CDC's National Office of Public Health Genomics announces a new funding opportunity for genomics translation in education, surveillance, and policy interventions. The deadline for final applications is June 6, 2008.
	New publication, HuGE Watch: tracking trends and patterns of published studies of genetic association and human genome epidemiology in near-real time, published in the May 14, 2008 issue of The European Journal of Human Genetics. Authors: Yu W, Wulf A, Yesupriya A, Clyne M, Khoury MJ, Gwinn M.
	New report, Infrastructure to Monitor Utilization and Outcomes of Gene-based Applications: An Assessment, released by the Agency for Healthcare Research and Quality on May 21, 2008.
	New report, U.S. System of Oversight of Genetic Testing: A Response to the Charge of the Secretary of Health and Human Services,(2.1MB) released by the Secretary’s Advisory Committee on Genetics, Health, and Society in April 2008.
	HuGE What's New May 2008

• The following are headlines from on-line news articles published during the past week.
• The headlines and lead sentence are exactly as they appear in the popular press & do not necessarily reflect the opinions or recommendations of CDC.
• Free registration required for some articles.

Consumer acceptance of nutrigenomics-based personalised nutrition Ronteltap A, et al. Br J Nutr 2008 May:1-13

The molecular genetics of type 1 diabetes: new genes and emerging mechanisms
Ounissi-Benkalha H & Polychronakos C
Trends Mol Med 2008 May

Glucokinase (GCK) and other susceptibility genes for beta-cell dysfunction: the candidate approach
Gloyn AL, et al.
Biochem Soc Trans 2008 Jun;36(Pt 3):306-11

The power of independent types of genetic information to detect association in a  case-control study design
Won S & Elston RC
Genet Epidemiol 2008 May

Genetic polymorphisms of the RAS-cytokine pathway and chronic kidney disease
Wong C, et al.
Pediatr Nephrol 2008 May

Neuregulin 1 in neural development, synaptic plasticity and schizophrenia
Mei L & Xiong WC
Nat Rev Neurosci 2008 May

PGA: power calculator for case-control genetic association analyses
Menashe I, et al.
BMC Genet 2008 May;9(1):36

The importance of replication in gene-gene interaction studies: Multifactor Dimensionality Reduction applied to a two-stage breast cancer case-control study
Milne RL, et al.
Carcinogenesis 2008 May

Consumer acceptance of nutrigenomics-based personalised nutrition
Ronteltap A, et al.
Br J Nutr 2008 May:1-13

Genetics of premature myocardial infarction
Roberts R
Curr Atheroscler Rep 2008 Jun;10(3):186-93

Identifying cancer genes from cancer mutation profiles by cancer functions
Li Y, et al.
Sci China C Life Sci 2008 Jun;51(6):569-74

Genetic susceptibility to occupational exposures
Christiani DC, et al.
Occup Environ Med 2008 Jun;65(6):430-6; quiz 436, 397

Genetic association of cytokine DNA polymorphisms with head and neck cancer
Serefoglou Z, et al.
Oral Oncol 2008 May

CYP450 pharmacogenetics for personalizing cancer therapy
van Schaik RH
Drug Resist Updat 2008 May

The genetics of intervertebral disc degeneration.Associated genes
Kalichman L & Hunter DJ
Joint Bone Spine 2008 May

Interindividual variability in oral antidiabetic drug disposition and response: the role of drug transporter polymorphisms
Pacanowski MA, et al.
Expert Opin Drug Metab Toxicol 2008 May;4(5):529-44

UMD-USHbases: a comprehensive set of databases to record and analyse pathogenic mutations and unclassified variants in seven Usher syndrome causing genes
Baux D, et al.
Hum Mutat 2008 May

Thailand mutation and variation database (ThaiMUT)
Ruangrit U, et al.
Hum Mutat 2008 May

Promotion of Cancer Family History Awareness: Jameslink Cancer Risk Assessment Tool at Community Health Fairs
Kelly KM, et al.
J Genet Couns 2008 May

Racial Differences in Prostate Cancer Screening by Family History
Drake BF, et al.
Ann Epidemiol 2008 May

Timing of Familial Breast Cancer in Sisters
Rebora P, et al.
J Natl Cancer Inst 2008 May

Testicular Cancer and Genetics Knowledge Among Familial Testicular Cancer Family  Members
Peters JA, et al.
J Genet Couns 2008 May

 

Genomic medicine and developing countries: creating a room of their own
Seguin B, et al.
Nat Rev Genet 2008 Jun;9(6):487-93

Health Behaviors and Psychological Distress in Women Initiating BRCA1/2 Genetic Testing: Comparison with Control Population
Dorval M, et al.
J Genet Couns 2008 May

Association between temporal orientation and attitudes about BRCA1/2 testing among women of African descent with family histories of breast cancer
Edwards TA, et al.
Patient Educ Couns 2008 May

Uptake of genetic counselling and predictive DNA testing in hypertrophic cardiomyopathy
Christiaans I, et al.
Eur J Hum Genet 2008 May

 

A genome-wide association study identifies novel alleles associated with hair color and skin pigmentation
Han J, et al.
PLoS Genet 2008 May;4(5):e1000074

Common sequence variants on 20q11.22 confer melanoma susceptibility
Brown KM, et al.
Nat Genet 2008 May

Two newly identified genetic determinants of pigmentation in Europeans
Sulem P, et al.
Nat Genet 2008 May

Genome-wide association analysis with selective genotyping identifies candidate loci for adult height at 8q21.13 and 15q22.33-q23 in Mongolians
Kimura T, et al.
Hum Genet 2008 May

Articles that report on population prevalence of genotypes, gene-disease associations, gene-environment and gene-gene interactions and evaluation of genetic tests. For more information on HuGE, please visit the HuGENet™ home page

For the week ending May 21, 2008, there are HuGE articles in the following areas:

Infectious and Parasitic Diseases
Neoplasms
Endocrine, Nutritional and Metabolic Diseases
Diseases of the Blood and Blood-Forming Organs Disorders
Mental Disorders
Diseases of the Nervous System and Sense Organs
Diseases of the Circulatory System
Diseases of the Respiratory System
Diseases of the Digestive System
Diseases of the Genitourinary System
Complications of Pregnancy, Childbirth, and the Puerperium
Diseases of the Skin and Subcutaneous Tissue
Diseases of the Musculoskeletal System and Connective Tissue
Congenital Anomalies
Certain Conditions Originating in the Perinatal Period
Symptoms, Signs, and Ill-defined Conditions

For more information on HuGE, please visit the HuGENet™ home page