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Streptococcus mutans Search Results

Record: 1 of 1  
MiniMap IGR1672 IGR1671 IGR1673 IGR1669 IGR1677 IGR1675 IGR1670 IGR1676 IGR1668 SMu1938 SMu1939 rplI,rl9, - SMu1941 rs4,rpsD, - SMu1937 rpiA, - SMu1944 trmU, - SMu1945 dnaC, - SMu1940 gidA, - SMu1943 SMu1942 SMu1935 SMu1936 SMu1938 SMu1939 rplI,rl9, - SMu1941 rs4,rpsD, - SMu1937 rpiA, - SMu1944 trmU, - SMu1945 dnaC, - SMu1940 gidA, - SMu1943 SMu1942 SMu1935 SMu1936 SMu1939 rplI,rl9, - SMu1941 rs4,rpsD, - SMu1937 trmU, - SMu1945 dnaC, - SMu1940 gidA, - SMu1943 SMu1942 SMu1935 SMu1938 rpiA, - SMu1944 SMu1936


LANL Gene ID: SMu1941

GenBank Locus Tag: SMU.2139c

DNA Molecule Name:
1  

GenBank ID:
24380469

Gene Name:
rplI  rl9  

Definition:
50S ribosomal protein L9

Cellular Location:
Cytoplasm [Evidence]

Gene Start:
2002270

Gene Stop:
2001818

Gene Length:
453

Molecular Weight*:
16754

pI*:
10.50

Net Charge*:
10.48

EC:
 

Functional Class:
Protein synthesis; Ribosomal proteins: synthesis and modification  

Gene Ontology:
Biological process
  GO:0006412    translation

Cellular component
  GO:0005622    intracellular
  GO:0005840    ribosome

Molecular function
  GO:0003735    structural constituent of ribosome


Pathway: pathway table

Secondary Evidence:
Vorgias,C.E., Kingswell,A.J., Dauter,Z. and Wilson,K.S. Cloning, overexpression, purification and crystallisation of ribosomal protein L9 from Bacillus stearothermophilus. FEBS letters. 286 (1-2), 204-208 (1991) PubMed: 1864369
Hoffman,D.W., Davies,C., Gerchman,S.E., Kycia,J.H., Porter,S.J., White,S.W. and Ramakrishnan,V. Crystal structure of prokaryotic ribosomal protein L9: a bi-lobed RNA-binding protein. The EMBO journal. 13 (1), 205-212 (1994) PubMed: 8306963


Comment:
For other 'rpl' genes see SMu0639 (rplT); SMu0771 (rplU); SMu0152 (rplM);SMu0869 (rplJ); SMu0872 (rpl); SMu1175 (rplS); SMu1480 (rplA) and SMu1481 (rplK).

For other 'rl' genes see SMu1819.1 (rl36);SMu1909.1(rl32);SMu0108 (rl28);SMu1840 (rl3);SMu1839 (rl4); SMu1837 (rl22); SMu1835 (rl16); SMu1834 (rl29); SMu1832 (rl14); SMu1831 (rl24); SMu1830 (rl5); SMu1827 (rl6); SMu1826 (rl18); SMu1824 (rl30); SMu1823 (rl15) and SMu1816 (rl7).


From GenBank (gi:15672727):
This protein binds to the 23S RNA.



View in HOMD Genome Viewer

Blast Summary:  PSI-Blast Search
Many matches in gapped BLAST to 50S ribosomal protein L9; e.g. residues 1-150 are 61% similar to 50S ribosomal protein L9 of Streptococcus pyogenes (15675918); residues 1-149 are 37% similar to 50S ribosomal protein L9 of Bacillus subtilis (16081102).





The best hit to the Streptococcus agalactiae 2603 V/R genome is to SAG2140 (1e-43).


Top Blast Hits:  Updated monthly
Click here to view the entire PsiBlast results.
 gi|24380469|ref|NP_722424.1|  50S ribosomal protein L9 [Stre...   224   1e-57
 gi|146319814|ref|YP_001199526.1|  Ribosomal protein L9 [Stre...   193   2e-48
 gi|81097432|ref|ZP_00875715.1|  Ribosomal protein L9 [Strept...   192   3e-48
 gi|125719131|ref|YP_001036264.1|  50S ribosomal protein L9, ...   182   5e-45
 gi|71904530|ref|YP_281333.1|  50S ribosomal protein L9 [Stre...   177   2e-43
 gi|15675918|ref|NP_270092.1|  50S ribosomal protein L9 [Stre...   177   2e-43
 gi|19747017|ref|NP_608153.1|  50S ribosomal protein L9 [Stre...   177   2e-43
 gi|139474606|ref|YP_001129322.1|  50S ribosomal protein L9 [...   176   3e-43
 gi|50915200|ref|YP_061172.1|  50S ribosomal protein L9 [Stre...   176   4e-43
 gi|157075045|gb|ABV09728.1|  ribosomal protein L9 [Streptoco...   176   5e-43


InterPro Summary:  InterProScan

InterPro
IPR000244
Family
Ribosomal protein L9
PTHR21368 [1-150]T 9.300000484759621E-35 PTHR21368 Ribosomal_L9 Ribosomal_L9
PF01281 [1-48]T 1.2000011745814E-19 PF01281 Ribosomal_L9_N Ribosomal_L9_N
PF03948 [62-150]T 1.4999997758334102E-14 PF03948 Ribosomal_L9_C Ribosomal_L9_C
TIGR00158 [1-150]T 1.95509431411104E-37 TIGR00158 L9 L9
PS00651 [13-40]T 8.0E-5 PS00651 RIBOSOMAL_L9 RIBOSOMAL_L9
SSF55653 [56-150]T 1.3E-25 SSF55653 Ribosomal_L9 Ribosomal_L9
InterPro
IPR009027
Domain
Ribosomal protein L9 N-terminal-like
SSF55658 [1-55]T 1.2E-15 SSF55658 L9_N_like L9_N_like
noIPR
unintegrated
unintegrated
G3DSA:3.10.430.100 [60-147]T 2.90000354677958E-20 G3DSA:3.10.430.100 G3DSA:3.10.430.100 G3DSA:3.10.430.100
G3DSA:3.40.5.10 [1-59]T 3.09999945899376E-15 G3DSA:3.40.5.10 G3DSA:3.40.5.10 G3DSA:3.40.5.10
PTHR21368:SF17 [1-150]T 9.300000484759621E-35 PTHR21368:SF17 PTHR21368:SF17 PTHR21368:SF17


COGS Summary:  COGS Search
BeTs to 12 clades of COG0359
COG name: Ribosomal protein L9
Functional Class: J
The phylogenetic pattern of COG0359 is ----yqvcebrhujgpolinx
Number of proteins in this genome belonging to this COG is 1
Blocks Summary:  Blocks Search
***** IPB000244 (Ribosomal protein L9) with a combined E-value of 1.1e-31.
    IPB000244A    1-31
    IPB000244B    86-100
    IPB000244C    123-147


 ProDom Summary:  Protein Domain Search
Residues 1-104 are 37% similar to a (RIBOSOMAL 50S RRNA-BINDING PROTEOME) protein domain (PD003590 which is seen in Q9CHI6_LACLA.

Residues 84-148 are 38% similar to a (RIBOSOMAL 50S L9 RRNA-BINDING) protein domain (PD287380 which is seen in RL9_THEMA.


Paralogs:  Local Blast Search
SMu1941 has no significant similarity (blastp p-value < 1e-3) to any other gene in this genome.


Pfam Summary:  Pfam Search
Residues 1 to 52 (E-value = 3.1e-22) place SMu1941 in the Ribosomal_L9_N family which is described as Ribosomal protein L9, N-terminal domain (PF01281)
Residues 62 to 150 (E-value = 6.9e-20) place SMu1941 in the Ribosomal_L9_C family which is described as Ribosomal protein L9, C-terminal domain (PF03948)

 Top PDB Hits:
pdb|487D|K Chain K, Seven Ribosomal Proteins Fitted To A Cryo-E... 92 3e-020

Gene Protein Sequence:
MKVIFLADVKGKGKRGEVKEVSTGYAQNFLIKKNLAKEATKQAINELKGK
QKSEEKAQAELLAEAKAVKVKLEQESTLVQFSEKVGPDGRTFGSITSKKI
SEELNKQFGIKLDKRYIKLDHPIRTIGLIEIPVKLHKDIDGIIKLQIKEA


Gene Nucleotide Sequence:  Sequence Viewer
ATGAAAGTTATTTTTTTAGCAGATGTCAAAGGTAAAGGTAAGAGAGGGGA
AGTAAAAGAAGTTTCTACAGGTTATGCTCAGAATTTTTTAATCAAGAAAA
ATTTGGCTAAGGAAGCCACAAAACAAGCTATTAATGAGTTAAAGGGAAAG
CAAAAATCTGAAGAAAAAGCTCAAGCCGAACTTTTAGCTGAGGCTAAAGC
AGTTAAAGTTAAACTTGAACAAGAATCAACGCTTGTTCAATTCAGTGAAA
AGGTTGGTCCAGATGGTCGTACTTTTGGTTCTATTACAAGTAAAAAAATT
TCTGAAGAATTGAACAAACAATTTGGGATCAAACTGGATAAACGTTATAT
TAAATTAGATCATCCGATTCGAACAATTGGTTTAATTGAAATTCCTGTAA
AACTTCACAAAGATATTGATGGCATCATTAAACTTCAAATTAAAGAAGCT
TAA

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