  • cDNA Microarray Gene Expression Analysis


Signal Processing and Instrumentation Section (SPIS)
Chief: Tom Pohida

SPIS provides electrical, electronic, electro-optical, and computer engineering support to clinical and biomedical research projects involving advanced real-time signal transduction, signal processing, and control. Research and development projects include:
  • cDNA Microarray
  • Laser Capture Microdissection
  • High-Speed Optical Multi-channel Analyzer
  • Electron Paramagnetic Resonance Spectrometer/Imager
  • Chromosome Microdissection System
  • Tissue Microarray System
  • MRI Adaptive Speech/Noise Processing System


Biomedical Imaging and Visualization Section (BIVS)
Chief: Kenneth M. Kempner

TAIS explores and develops image management, communication, and processing technologies in support of clinical image acquisition, transmission, and interpretation. Major projects involve the adaptation and utilization of telemedicine and collaborative technologies to support long distance medical and scientific work between NIH and other institutions. Also under development are new image processing and computer modeling techniques for NIH scientists using MRI. Research and development projects include:
  • TELESYNERGY Medical Consultation WorkStation System
  • Medical Image Display Systems
  • High-speed Image Communication Networks
  • Medical Haptics
  • Diffusion MR Image Processing and Data Acquisition



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