Diabetes: Control - Slide 12

UKPDS Findings

• Mirrored the findings of DCCT in people with type 2 diabetes—better glucose control reduced development of microvascular complications

• Demonstrated the need for management of high blood pressure and cholesterol as well as blood glucose levels (the ABCs of diabetes)

UKPDS. BMJ. 2000; 321:405-412.

Note:

• UKPDS mirrored the findings of the DCCT in people with type 2 diabetes – also showing that tighter blood glucose control reduced the development of diabetes complications.

• The UKPDS also demonstrated the need for management of high blood pressure (hypertension) and cholesterol (dislipidemia) in addition to blood glucose levels.

• So, controlling the ABCs of diabetes (A1C, Blood Pressure, and Cholesterol) can reduce the development of diabetes complications.

Reference

Stratton IM, Et al. Association of glycemia with macrovascular and microvascular complications of type 2 diabetes (UKPDS 35): Prospective observational study. BMJ. 2000; 321:405-412.

Revised November 2008