Ultrasound and X-Ray in Detecting Articular Cartilage Calcification - Full Text View

Sponsored by:	University Hospital, Limoges
Information provided by:	University Hospital, Limoges
ClinicalTrials.gov Identifier:	NCT00797537

Purpose

Prospective study with an echography of the 2 knees and radiography of the 2 knees (front and profile) for each patient. If found calcification on ultrasound further examination with ultrasound wrists, hips and shoulders.

Condition	Intervention
Chondrocalcinosis Articular Cartilage Calcification	Procedure: Echography

MedlinePlus related topics: Ultrasound X-Rays

Drug Information available for: X-Rays

U.S. FDA Resources

Study Type:	Interventional
Study Design:	Diagnostic, Non-Randomized, Open Label, Active Control, Single Group Assignment
Official Title:	Concordance Entre l'échographie du Genou et la Radiographie Standard Dans la détection Des Calcifications Dans le Cadre de la Chondrocalcinose Articulaire

Further study details as provided by University Hospital, Limoges:

Primary Outcome Measures:

Knee calcification detected by echography and radiography [ Time Frame: Day 1 ] [ Designated as safety issue: No ]

Secondary Outcome Measures:

Calcification description and other localisations finding [ Time Frame: Day 1 ] [ Designated as safety issue: No ]

Estimated Enrollment:	166
Study Start Date:	May 2008
Estimated Primary Completion Date:	May 2010 (Final data collection date for primary outcome measure)

Detailed Description:

Osteo-articular echography is currently recognized as an important development among rheumatologists.

Chondrocalcinosis, which can promote joint inflammation and cartilage degeneration, is highly prevalent in elderly subjects.

Osteo-articular echography is currently reconized as an important development among rheumatologists and can efficiently use to detect Chondrocalcinosis.

The aim of this study is to find a correlation between radiography and echography in detecting CPPD crystal deposition, on a sample of patients and more important with a new generation of ultrasound with a probe superficial performance.

166 patients will be enrolled in this trial and an echography and a radiography of the 2 knees (front and profile) will be done for each patient.

Ih the echography show a calcification, further exams with wrists, hips shoulders echographies will be conducted.

In case of liquid epanchement, analysis of the liquid will be carried in order to eliminate the differential diagnostic including septic arthritis

Eligibility

Ages Eligible for Study:	70 Years and older
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No

Criteria

Inclusion Criteria:

patient> 70 years
articular pathology of the knee
consent signed

Exclusion Criteria:

Not covered by social security

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00797537

Contacts

Contact: Carine Dufauret-Lombard, MD	0033555056855	carine.dufauret-lombard@chu-limoges.fr
Contact: Vergne-Salle Pascale, MD	0033555056855	pascale.vergne-salle@chu-limoges.fr

Locations

France
Service de Rhumatologie	Recruiting
Limoges, France, 87000
Contact: Carine Dufauret-Lombrad, MD 0033555056855 carine.dufauret-lombard@chu-limoges.fr
Principal Investigator: Carine DUFAURET-LOMBARD, MD
Sub-Investigator: Pascale VERGNE-SALLE, MD

Sponsors and Collaborators

University Hospital, Limoges

More Information

Responsible Party:	CHU de Limoges ( CHU de Limoges )
Study ID Numbers:	I07027/chondrocalcinose
Study First Received:	November 20, 2008
Last Updated:	November 24, 2008
ClinicalTrials.gov Identifier:	NCT00797537
Health Authority:	France: Direction Générale de la Santé

Keywords provided by University Hospital, Limoges:

Inflammation of bone and cartilage

Study placed in the following topic categories:

Calcinosis
Metabolic Diseases
Musculoskeletal Diseases
Chondrocalcinosis
Joint Diseases

Arthritis
Metabolic disorder
Osteitis
Inflammation

Additional relevant MeSH terms:

Calcium Metabolism Disorders

ClinicalTrials.gov processed this record on January 16, 2009