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Genomics and Health Weekly Update

Human Genome Epidemiology (HuGE) Articles
August 2, 2007
Volume 19, No. 5

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Many of the news links published in our Weekly Update are temporary, and we cannot guarantee access to stories longer than one or two weeks after the Update is published. We suggest you contact the news source directly for reprints.

These articles report on population prevalence of genotypes, gene-disease associations, gene-environment and gene-gene interactions and evaluation of genetic tests.



Gene Variant Frequency

Systematic sequence analysis of the human fucosyltransferase 2 (FUT2) gene identifies novel sequence variations and alleles
Yip SP, et al.
Transfusion 2007 Aug;47(8):1369-80

Haplotype Diversity in Four Genes (CLCNKA, CLCNKB, BSND, NEDD4L) Involved in Renal Salt Reabsorption
Sile S, et al.
Hum Hered 2007 Jul;65(1):33-46

 

Infectious and Parasitic Diseases

Impact of serum levels and gene polymorphism of cytokines on chronic hepatitis C infection
Chen TY, et al.
Transl Res 2007 Aug;150(2):116-21

 

Neoplasms

Vitamin D receptor gene polymorphisms and risk of non-Hodgkin's lymphoma
Purdue MP, et al.
Haematologica 2007 Aug;92(8):1145-6

FcgammaRIIIA and FcgammaRIIA polymorphisms do not predict clinical outcome of follicular non-Hodgkin's lymphoma patients treated with sequential CHOP and rituximab
Carlotti E, et al.
Haematologica 2007 Aug;92(8):1127-30

Polymorphisms of the DNA repair gene xeroderma pigmentosum groups A and C and risk of esophageal squamous cell carcinoma in a population of high incidence region of North China
Guo W, et al.
J Cancer Res Clin Oncol 2007 Jul

Sun exposure, vitamin D receptor gene polymorphisms and risk of non-Hodgkin lymphoma
Purdue MP, et al.
Cancer Causes Control 2007 Jul

GSTM1 and codon 72 P53 polymorphism in multiple myeloma
Ortega MM, et al.
Ann Hematol 2007 Jul

The role of genetic factor in etiopathogenesis of squamous cell carcinoma of the head and neck in young adults
Gawecki W, et al.
Eur Arch Otorhinolaryngol 2007 Jul

The involvement of IL-10, IL-6, IFN-gamma, TNF-alpha and TGF-beta gene polymorphisms among Turkish lung cancer patients
Colakogullari M, et al.
Cell Biochem Funct 2007 Jul

Polymorphisms of methylenetetrahydrofolate reductase (MTHFR), methionine synthase (MTR), methionine synthase reductase (MTRR), and thymidylate synthase (TYMS) in multiple myeloma risk
Lima CS, et al.
Leuk Res 2007 Jul

Significance of an E-cadherin gene promoter polymorphism for risk and disease severity of prostate cancer in a Japanese population
Goto T, et al.
Urology 2007 Jul;70(1):127-30

 

Endocrine, Nutritional and Metabolic Diseases

Lipoprotein lipase PvuII polymorphism is associated with variations in serum lipid levels in non-diabetic pregnant women
Sepetiba RJ, et al.
Braz J Med Biol Res 2007 Jul;40(7):919-26

Effects of a PPARG gene variant on obesity characteristics in Brazil
Mattevi VS, et al.
Braz J Med Biol Res 2007 Jul;40(7):927-32

 

Diseases of the Blood & Blood-Forming Organ Disorders

Interferon-gamma +874A/T and interleukin-4 intron3 VNTR gene polymorphisms in Chinese patients with idiopathic thrombocytopenic purpura
Chen X, et al.
Eur J Haematol 2007 Jul

 

Mental Disorders

Pharmacogenetic clinical trial of sustained-release bupropion for smoking cessation
David SP, et al.
Nicotine Tob Res 2007 Aug;9(8):821-33

Relationship between dopamine system genes and extraversion and novelty seeking
Golimbet VE, et al.
Neurosci Behav Physiol 2007 Jul;37(6):601-6

Association analysis of G72/G30 polymorphisms with schizophrenia in the Korean population
Shin HD, et al.
Schizophr Res 2007 Jul

Association of dopamine receptor polymorphisms with schizophrenia and antipsychotic response in a South Indian population
Vijayan NN, et al.
Behav Brain Funct 2007 Jul;3(1):34

Association Study of MAO-A and DRD4 Genes in Schizophrenic Patients with Aggressive Behavior
Fresan A, et al.
Neuropsychobiology 2007 Jul;55(3-4):171-5

 

Diseases of the Nervous System and Sense Organs

Lack of Association between the BDNF Gene Val66Met Polymorphism and Alzheimer Disease in a Chinese Han Population
He XM, et al.
Neuropsychobiology 2007 Jul;55(3-4):151-5

Matrix metalloproteinase-9 -1562 C/T gene polymorphism in Serbian patients with multiple sclerosis
Zivkovic M, et al.
J Neuroimmunol 2007 Jul

Preservation of Gray Matter Volume in Multiple Sclerosis Patients with the Met Allele of the rs6265 (Val66Met) SNP of Brain Derived Neurotrophic Factor (BDNF)
Zivadinov R, et al.
Hum Mol Genet 2007 Jul

Variability in the kinesin light chain 1 gene may influence risk of age-related cataract
Andersson ME, et al.
Mol Vis 2007;13:993-6

Candidate gene and locus analysis of myopia
Mutti DO, et al.
Mol Vis 2007;13:1012-9

Mutation screening and haplotype analysis of the rhodopsin gene locus in Japanese patients with retinitis pigmentosa
Ando Y, et al.
Mol Vis 2007;13:1038-44

HLA-A Confers an HLA-DRB1 Independent Influence on the Risk of Multiple Sclerosis
Brynedal B, et al.
PLoS ONE 2007;2:e664

High prevalence of mutations in peripherin/RDS in autosomal dominant macular dystrophies in a Spanish population
Gamundi MJ, et al.
Mol Vis 2007;13:1031-7

 

Diseases of the Circulatory System

Cytotoxic T Lymphocyte Antigen 4 Gene Polymorphism Associated With ST-Segment Elevation Acute Myocardial Infarction
Yip HK, et al.
Circ J 2007 Aug;71(8):1213-8

Impact of delta-sarcoglycan gene polymorphism on the occurrence of coronary spastic angina in Japanese patients with hypertrophic cardiomyopathy
Honda T, et al.
Circ J 2007 Aug;71(8):1263-7

The risk of recurrent venous thromboembolism among heterozygous carriers of factor V Leiden or prothrombin G20210A mutation. A systematic review of prospective studies
Marchiori A, et al.
Haematologica 2007 Aug;92(8):1107-14

Synergistic contribution of CD14 and HLA loci in the susceptibility to Buerger disease
Chen Z, et al.
Hum Genet 2007 Jul

Association of Plasminogen Activator Inhibitor (PAI)-1 (SERPINE1) SNPs with Myocardial Infarction, Plasma PAI-1, and Metabolic Parameters. The HIFMECH Study
Morange PE, et al.
Arterioscler Thromb Vasc Biol 2007 Jul

Resequencing PNMT in European hypertensive and normotensive individuals: no common susceptibilily variants for hypertension and purifying selection on intron 1
Kepp K, et al.
BMC Med Genet 2007 Jul;8(1):47

PDE4D and ALOX5AP genetic variants and risk for Ischemic Cerebrovascular Disease in Sweden
Kostulas K, et al.
J Neurol Sci 2007 Jul

 

Diseases of the Respiratory System

Transforming growth factor-beta(2) polymorphisms are associated with childhood atopic asthma
Hatsushika K, et al.
Clin Exp Allergy 2007 Aug;37(8):1165-74

Relationship between glutathione S-transferase gene polymorphisms and enzyme activity in Hong Kong Chinese asthmatics
Mak JC, et al.
Clin Exp Allergy 2007 Aug;37(8):1150-7

Polymorphisms of histamine-metabolizing enzymes and clinical manifestations of asthma and allergic rhinitis
Garcia-Martin E, et al.
Clin Exp Allergy 2007 Aug;37(8):1175-82

MBL2 variants in relation to common childhood infections and atopy-related phenotypes in a large German birth cohort
Muller S, et al.
Pediatr Allergy Immunol 2007 Jul

Effects of antioxidant enzyme polymorphisms on ozone-induced lung function changes
Chen C, et al.
Eur Respir J 2007 Jul

 

Diseases of the Digestive System

Sex-related influence of angiotensin-converting enzyme polymorphisms on fibrosis progression due to recurrent hepatitis C after liver transplantation
Fabris C, et al.
J Gastroenterol 2007 Jul;42(7):543-9

 

Diseases of the Genitourinary System

Interleukin-6 gene polymorphism and faster progression to end-stage renal failure in chronic glomerulonephritis
Buraczynska M, et al.
Transl Res 2007 Aug;150(2):101-5

Polymorphisms in CYP1A1 gene are associated with male infertility in a Chinese population
Lu N, et al.
Int J Androl 2007 Jul

Androgen receptor gene haplotype is associated with male infertility
Saare M, et al.
Int J Androl 2007 Jul

 

Complications of Pregnancy, Childbirth, and the Puerperium

The genetic predisposition to produce high levels of TGF-beta1 impacts on the severity of eclampsia/pre-eclampsia
Stanczuk GA, et al.
Acta Obstet Gynecol Scand 2007;86(8):903-8

 

Diseases of the Skin and Subcutaneous Tissue

Association of Angiotensin-converting enzyme gene insertion/deletion polymorphism with allergic contact dermatitis
Nacak M, et al.
Basic Clin Pharmacol Toxicol 2007 Aug;101(2):101-3

 

Diseases of the Musculoskeletal System and Connective Tissue

A Differential Association of ALOX15 Polymorphisms with Bone Mineral Density in Pre- and Post-Menopausal Women
Cheung CL, et al.
Hum Hered 2007 Jul;65(1):1-8

Association analysis of functional variants of the FcgRIIa and FcgRIIIa genes with type 1 diabetes, celiac disease and rheumatoid arthritis
Alizadeh BZ, et al.
Hum Mol Genet 2007 Jul

 

Certain Conditions Originating in the Perinatal Period

Mannose-binding lectin polymorphisms and pulmonary outcome in premature neonates: a pilot study
Capoluongo E, et al.
Intensive Care Med 2007 Jul

 

Symptoms, Signs and Ill-defined Conditions

Do motor control genes contribute to interindividual variability in decreased movement in patients with pain?
Mishra BK, et al.
Mol Pain 2007 Jul;3(1):20

 

 

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Page last reviewed: August 2, 2007 (archived document)
Page last updated: November 2, 2007
Content Source: National Office of Public Health Genomics