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Thursday, December 20, 2007 |
Volume
19 Number 24 |
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![Happy Holidays](https://webarchive.library.unt.edu/eot2008/20090121030017im_/http://www.cdc.gov/genomics/update/file/images/banner_holidays.gif)
CDC's National Office of Public Health Genomics will not be publishing or sending the Genomics and
Health Weekly Update next week. The NOPHG staff wish you a wonderful holiday season! |
This weekly update provides information about the impact of human genetic research on disease prevention & public health. |
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Cancer |
Researchers initiate gene therapy trial in patients with advanced skin cancer, News-Medical.Net, December 19 |
The International Myeloma Foundation identifies potential link between genetic pathways and environmental risks for myeloma, Medical News Today, December 13 |
Bowel cancer genes that triple risk discovered, News-Medical.Net, December 17 |
Most carriers of Fanconi anemia genes are not at a higher risk of cancer, News-Medical.Net, December 13 |
Herceptin helps women with multiple chromosomes containing HER2 gene, Medical News Today, December 15 |
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Family History |
A family health portrait, Syracuse.com, December 18 |
Family gene puts men at risk for breast cancer, ABC News, December 14 |
Your family medical history may save your child's life, Imperial Valley News, December 16 |
Spotting family health risks could result in a life saving gift, Blackanthem.com, December 14 |
Men unaware of their risk of cancer when female family members test positive for cancer causing gene mutation, Medical News Today, December 15 |
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Genetic Testing |
Evidence Doesn't Support CYP450 Gene Testing before Antidepressant Treatment, Newswise, December 19 |
As gene tests spread, questions follow, Wall Street Journal, December 13 |
Emory, Ohio State launch partnership in predictive and personalized health care, EurekAlert, December 18 |
Carbamazepine prescribing information to include recommendation of genetic test for patients with Asian ancestry, Medical News Today, December 14 |
Gene test can indicate whether Tamoxifen can fight breast cancer, ABC News, December 17 |
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Other News |
NIH launches Human Microbiome Project, NIH News, December 19 |
Study uncovers clues to cystic fibrosis gene dysfunction and gastrointestinal disease, News-Medical.Net, December 17 |
Association discovered between genes regulating glucose metabolism and Spina Bifida, Medical News Today, December 19 |
International research collaboration narrows focus on genetic cause of Kawasaki disease, EurekAlert, December 16 |
Discovery of new ALS gene, News-Medical.Net, December 19 |
Groundbreaking genome project to be piloted by BGSU undergraduates, Medical News Today, December 15 |
Twin study indicates genetic basis for processing faces, places, Medical News Today, December 19 |
Panning the region for genetic gold, The Chronicle Herald, December 15 |
Boy living in bubble develops leukemia from experimental therapy, Fox News, December 18 |
Trendspotter: Gene scene, FT.com, December 15 |
New hope for sleep disorders: Genetic switch for circadian rhythms discovered, Science Daily, December 18 |
Agency approves drug to treat genetic disorder that can lead to retardation, The New York Times, December 14 |
Quebec announces register to add genetic typing to blood transfusions,
(last accessed 2/2008) CBC News, December 18 |
Genetics may boost Mexican-Americans' risk for alcoholism, Washington Post, December 13 |
Mutation in one gene tied to Lou Gehrig's
disease, Reuters Health, December 17 |
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Clustered Environments and Randomized Genes: A Fundamental Distinction between Conventional and Genetic Epidemiology
Smith GD, et al.
PLoS Med 2007 Dec;4(12):e352
Retention of African American women in cancer genetics research
Halbert CH, et al.
Am J Med Genet A 2007 Dec
Genetic susceptibility in pancreatic ductal adenocarcinoma
Lochan R, et al.
Br J Surg 2007 Dec
PTPN22: its role in SLE and autoimmunity
Chung SA & Criswell LA
Autoimmunity 2007 Dec;40(8):582-90
Fc receptor genes and the systemic lupus erythematosus diathesis
Brown EE, et al.
Autoimmunity 2007 Dec;40(8):567-81
Utah Family-Based Analysis: Past, Present and Future
Cannon Albright LA
Hum Hered 2007 Dec;65(4):209-20
Universal False Discovery Rate Estimation Methodology for Genome-Wide Association Studies
Forner K, et al.
Hum Hered 2007 Dec;65(4):183-94
Hereditary Breast Cancer: Part I. Diagnosing Hereditary Breast Cancer Syndromes
Lynch HT, et al.
Breast J 2007 Dec
Hereditary Breast Cancer: Part II. Management of Hereditary Breast Cancer: Implications of Molecular Genetics and Pathology
Silva E, et al.
Breast J 2007 Dec
Genetics of late-onset Alzheimer's disease: progress and prospect
Li Y & Grupe A
Pharmacogenomics 2007 Dec;8(12):1747-55
Endothelial nitric oxide synthase gene: prospects for treatment of heart disease
Cooke GE, et al.
Pharmacogenomics 2007 Dec;8(12):1723-34
Three lectures on case control genetic association analysis
Li W
Brief Bioinform 2007 Dec
Novel primary immunodeficiencies revealed by the investigation of paediatric infectious diseases
Bustamante J, et al.
Curr Opin Immunol 2007 Dec
Genetic developments in autoimmune thyroid disease: an evolutionary process
Zeitlin AA, et al.
Clin Endocrinol (Oxf) 2007 Dec
Translational mini-review series on complement factor H: genetics and disease associations of human complement factor H
de Cordoba SR & de Jorge EG
Clin Exp Immunol 2008 Jan;151(1):1-13
NPC-db, a Niemann-Pick type C disease gene variation database
Runz H, et al.
Hum Mutat 2007 Dec
Information Disclosure in Population-Based Research Involving Genetics: A Framework for the Practice of Ethics in Epidemiology
Kristman VL & Kreiger N
Ann Epidemiol 2007 Dec
Research highlights from the literature
Jordan J
Clin Auton Res 2007 Dec;17(6):331-3
Assessment of the psychological effects of genetic screening for hereditary hemochromatosis
Elsass P, et al.
Ann Hematol 2007 Dec
Adipose tissue-specific PPARgamma deficiency increases resistance to oxidative stress
Luo W, et al.
Exp Gerontol 2007 Nov
Health-related quality of life in a racially diverse population screened for hemochromatosis: results from the Hemochromatosis and Iron Overload Screening (HEIRS) study
Wenzel LB, et al.
Genet Med 2007 Oct;9(10):705-12
Genetic screening for reproductive purposes at school: Is it a good strategy?
Frumkin A & Zlotogora J
Am J Med Genet A 2007 Dec
Molecular Diagnostics in Autosomal Dominant Polycystic Kidney Disease: Utility and Limitations
Zhao X, et al.
Clin J Am Soc Nephrol 2007 Dec
Screening for dyslipidemia based on family history combined with obesity in children
Yan H, et al.
Beijing Da Xue Xue Bao 2007 Dec;39(6):591-4
Genetics: What Advice for Patients Who Present With a Family History of Melanoma?
Newton Bishop JA & Gruis NA
Semin Oncol 2007 Dec;34(6):452-9
Universal risk factors for multifactorial diseases : LifeLines: a three-generation population-based study
Stolk RP, et al.
Eur J Epidemiol 2007 Dec
Family history and the risk of oral and pharyngeal cancer
Garavello W, et al.
Int J Cancer 2007 Dec
Morbidity and mortality in first-degree relatives of C282Y homozygous probands with clinically detected haemochromatosis compared with the general population: the Hemochromatosis FAmily Study (HEFAS)
Jacobs EM, et al.
Neth J Med 2007 Dec;65(11):425-33
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Articles that report on population prevalence of genotypes, gene-disease associations, gene-environment and gene-gene interactions and evaluation of genetic tests. For more information on HuGE, please visit the HuGENet™ home page
For the week ending December 19, 2007, there are HuGE articles in the following areas:
Gene Variant Frequency
Infectious and Parasitic Diseases
Neoplasms
Endocrine, Nutritional and Metabolic Diseases
Diseases of the Blood and Blood-Forming Organs Disorders
Mental Disorders
Diseases of the Nervous System and Sense Organs
Diseases of the Circulatory System
Diseases of the Respiratory System
Diseases of the Digestive System
Diseases of the Genitourinary System
Complications of Pregnancy, Childbirth, and the Puerperium
Diseases of the Skin and Subcutaneous Tissue
Diseases of the Musculoskeletal System and Connective Tissue
Symptoms, Signs, and Ill-defined Conditions
For more information on HuGE, please visit the HuGENet™ home page
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Provides link to non-governmental sites and does not necessarily represent the views of the Centers for Disease Control and Prevention. |
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Page last updated: December 20, 2007 (archived document)
Content Source: National Office of Public Health Genomics |
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