Histopathology:
Photomicrographs Showing Histopathological
Features Less Commonly Seen In Cases of HPS
Captions:
A. Lung showing extensive interstitial and alveolar fibrosis.
Note the increased interstitial cellularity with numerous fibroblasts.
B. Patchy areas of alveolar septal thickening and prominent hyaline membranes.
C. Higher magnification showing typical dense laminated hyaline membranes.
D. Alveolar septum showing prominent type II pneumocyte proliferation.
E. Abundant polymorphonuclear leukocytes fill alveolar spaces with focal destruction of
alveolar septa.
F. Higher power magnification showing the antraalveolar exudate
composed mainly of polymorphonuclear leukocytes, red blood cells, and fibrin.
Original magnifications: A & B, x 50; C, x 100; D,
x 158; E, x 50; F, x 158.
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This page last reviewed Tuesday, June 22, 2004
Special Pathogens Branch
Division of Viral and Rickettsial Diseases
National Center for Infectious Diseases
Centers for Disease Control and Prevention
U.S. Department of Health and Human Services
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