New evidence report,“Collection and Use of Cancer Family History in Primary Care,” released by the HHS Agency for Healthcare Research and Quality this month.
	New article, “The Continuum of Translation Research in Genomic Medicine: How Can We Accelerate the Appropriate Integration of Human Genome Discoveries into Health Care and Disease Prevention?,”  (148KB) published in the October 2007 issue of Genetics in Medicine. Authors: Khoury MJ, Gwinn M, Yoon PW, Dowling N, Moore CA, and Bradley L.

• The following are headlines from on-line news articles published during the past week.
• The headlines and lead sentence are exactly as they appear in the popular press & do not necessarily reflect the opinions or recommendations of CDC.
• Free registration required for some articles.

Bad Nature, Bad Nurture, and Testimony Regarding MAOA and SLC6A4 Genotyping at Murder Trials
Bernet W, et al.
J Forensic Sci 2007 Oct

Silent polymorphisms speak: how they affect pharmacogenomics and the treatment of cancer
Sauna ZE, et al.
Cancer Res 2007 Oct;67(20):9609-12

Genetic Factors in Diabetic Nephropathy
Freedman BI, et al.
Clin J Am Soc Nephrol 2007 Oct

Combining Association Tests across Multiple Genetic Markers in Case-Control Studies
Zhou H, et al.
Hum Hered 2007 Oct;65(3):166-74

Designing candidate gene and genome-wide case-control association studies
Zondervan KT & Cardon LR
Nat Protoc 2007;2(10):2492-501

Experiencing the genetic body: parents' encounters with pediatric clinical genetics
Raspberry K & Skinner D
Med Anthropol 2007 Oct-2007 Dec;26(4):355-91

Genetic counseling and clinical management of newly diagnosed breast cancer patients at genetic risk for BRCA germline mutations: perspective of a surgical oncologist
Silva E
Fam Cancer 2007 Oct

The Predominant Role of Surgery in the Prevention and New Trends in the Surgical  Treatment of Women With BRCA1/2 Mutations
Fatouros M, et al.
Ann Surg Oncol 2007 Oct

Copy Number Variants and Common Disorders: Filling the Gaps and Exploring Complexity in Genome-Wide Association Studies
Estivill X & Armengol L
PLoS Genet 2007 Oct;3(10):e190

Society of gynecologic oncologists education committee statement on risk assessment for inherited gynecologic cancer predispositions
Lancaster JM, et al.
Gynecol Oncol 2007 Nov;107(2):159-62

The effect of the plasminogen activator inhibitor-1 4G/5G polymorphism on the thrombotic risk
Tsantes AE, et al.
Thromb Res 2007 Oct

Development and pilot evaluation of novel genetic educational materials designed  for an underserved patient population
Lubitz RJ, et al.
Genet Test 2007 Fall;11(3):276-90

Perceptions of discrimination among persons who have undergone predictive testing for Huntington's disease
Penziner E, et al.
Am J Med Genet B Neuropsychiatr Genet 2007 Oct

Information Needs of Mothers Regarding Communicating BRCA1/2 Cancer Genetic Test  Results to Their Children
Tercyak KP, et al.
Genet Test 2007 Fall;11(3):249-55

Attitudes of Families Affected by Adrenoleukodystrophy toward Prenatal Diagnosis, Presymptomatic and Carrier Testing, and Newborn Screening
Schaller J, et al.
Genet Test 2007 Fall;11(3):296-302

Should Individuals Be Informed about Their Salt Sensitivity Status? First Indications of the Value of Testing for Genetic Predisposition to Low-Risk Conditions
Smerecnik CM, et al.
Genet Test 2007 Fall;11(3):307-14

Neonatal screening for sickle cell disease in Central Africa: a study of 1825 newborns with a new enzyme-linked immunosorbent assay test
Mutesa L, et al.
J Med Screen 2007;14(3):113-6

Genetic counseling for inherited thrombophilias
Varga EA
J Thromb Thrombolysis 2007 Oct

Ethnic Differences in Parental Perceptions of Genetic Testing for Deaf Infants
Palmer CG, et al.
J Genet Couns 2007 Oct

Living at Risk: Concealing Risk and Preserving Hope in Huntington Disease
Quaid KA, et al.
J Genet Couns 2007 Oct

Can we identify the high-risk patients to be screened? A genetic approach
Gammon A, et al.
Digestion 2007;76(1):7-19

 

A genetic history questionnaire-based system in primary prenatal care to screen for selected fetal disorders
Bradley LA, et al.
Genet Test 2007 Fall;11(3):291-5

Data reduction for prediction: A case study on robust coding of age and family history for the risk of having a genetic mutation
Steyerberg EW, et al.
Stat Med 2007 Oct 19

Articles that report on population prevalence of genotypes, gene-disease associations, gene-environment and gene-gene interactions and evaluation of genetic tests. For more information on HuGE, please visit the HuGENet™ home page

For the week ending October 25, 2007, there are HuGE articles in the following areas:

Gene Variant Frequency
Infectious and Parasitic Diseases
Neoplasms
Endocrine, Nutritional and Metabolic Diseases
Diseases of the Blood and Blood-Forming Organs Disorders
Mental Disorders
Diseases of the Nervous System and Sense Organs
Diseases of the Circulatory System
Diseases of the Respiratory System
Diseases of the Digestive System
Diseases of the Genitourinary System
Diseases of the Musculoskeletal System and Connective Tissue

For more information on HuGE, please visit the HuGENet™ home page