Genetic Information Nondiscrimination Act (GINA)  passes in the U.S. Senate Thursday, April 24th. GINA will protect against the misuse of Americans' genetic information. The Act will return to the U.S. House of Representatives before being sent to President Bush to sign into law.
	New publication, GAPscreener: An Automatic Tool for Screening Human Genetic Association Literature in PubMed Using the Support Vector Machine Technique,  published in the April 22 2008 issue of BMC Bioinformatics. Authors: Yu W, Clyne M, Dolan SM, Yesupriya A, Wulf A, Liu T, Khoury MJ, Gwinn M. The GAPscreener software can be downloaded free of charge from the HuGE Navigator Web site.
	Upcoming Public Health Grand Rounds: Strengthening the Public Health System to Advance Genomics, on April 29, 2008, in Ann Arbor, MI. Register for the live webcast,  or register to attend in person.
	What's New in HuGENet™ April 2008

• The following are headlines from on-line news articles published during the past week.
• The headlines and lead sentence are exactly as they appear in the popular press & do not necessarily reflect the opinions or recommendations of CDC.
• Free registration required for some articles.

Genetic aspects of Alzheimer disease
Bird TD
Genet Med 2008 Apr;10(4):231-9

Geriatric neurogenetics: oxymoron or reality?
Bird TD, et al.
Arch Neurol 2008 Apr;65(4):537-9

Gene polymorphisms/mutations relevant to abnormal spermatogenesis
Nuti F & Krausz C
Reprod Biomed Online 2008 Apr;16(4):504-13

Nutrigenetics and CVD: what does the future hold?
Lovegrove JA & Gitau R
Proc Nutr Soc 2008 May;67(2):206-13

BRCA1 and BRCA2 risk perceptions among African American women at increased risk for hereditary breast-ovarian cancer
Kessler L, et al.
Community Genet 2008;11(4):193-200

Advances in autism genetics: on the threshold of a new neurobiology
Abrahams BS & Geschwind DH
Nat Rev Genet 2008 May;9(5):341-55

Educating the general public about multifactorial genetic disease: applying a theory-based framework to understand current public knowledge
Smerecnik CM, et al.
Genet Med 2008 Apr;10(4):251-8

REASSESSING INSURERS' ACCESS TO GENETIC INFORMATION: GENETIC PRIVACY, IGNORANCE,  AND INJUSTICE
Feiring E
Bioethics 2007 Apr

Update of the Pompe disease mutation database with 107 sequence variants and a format for severity rating
Kroos M, et al.
Hum Mutat 2008 Apr

Pharmacogenetics: potential role in the treatment of diabetes and obesity
Vella A & Camilleri M
Expert Opin Pharmacother 2008 May;9(7):1109-19

Lung cancer epigenetics and genetics
Risch A & Plass C
Int J Cancer 2008 Apr

Genetic polymorphisms and head and neck cancer risk (Review)
Hiyama T, et al.
Int J Oncol 2008 May;32(5):945-73

Genetic approaches to addiction: genes and alcohol
Ducci F & Goldman D
Addiction 2008 Apr

 

Genetic diagnosis of primary immune deficiencies
Morra M, et al.
Immunol Allergy Clin North Am 2008 May;28(2):387-412

Psychological and Behavioural Impact of Genetic Testing Smokers for Lung Cancer Risk: A Phase II Exploratory Trial
Sanderson SC, et al.
J Health Psychol 2008 May;13(4):481-94

Screening for Familial Ovarian Cancer: Poor survival of BRCA1/2 related cancers
Evans GR, et al.
J Med Genet 2008 Apr

 

The family history: reemergence of an established tool
Hinton RB Jr
Crit Care Nurs Clin North Am 2008 Jun;20(2):149-58

Familial predisposition to cardiovascular risk and disease contributes to cardiovascular risk and disease interacting with other cardiovascular risk factors in diabetes-Implication for common soil (JDDM 14)
Yokoyama H, et al.
Atherosclerosis 2008 Mar

Screening participation in individuals with a family history of colorectal cancer: a review
Rees G, et al.
Eur J Cancer Care (Engl) 2008 May;17(3):221-32

Diagnosed with breast cancer while on a family history screening programme: an exploratory qualitative study
Clements A, et al.
Eur J Cancer Care (Engl) 2008 May;17(3):245-52

Articles that report on population prevalence of genotypes, gene-disease associations, gene-environment and gene-gene interactions and evaluation of genetic tests. For more information on HuGE, please visit the HuGENet™ home page

For the week ending April 23, 2008, there are HuGE articles in the following areas:

Infectious and Parasitic Diseases
Neoplasms
Endocrine, Nutritional and Metabolic Diseases
Diseases of the Blood and Blood-Forming Organs Disorders
Mental Disorders
Diseases of the Nervous System and Sense Organs
Diseases of the Circulatory System
Diseases of the Respiratory System
Diseases of the Digestive System
Diseases of the Genitourinary System
Complications of Pregnancy, Childbirth, and the Puerperium
Diseases of the Skin and Subcutaneous Tissue
Diseases of the Musculoskeletal System and Connective Tissue
Congenital Anomalies

For more information on HuGE, please visit the HuGENet™ home page