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Style Guide
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Table of Contents

A–Z Index

General Information

  •

Authorship

  •

Copyright

  •

Instructions to Authors

  •

Checklist
Specific Style Issues

  •

Abbreviations and Acronyms

  •

Affiliations

  •

Appendixes

  •

Capitalization

  •

Geographic Designations

  •

Numbers

  •

Preferred Usage

  •

Punctuation

  •

References

  •

Scientific Nomenclature

  •

Spelling

  •

Tables and Figures

  •

Units of Measure

  •

Verbs

Other Resources

  •

Comprehensive Style Guides & Other Resources
  •
Internet Resources

 


 
Style Guide for Authors and Editors (page 3 of 6)


Specific Style Issues

(Note: parenthetical acronyms refer to style guides listed in Other Resources )

Abbreviations and Acronyms

A sentence can begin with an abbreviation. It cannot begin with a figure or symbol.

WBC count was . . .
Alpha (not the symbol) particles are. . .(CMS)

The article "a" or "an" should match the sound of the abbreviation or acronym, not the word for which it stands. (AMA)

an HMO report, but a health maintenance organization

However, articles are often omitted in front of abbreviations.

CDC, not the CDC

Avoid too many abbreviations. Use standard abbreviations only; do not make up abbreviations. Spell out on first mention and use only if acronym occurs at least five times.

If an organization's name has been translated into English, the organization's original acronym can be used on the second use of the organization's name even if the organization is not mentioned five times.

Abstracts may contain abbreviations after a single mention. (ASM)

See ASM for complete list of abbreviations that need not be introduced, for example:

AIDS
bp
DNA
EDTA
HIV
RNA

The following are abbreviations that must be introduced but are allowed after initial mention (see ASM for complete list):

AZT
CFU
CNS
CSF
ECG, not EKG
ELISA
Government agencies (PAHO, WHO, CDC, WTO, FAO, USDA, FDA, APHIS, EPA)
HACCP
HPS
HUS
IFA (immunofluorescence assay)
IgG, IgM
IL
MDRTB (not MDR-TB)
PCR
RT-PCR
TB
VRE

Dates – Spell out months in text. In tables, figures (AMA), and references (UR), abbreviate months using the first three letters.

SI Units

Use SI units for units of measure (AMA), for example:

centimeter cm
cubic millimeter mm3
dalton Da
deciliter dL
gram g
kilodalton kDa
kilogram kg
liter L
meter m
microgram µg
microliter µL
milligram mg
milliliter mL
millimeter mm

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Affiliations

Use the following symbols, in the order shown, for affiliations.

*


§

#

If there are more than 6 affiliations, use double (e.g., **, ††, etc.) symbols.

Appendixes

Generally, avoid using appendixes; however sometimes they serve a useful purpose for data that cannot be presented easily as a table or a figure. In these cases, appendixes are cited in the text as a table or figure would be cited. (e.g., Appendix 1) and are usually placed at the end of an article, before the references.

If the appendix cites references but contains no figures or tables, it should be placed before the reference list for the article, and the references should be sequential with those in the text.

If the appendix contains figures or tables, but cites no references, the appendix should be placed after the text and text reference list, and the figures and tables should be numbered separately in the appendix and the text (e.g., Appendix Table, Appendix Figure).

If the appendix has figures or tables and references, the appendix should be placed after the text and text reference list, and both the figures and tables and the references should have new numbering (e.g., Appendix Figure 1, Appendix Table 1, and a separate reference list beginning with reference 1).

Capitalization

Avoid unnecessary capitalization. Follow CMS.

Capitalize any word, including an article, following a colon a) if it begins a full sentence, b) if it begins a subtitle, or c) if it is the first word in a table stub (heading) or cell within a table. This does not apply to subtitles in references (See Uniform Requirements).

accession number

Do not capitalize accession number, and use the abbreviation no. instead of number.

other capitalization preferences

a.m., p.m. (ASM)
California encephalitis virus
Eastern equine encephalomyelitis
Ebola (named after the Ebola River in Zaire)
federal
formalin
Guinea worm disease
Gulf Coast
Internet
Legionnaires' disease
Mercurochrome
Pacific Coast
Simian immunodeficiency virus
Sin Nombre virus
Southeast Asia
Southern blot
St. Louis encephalitis virus
Suramin
Teflon
the Gambia, the Netherlands, The Hague
Gram stain, gram-negative, gram-positive (CBE)
Venezuelan equine encephalomyelitis virus
Web page, Web site, the Web
West Africa (CMS)
Western equine encephalomyelitis virus
Western Hemisphere
Western blot
x-ray

specific designations

Do not capitalize the following words, even when used as specific designations, unless they are part of a title: case, group, series, or patient.

statistical tests

The exact and complete titles of tests are capitalized. When the word test appears with the name of a test that is in written form and that is used as a survey or tool, the word test is capitalized. For tests that involve a process, as is the case with most statistical tests, the word test is not capitalized. (AMA)

For a list of statistical tests and capitalization, see AMA Manual of Style.

titles

Capitalize the first initial of all words except articles, coordinating conjunctions, and prepositions (regardless of length). (ASM)

Exceptions:
Lowercase "to" as a preposition but capitalize as an infinitive.

Ability of Gene xyz To Induce Susceptibility to Penicillin

Lowercase "that" as a subordinating conjunction but capitalize as a relative pronoun.

Evidence That Penicillin-Resistant Strains Are Common
Strains that Are Resistant to Penicillin

Capitalize both words in hyphenated compound adjectives. (ASM)

Penicillin-Resistant Gonorrhea

Titles of books and journals are neither italicized nor placed within quotation marks.

Lowercase specific epithets in the scientific names of organisms in titles as you would in running text: Escherichia coli, NOT Escherichia Coli. (ASM)

trade names

Trade names should generally be capitalized. If a name is not found in dictionary or style manuals, follow author. Do not use ™ and ® with trade names.

words derived from proper nouns

Most words derived from proper nouns are not capitalized

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Geographic Designations

Spell out names of states and U.S. territories and possessions when they stand alone or follow a county name. (AMA)

Use postal abbreviations in references, addresses, or product identification.

XYZ product (ABC Co., Atlanta, GA)

Abbreviate U.S. and U.K. as adjective; write out as noun.

When using in a location or address, use USA and UK.

U.S. citizens
Citizens of the United States

The following cities should be used without the state or country name when listed in references:

Atlanta Cincinnati Madrid Pittsburgh
Amsterdam Cleveland Mexico City Prague
Baltimore Copenhagen Miami Rome
Basel Dallas Milan San Francisco
Beijing Denver Minneapolis Seattle
Belgrade Detroit Montreal St. Louis
Berlin Dublin Moscow Stockholm
Bonn Edinburgh Munich Tokyo
Boston Frankfurt Naples Toronto
Brussels Geneva New Orleans Turin
Budapest Houston New York Uppsala
Buenos Aires Kiev Oslo Vienna
Cairo Leningrad Oxford Warsaw
Cambridge* London Paris Zurich
Chicago Los Angeles Philadelphia  

*Note, Cambridge, Massachusetts should be listed with the state.

In references, omit D.C. from Washington, D.C.

secondary sources

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Numbers

Use SI units or other conventional units of measure (AMA). Some medical measurements, however, follow other conventions.

height (meters) blood pressure (mm Hg)
weight (kilograms) oxygen pressure (cm H20)
volume (liters) blood and clinical chemistry
temperature (Celsius)  

To report both SI and conventional units, repeat the number in parentheses along with the unit of measure.

20 mmol/L (20 meq/L)

Use commas in all numbers with four or more digits.

Exception: 
Dates

2,000 people by 2002

blood factors

factor VIII (Roman)

confidence intervals

Use an en dash in a confidence interval.

(95% CI 0.8–1.6)

equations

Displayed equations and text are not separated with punctuation.

Distance is calculated as follows:

D = x(y)

where D = distance, x = time, and y = rate

But if the same equation is run into text (i.e., not displayed), use a comma.

Distance is calculated as D = x(y), where D = distance and...

In equations, single letter abbreviations and variables are italicized; the surrounding parentheses are not. (ASM)

Word equations have initial capital letters and no end punctuation.

(Number of new cases/Number of people at risk)

figures versus words

Numerals should be used to express numbers in most circumstances (AMA).

Exceptions:

  • Numbers that begin a sentence, title, subtitle, or heading
  • Common fractions
  • Accepted usage such as idiomatic expressions
  • Numbers used as pronouns and other uses of the number one in running text
  • Ordinals first through ninth
  • Numbers spelled out in quotations or published titles

Examples:

  • The relative risk of exposed participants was 3 times that of the controls.
  • In the second phase of the study, 3 of the investigators administered the 5 tests to the 7 remaining participants.
  • Five species were identified.
  • The investigators compared a new laboratory method with the standard one.

Mixed fractions

For less precise measurements, mixed fractions may be used instead of decimals. These expressions usually involve time.

Example:
The patient was hospitalized for 5 1/2 days.

Measures of time

Measures of time are usually expressed as numerals. When dates are provided, numerals should be used for day and year; the month should be spelled out unless listed in a table.

Measures of temperature

Use the degree sign with Celsius measures of temperature.

Example:
The plates were cultured at 20°C.

Beginning of sentence, title, or heading

Use words for any number that begins a sentence, title, subtitle, or heading. Rewording the sentence may be better.

Example:
Five species were identified.

When a unit of measure follows a number that begins a sentence, it too must be written out, even if the same unit is abbreviated elsewhere in the same sentence.

Example:
Two milligrams was administered on day 1, followed by 1 µg on day 2.

Common fractions

Common fractions are expressed with words. Hyphens are used only if the fraction modifies a noun.

Numbers used as pronouns

Spell out numbers when used as pronouns.

Accepted usage

Spell out numbers for generally accepted usage, such as idiomatic expressions. "One" frequently appears in running text without referring to a quantity and may appear awkward to the reader if expressed as a numeral. When "one" may be replaced by "a" or "a single" without changing the meaning, the word one, rather than the numeral, is appropriate.

Ordinals

Ordinals generally express order or rank rather than quantity. Ordinals first through ninth are spelled out. Ordinals greater than ninth are expressed as numerals, except at the beginning of sentence, title, or heading.

Exceptions:
Ordinals that are part of a series that includes an ordinal greater than ninth

Combining numerals and words

Use a combination of numerals and words to express rounded large numbers and consecutive numerical expressions.

Examples:
The disease affects 5 million to 6 million persons.
Study participants were given twenty 5-mL syringes.

numbered lists

Avoid unless necessary; use Arabic numbers followed by single parentheses (to avoid confusion with references). (CBE)

Three conditions were met: 1) handwashing procedures, once not strictly followed, were enforced; 2) isolation procedures were instituted; and 3) staff were trained in additional preventive measures.

percentages 

Immediately follow the number, not the phrase.

The disease was found in 12 (50%) of the 24 children at the picnic.

ranges

Limit to specific statistical meaning. In text, when followed by a preposition, use "to."

from 18 to 20 years
from 5% to 10%
from 1984 to 1990

Use the en dash to connect percentages.

25%–35%

Repeat symbols in ranges, but do not repeat words. (AMA)

40ºC to 70ºC, 25% to 50%
The angles varied by five to six degrees.

ratios

Use colon (length:width, 2:1).

virus designations

HIV-1, HIV-2 (Arabic)
HTLV-III (Roman)

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Comments to the EID Editors
Please contact the EID Editors at eideditor@cdc.gov

 

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This page last reviewed October 25, 2004

Emerging Infectious Diseases Journal
National Center for Infectious Diseases
Centers for Disease Control and Prevention