Diabetes: Control - Slide 15

EDIC Findings: Intensive Therapy and Diabetes Complications

• Participants continue to benefit years later from period of intense glucose control

• Years after intensive therapy:

  • Lasting benefits for eye, nerve, and kidney disease

  • Reduces CVD events by more than half

DCCT/EDIC N Engl J Med 2005: 353:2643-2653.

Note:

EDIC findings are compelling:

• More than a decade after the DCCT was concluded, study participants are still benefiting from benefiting from their approximately 6.5 years of intense glucose control.

• Lasting benefits for eye, nerve, and kidney disease

• Intensively treated patients had less than half the number of cardiovascular (CVD) events than the conventionally treated group.

• Such events included heart attacks, stroke, angina, and coronary artery disease requiring angioplasty of coronary bypass surgery.

Reference

The DCCT/EDIC Study Research Group. New England Journal of Medicine, 353:2643-2653, December 22, 2005.

Revised November 2008