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 Thursday, January 3, 2008 Volume 20   Number 1
Update banner Family History Population Research Genomics in Practice General Public
This weekly update provides information about the impact of human genetic research on disease prevention & public health. open mailbox for email deliveryGet email updates
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blue dotAnnouncements
blue dotGenomics In The News
blue dotScientific Literature
blue dotHuGE Articles
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 Upcoming Events

ISCTR 1st Annual Symposium: Sharing the Future in the Latest Adv. of Cellular Therapy & Genomics in Cardiovascular Disease non-gov warning icon

Integrative Cancer
Genomics  non-gov warning icon

American College of Medical Genetics (ACMG) 15th Annual Clinical Genetics Meeting  non-gov warning icon


 Let's Go Surfing

Best Careers-Genetic Counselor: Executive Summary  non-gov warning icon

Understanding Gene
Testing non-gov warning icon

DNA Interactive non-gov warning icon

CDC Celebrates 10 Years of Public Health Genomics - January 23, 2008
helix CDC Celebrates 10 Years of Public Health Genomics
On January 23, 2008, CDC’s National Office of Public Health Genomics will host a landmark event, highlighting progress and achievements in the
field of public health genomics during the last 10 years.
dot Learn more
Genomics Announcements
 
bullhorn
 The independent EGAPP Working Group non-gov warning icon released the first in a planned series of recommendation statements on the use of genetic tests in clinical practice. This first statement addresses the use of cytochrome P450 (CYP450) testing in adults with depression treated with a widely prescribed class of antidepressants.
> Read more about the EGAPP initiative
> Read CDC Press Statement
   
CDC sponsored material
 CDC's National Office of Public Health Genomics announces a new funding opportunity for those interested in genomics translation research.


Genomics In The News

  • The following are headlines from on-line news articles published during the past week.
  • The headlines and lead sentence are exactly as they appear in the popular press & do not necessarily reflect the opinions or recommendations of CDC.
  • Free registration required for some articles.

Cancer

Colon cancer gene traced to possible pilgrim ancestor, non-gov warning icon Medical News Today, January 2

'Swish And Spit' test accurate for cancer, non-gov warning icon Medical News Today, January 2

Lung cancer cells' survival gene seen as drug target, non-gov warning icon Medical News Today, January 2

Study examines genetic defects linked to body abnormalities in patients with childhood cancer, non-gov warning icon EurekAlert, January 1

Study links ovarian cancer survival to gene change, non-gov warning icon Yahoo News, January 2

Breast cancer gene mutation more common in Hispanic, young black women, non-gov warning icon News-Medical.Net, December 30

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Other News

In treating muscular dystrophy, an early drug test shows promise, non-gov warning icon International Herald Tribune, January 2

 In the absence of a gene that says 'yes' or 'no,' the value of one that says 'maybe' is questioned, non-gov warning icon International Herald Tribune, December 26

Solutions sought to reproductive problems related to chromosomal variations, non-gov warning icon Medical News Today, January 2

DNA sequencing more cost effective using new technique, non-gov warning icon Medical News Today, December 25

Gene variation may elevate risk of liver tumor in patients with cirrhosis, non-gov warning icon EurekAlert, January 1

New gene prediction method capitalizes on multiple genomes, non-gov warning icon Medical News Today, December 22

Copy number variation may stem from replication misstep, non-gov warning icon News-Medical.Net, December 30

A genetic influence on alcohol addiction found - lack of endorphin, non-gov warning icon News-Medical.Net, December 21

Personalized medicine will alter treatment of genetic disorders, non-gov warning icon News-Medical.Net, December 30

Genetic counselor shows patients the options, Baltimore Sun, non-gov warning icon December 21

Two genes are important key to regulating immune response - Findings have implications for research into lupus, cancer and HIV/AIDS, non-gov warning icon Medical News Today, December 29

Science's 'Breakthrough of the year' - Human genetic variation, Medical News Today, non-gov warning icon December 21

Perfect Strangers, genetic kin, non-gov warning icon New York Times, December 28

Studies on genetics and stem cell research, stents included in top10 research advances, American Heart Association, non-gov warning icon Medical News Today, December 21

Searching for similar diagnosis through DNA, International Herald Tribune, non-gov warning icon December 28

Tweaking a gene may fix Fragile X syndrome, non-gov warning icon News-Medical.Net, December 20

Cognitive, genetic clues identified in imaging study of alcohol addiction, non-gov warning icon Medical News Today, December 27

  
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Genomics in Scientific Literature
Featured Item

Meta- and Pooled Analyses of the Methylenetetrahydrofolate Reductase C677T and A1298C Polymorphisms and Gastric Cancer Risk: A Huge-GSEC Review
Boccia S, et al.
Am J Epidemiol 2007 Dec
 General Articles

What will whole genome searches for susceptibility genes for common complex disease offer to clinical practice?
Lango H & Weedon MN
J Intern Med 2008 Jan;263(1):16-27

Gender, a significant factor in the cross talk between genes, environment, and health
Ordovas JM
Gend Med 2007;4S2:S111-S122

A lesson not learned: allele misassignment
Sand PG
Behav Brain Funct 2007 Dec;3(1):65

Genetic polymorphisms of human cytosol glutathione S-transferases and prostate cancer
Katoh T, et al.
Pharmacogenomics 2008 Jan;9(1):93-104

Pharmacogenetics of aspirin-intolerant asthma
Kim SH, et al.
Pharmacogenomics 2008 Jan;9(1):85-91

Long-term treatment of familial male-limited precocious puberty (testotoxicosis)  with cyproterone acetate or ketoconazole
Almeida MQ, et al.
Clin Endocrinol (Oxf) 2007 Dec

The serotonin transporter gene and effectiveness of SSRIs
Alessandro S & Kato M
Expert Rev Neurother 2008 Jan;8(1):111-20

Advances in the genetics of Parkinson's disease
Rosner S, et al.
Acta Pharmacol Sin 2008 Jan;29(1):21-34

Improved correction for population stratification in genome-wide association studies by identifying hidden population structures
Li Q & Yu K
Genet Epidemiol 2007 Dec

The emerging landscape of breast cancer susceptibility
Stratton MR & Rahman N
Nat Genet 2008 Jan;40(1):17-22

Very low birth weight infants as a model to study genetic influences on neonatal  weight gain
Spiegler J, et al.
J Pediatr Gastroenterol Nutr 2008 Jan;46(1):113-6

Controlling false discoveries in genetic studies
van den Oord EJ
Am J Med Genet B Neuropsychiatr Genet 2007 Dec

Estimating Interaction Between Genetic and Environmental Risk Factors: Efficiency of Sampling Designs Within a Cohort
Bureau A, et al.
Epidemiology 2008 Jan;19(1):83-93

 

 Genetic Testing

Genetics of Parkinson disease
Pankratz N & Foroud T
Genet Med 2007 Dec;9(12):801-11

Review of evidence for genetic testing for CYP450 polymorphisms in management of  patients with nonpsychotic depression with selective serotonin reuptake inhibitors
Thakur M, et al.
Genet Med 2007 Dec;9(12):826-35

 

 Family History

Are Depressed Outpatients With and Without a Family History of Substance Use Disorder Different? A Baseline Analysis of the STAR*D Cohort
Davis LL, et al.
J Clin Psychiatry 2007 Dec;68(12):1931-8

ApoE Distribution and Family History in Genetic Prion Diseases in Germany
Krasnianski A, et al.
J Mol Neurosci 2008 Jan;34(1):45-50

Risk Factors for Prostate Cancer in Men Aged Less Than 60 Years: A Case-Control Study from Italy
Gallus S, et al.
Urology 2007 Dec;70(6):1121-6
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HuGE Published Literature [ back to top ]

Articles that report on population prevalence of genotypes, gene-disease associations, gene-environment and gene-gene interactions and evaluation of genetic tests. For more information on HuGE, please visit the HuGENet™ home page

For the week ending January 2, 2008, there are HuGE articles in the following areas:

Gene Variant Frequency
Infectious and Parasitic Diseases
Neoplasms
Endocrine, Nutritional and Metabolic Diseases
Diseases of the Blood and Blood-Forming Organs Disorders
Mental Disorders
Diseases of the Nervous System and Sense Organs
Diseases of the Circulatory System
Diseases of the Respiratory System
Diseases of the Digestive System
Diseases of the Genitourinary System
Complications of Pregnancy, Childbirth, and the Puerperium
Diseases of the Skin and Subcutaneous Tissue
Diseases of the Musculoskeletal System and Connective Tissue
Congenital Anomalies
Certain Conditions Originating in the Perinatal Period

For more information on HuGE, please visit the HuGENet™ home page

 

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Page last updated: January 3, 2008 (archived document)
Content Source: National Office of Public Health Genomics