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 Thursday, July 24, 2008 Volume 21   Number 4
Family History Population Research Genomics in Practice General Public
This weekly update provides information about the impact of human genomic research on disease prevention & population health. open mailbox for email deliveryGet email updates
Spotlight

newborn sleeping
CDC Celebrates 30 Years of the Newborn Screening Quality Assurance Program
July marks 30 years of CDC’s Newborn Screening Quality Assurance Program, the only comprehensive program in the world devoted to quality assurance of newborn screening tests. Because of this program, thousands of babies are saved from death and disability each year.
Read more.

Sections

 >  View Current Update
blue dotAnnouncements
blue dotGenomics In The News
blue dotScientific Literature
blue dotHuGE Articles
blue dotBack Issues

 Upcoming Events

California Officials Advance Efforts To Rein In Direct-to-Consumer Genetic Testing Firms non-gov warning icon

Construct Forums on Genetics: A How-To
Guide
non-gov warning icon

GenePoPS non-gov warning icon

Genomics Announcements
 

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Victor Almon McKusick, M.D., University Professor at the Johns Hopkins University School of Medicine, known as the “Father of Medical Genetics,” died Tuesday, July 22, 2008. Read the press release. non-gov warning icon
   
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The National Institutes of Health announces two new funding opportunities for genomics translation research.
   
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Michigan Department of Community Health to assess consumer awareness and use of personal genome profiles. Read the 2009 Genomics BRFS survey proposal,Word document(30KB) which can serve as a model for other interested states. Have questions? Send CDC an email at genetics@cdc.gov. Learn more about the BRFSS.

   
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Save the date! University of Washington to hold Summer Institute on Public Health Genomics June 15 - July 1, 2009. For more information, please contact Leslie Pfeifer.

   
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What's New at HuGENet™
July 2008


Genomics In The News

  • The following are headlines from on-line news articles published during the past week.
  • The headlines and lead sentence are exactly as they appear in the popular press & do not necessarily reflect the opinions or recommendations of CDC.
  • Free registration required for some articles.

Cancer

Familial and genetic risk of transitional cell carcinoma of the urinary tract, non-gov warning icon Medical News Today, July 24

Gene profiles might help guide lung cancer care, non-gov warning icon Medline Plus, July 21

GeneNews launches world's first blood test for colorectal cancer screening, non-gov warning icon Medical News Today, July 22

New approach to cancer: Find most tightly controlled genes, non-gov warning icon e! Science News, July 21

New gene combination may cause deadly prostate cancer, non-gov warning icon Medical News Today, July 22

Researchers target specific genes, reduce cancer cells, non-gov warning icon Medical News Today, July 18

No need for gene screens in breast cancer families, non-gov warning icon News-Medical.Net, July 22

 

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ELSI (Ethical, Legal and Social Issues)

Should genetic tests be regulated, non-gov warning icon Yahoo News, July 23

'Ten Commandments' of race and genetics
issued
, non-gov warning icon New Scientist, July 17

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Genetic Testing

What you should know before you spit into that test tube, non-gov warning icon Washington Post, July 20

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Mental Health

Gene interacts with hormone to impair thinking, non-gov warning icon Reuters Health, July 22

Using genetics to improve traditional psychiatric diagnoses, non-gov warning icon Science Daily, July 17

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Pharmacogenetics

New study replicates association between genetic variation and antidepressant treatment response, non-gov warning icon Science Daily, July 17

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Other News

Lazy eye discovery: How an old gene learns new tricks, non-gov warning icon Medical News Today, July 24

Hutterites are model gene community, non-gov warning icon Scientific American, July 21

Victor McKusick, 86, dies; Medical genetics pioneer, non-gov warning icon The New York Times, July 24

Latest findings presented by researcher helping to pioneer medical therapy for Fragile X, non-gov warning icon Medical News Today, July 21

Gene tied to muscle weakness from cholesterol drugs, non-gov warning icon Reuters Health, July 23

Scientists define 21 new genes associated with Crohn’s disease, non-gov warning icon NIH News, July 21

Australian study seeks genetic roots of cerebral palsy, non-gov warning icon Yahoo News, July 21

Increased triglyceride levels in Asian-Americans with genetic variant, non-gov warning icon Medical News Today, July 18

Genetic mechanisms at play in blood cells important in Parkinson’s disease, non-gov warning icon News-Medical.Net, July 21

Fred Hutchinson awarded $7.6 million to research how genetic variations influence risk of common diseases, non-gov warning icon News-Medical.Net, July 17

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Genomics in Scientific Literature
Featured Item

Genetic Research in Schizophrenia: New Tools and Future Perspectives
Bertram L
Schizophr Bull 2008 Jul


 General Articles

Combined haplotype relative risk (CHRR): a general and simple genetic association test that combines trios and unrelated case-controls
Guo CY, et al.
Genet Epidemiol 2008 Jul

Cancer genomics and genetics of FGFR2 (Review)
Katoh M
Int J Oncol 2008 Aug;33(2):233-7

Molecular genetics of atrial fibrillation
Tsai CT, et al.
J Am Coll Cardiol 2008 Jul;52(4):241-50

Disease associations and family-based tests
Ewens WJ, et al.
Curr Protoc Hum Genet 2008 Jul;Chapter 1:Unit 1.12

Role of UGT1A1 *28 and UGT1A1 *6 for Irinotecan-induced Adverse Drug Reaction
Onoue M & Inui K
Gan To Kagaku Ryoho 2008 Jul;35(7):1080-5

Guidelines for Diagnosis of Cystic Fibrosis in Newborns through Older Adults: Cystic Fibrosis Foundation Consensus Report
Farrell PM, et al.
J Pediatr 2008 Aug;153(2):S4-S14

The genetics of clinical outcome in multiple sclerosis
Ramagopalan SV, et al.
J Neuroimmunol 2008 Jul

Schizophrenia: from genes to phenes to disease
Allan CL, et al.
Curr Psychiatry Rep 2008 Aug;10(4):339-43

The clinical impact of pharmacogenetics on the treatment of epilepsy
Loscher W, et al.
Epilepsia 2008 Jul

The continued need to synthesize the results of genetic associations across multiple studies
Yesupriya A, et al.
Genet Med 2008 Jul

Acquisition and disclosure of genetic information under alternative policy regimes: an economic analysis
Wilson D
Health Econ Policy Law 2006 Jul;1(Pt 3):263-76

Function2Gene: a gene selection tool to increase the power of genetic association studies by utilizing public databases and expert knowledge
Armstrong DL, et al.
BMC Bioinformatics 2008 Jul;9(1):311

The Application of Genetic Information for Regulatory Standard Setting Under the  Clean Air Act: A Decision-Analytic Approach
Cullen AC, et al.
Risk Anal 2008 Jul

Genes and irritable bowel syndrome: is there a link?
Saito YA
Curr Gastroenterol Rep 2008 Aug;10(4):355-62

Parallel and serial computing tools for testing single-locus and epistatic SNP effects of quantitative traits in genome-wide association studies
Ma L, et al.
BMC Bioinformatics 2008 Jul;9(1):315

A comprehensive review of the genetics of juvenile idiopathic arthritis
Prahalad S & Glass DN
Pediatr Rheumatol Online J 2008 Jul;6(1):11

Bayes factors for genome-wide association studies: comparison with P-values
Wakefield J
Genet Epidemiol 2008 Jul


 Family History

Family history of chronic disease and participation in healthy behaviours
Gibbison GA & Johnson CD
Health Econ Policy Law 2007 Jul;2(Pt 3):297-315

The impact of family history of breast cancer and cancer death on women's mammography practices and beliefs
Tracy KA, et al.
Genet Med 2008 Jul

Effect of parental family history of Alzheimer's disease on serial position profiles
La Rue A, et al.
Alzheimers Dement 2008 Jul;4(4):285-90

 

 Genetic Testing

The phases of disclosing BRCA1/2 genetic information to offspring
Clarke S, et al.
Psychooncology 2008 Jul

Genetic susceptibility of diabetic retinopathy
Patel S, et al.
Curr Diab Rep 2008 Aug;8(4):257-62

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HuGE Published Literature [ back to top ]

Articles that report on population prevalence of genotypes, gene-disease associations, gene-environment and gene-gene interactions and evaluation of genetic tests. For more information on HuGE, please visit the HuGENet™ home page

For the week ending July 23, 2008, there are HuGE articles in the following areas:

Gene Variant Frequency
Infectious and Parasitic Diseases
Neoplasms
Endocrine, Nutritional and Metabolic Diseases
Mental Disorders
Diseases of the Nervous System and Sense Organs
Diseases of the Circulatory System
Diseases of the Respiratory System
Diseases of the Digestive System
Diseases of the Genitourinary System
Complications of Pregnancy, Childbirth, and the Puerperium
Diseases of the Skin and Subcutaneous Tissue
Diseases of the Musculoskeletal System and Connective Tissue
Congenital Anomalies
Certain Conditions Originating in the Perinatal Period
Injury and Poisoning

For more information on HuGE, please visit the HuGENet™ home page

 

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Page last updated: July 24, 2008 (archived document)
Content Source: National Office of Public Health Genomics