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Chronic fatigue syndrome: what role does the autonomic nervous system play in the pathophysiology of this complex illness?

Gerrity TR, Bates J, Bell DS, Chrousos G, Furst G, Hedrick T, Hurwitz B, Kula RW, Levine SM, Moore RC, Schondorf R.
Chronic fatigue syndrome: what role does the autonomic nervous system play in the pathophysiology of this complex illness?
NeuroImmunoModulation 10:134-141, 2002.

Summary

CDC has cosponsored three CFS Assessment Symposia Series workshops with the CIFDS Association of America. The Symposia addressed the role of the autonomic nervous system in the pathophysiology of CFS, neuroendocrine aspects of CFS, and immunological aspects of CFS. This publication is the report from the first Symposium on the role of the autonomic nervous system in CFS.

Abstract

Chronic fatigue syndrome (CFS) is a serious health concern affecting over 800,000 Americans of all ages, races, and socioeconomic groups and both genders. The etiology and pathophysiology of CFS are unknown, yet studies have suggested an involvement of the autonomic nervous system (ANS). A symposium was organized in December 2000 to explore the possibility of an association between ANS dysfunction and CFS, with special emphasis on the interactions between ANS dysfunction and other abnormalities noted in the immune and endocrine systems of individuals with CFS. This paper represents the consensus of the panel of experts who participated in this meeting.

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