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| Active Bacterial Core Surveillance |
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| Home > Overview, Team |
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Overview
Background | CDC Participants | Surveillance Areas
| Background |
Active Bacterial Core surveillance (ABCs) is a core component of CDC’s Emerging Infections Programs Network (EIP), a collaboration between CDC, state health departments, and universities. ABCs is an active laboratory- and population-based surveillance system for invasive bacterial pathogens of public health importance. For each case of invasive disease in the surveillance population, a case report with basic demographic information is completed and bacterial isolates are sent to CDC and other reference laboratories for additional laboratory evaluation. ABCs also provides an infrastructure for further public health research, including special studies aiming at identifying risk factors for disease, post-licensure evaluation of vaccine efficacy and monitoring effectiveness of prevention policies.
ABCs was initially established in four states in 1995. It currently operates among 10 EIP sites across the United States , representing a population of over 38 million persons. At this time, ABCs conducts surveillance for six pathogens: group A and group B streptococcus (GAS, GBS), Haemophilus influenzae, Neisseria meningitidis, Streptococcus pneumoniae, and methicillin-resistant Staphylococcus aureus (MRSA) .
ABCs data have been used to track disease trends, including the decline in pneumococcal disease following the introduction of the pediatric pneumococcal conjugate vaccine and the emergence of serogroup Y meningococcal disease. ABCs has also contributed to public health policy by providing information which formed the basis of revised CDC guidelines recommending the use of universal screening of pregnant women to prevent early onset GBS infections and the prevention of GAS infections among household contacts of persons with invasive disease and among postpartum and post-surgical patients. A program to assist state and local health departments with surveillance for MRSA and drug-resistant Streptococcus pneumoniae has been developed, based primarily on lessons learned from ABCs.
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| CDC Participants |
Centers for Disease Control and Prevention,
National Center for Infectious and Respiratory Diseases (NCIRD ) (proposed)
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Core ABCs activities, including data collection, management and principal analyses, result from the collaboration among four branches at CDC: Respiratory Diseases Branch, Meningitis and Special Pathogens Branch, Biostatistics and Information Management Branch and Health Outcomes Branch. Pathogen-specific analyses are undertaken by personnel in each branch as outlined below:
Respiratory Diseases Branch (RDB),
Division of Bacterial Diseases (DBD) (proposed) |
RDB is responsible for designing and conducting epidemiologic studies, isolate tracking and additional laboratory characterization of the following ABCs organisms: group A streptococcus, group B streptococcus, and Streptococcus pneumoniae.
Meningitis and Vaccine Preventable Diseases Branch (MVPDB) (proposed) ,
Division of Bacterial Diseases (DBD) (proposed) |
MVPDB is responsible for designing and conducting epidemiologic studies, isolate tracking and additional laboratory characterization of the following organisms: Haemophilus influenzae and Neisseria meningitidis.
Biostatistics Office (BSO),
Division of Bacterial Diseases (DBD) (proposed) |
BIMB is responsible for data management, statistical analysis, programming support, and creation of surveillance reports for all ABCs pathogens.
Health Outcomes Branch (HOB),
Division of Healthcare Quality Promotion (DHQP) |
HOB is responsible for designing and conducting epidemiologic studies, isolate tracking and additional laboratory characterization of methicillin-resistant Staphylococcus aureus infections.
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| Surveillance Areas |
Emerging Infections Programs (EIP)/
Active Bacterial Core surveillance (ABCs)
Site |
State Health Dept |
Partner(s) |
CA |
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Public Health Foundation Enterprises, Inc.
University of CA at Berkeley |
CO |
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Dept of Preventive Medicine, University of Colorado Health Sciences Center |
CT |
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Yale University School of Medicine |
GA |
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Emory University Dept of Medicine, Division of Infectious Diseases
Atlanta VA Medical Center |
MD |
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Johns Hopkins Bloomberg School of Public Health |
MN |
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Association for Professionals in Infection Control and Epidemiology, Inc. (APIC) |
NM |
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University of New Mexico Health Sciences Center |
NY |
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Monroe County Health Dept
University of Rochester School of Medicine and Dentistry |
OR |
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Oregon Health and Science University
OSW-APIC |
TN |
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Vanderbilt Medical Center |
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Date: January 29, 2007
Content source: National Center for Immunization and Respiratory Diseases / Division of Bacterial Diseases |
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