Dystonia Research Study
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Neurophysiology of Task-Specificity in Writer's Cramp
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People with focal hand dystonia/writer's cramp over the age of 18 are needed for this study to understand why writing is impaired in people with focal hand dystonia. This study will use transcranial magnetic stimulation (TMS) and surface recording of muscle activity.
For the TMS procedure, subjects are seated in a comfortable chair with their hands placed on a pillow on their lap. An insulated wire coil is placed on the scalp. A brief electrical current is passed through the coil, creating a magnetic pulse that stimulates the brain.
The study involves one to two outpatient visits lasting up to 4 hours each to the NIH Clinical Center in Bethesda, MD. On one visit, TMS will be applied during different kinds of movement. On the other visit, TMS will be applied while the subject watches a computer screen and presses a button with their hand or foot.
There is no cost for participation. Travel to and from NIH within the USA is provided for participants.
For more information or if you're interested, please contact:
Dr. Sarah Pirio Richardson
Clinical Fellow
Human Motor Control Section
National Institutes of Health
National Institute of Neurological Disorders & Stroke
10 Center Drive Bldg 10 Room 5N226
Bethesda, Maryland 20892
Phone: (301) 402-3499
Fax: (301) 480-2286
richardsa@ninds.nih.gov
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Dystonia Research Study
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Trial of amlodipine for patients with cervical dystonia receiving botulinum toxin injections
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We are looking for people with cervical dystonia or focal hand dystonia (writer's cramp) who are receiving botulinum toxin injections, but who improve less than 75% with injections or who have benefit lasting less than 2 months. We are trying to find out if amlodipine, a medication used for the treatment of high blood pressure, can improve the effect botulinum toxin injections for dystonia.
The study involveds approximately 10 outpatient visits lasting about 1 hour each to the NIH Clinical Center in Bethesda, MD over a 9 month period. 3 botulinum toxin injections will be provided during study participation as well as the study medication.
There is no cost for participation. Travel to and from NIH within the USA is provided for participants.
For more information, please contact:
Dr. Barbara Karp
Building 10; Room 6-5733
NINDS, NIH
Bethesda, MD 20892
Phone: 301-496-0150
Fax: 301-480-2973
Or Ms. Elizabeth Bartrum, CRNP
e-mail: bartrume@ninds.nih.gov
Please contact: < for further information.
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Disease and Treatment Information |
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