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Streptococcus mutans Search Results

Record: 1 of 1  
MiniMap tRNA-Arg-2 tRNA-Gln-2 IGR941 IGR942 IGR939 IGR940 IGR943 IGR945 IGR944 SMu1095 pfk,pfkA, - SMu1090 rpsA, - SMu1097 dnaE, - SMu1091 SMu1096 yurY, - SMu1093 SMu1094 SMu1095 pfk,pfkA, - SMu1090 rpsA, - SMu1097 dnaE, - SMu1091 SMu1096 yurY, - SMu1093 SMu1094 SMu1095 pfk,pfkA, - SMu1090 rpsA, - SMu1097 dnaE, - SMu1091 SMu1096 yurY, - SMu1093 SMu1094 yhcF, - SMu1092 yhcF, - SMu1092


LANL Gene ID: SMu1093

GenBank Locus Tag: SMU.1194

DNA Molecule Name:
1  

GenBank ID:
24379622

Gene Name:
yurY  

Definition:
ABC transporter, ATP-binding protein

Cellular Location:
Cytoplasm, Membrane [Evidence]

Gene Start:
1137083

Gene Stop:
1137790

Gene Length:
708

Molecular Weight*:
26451

pI*:
6.40

Net Charge*:
-1.84

EC:
 

Functional Class:
Transport and binding proteins; ABC Superfamily: ATP-binding protein  

Gene Ontology:
Molecular function
  GO:0000166    nucleotide binding
  GO:0005524    ATP binding
  GO:0016887    ATPase activity
  GO:0017111    nucleoside-triphosphatase activity


Pathway: pathway table

Comment:
For other components see SMu1094 (MSD1).

View in HOMD Genome Viewer

Blast Summary:  PSI-Blast Search
Numerous matches in gapped BLAST to ABC transporter, ATP-binding proteins.
Residues 7-234 are 64% similar to 15675239| from S.pyogenes. Residues 5-235 are 56% similar to 15903602| from S.pneumoniae.





The best hit to the Streptococcus agalactiae 2603 V/R genome is to SAG1980 (3e-25).


Top Blast Hits:  Updated monthly
Click here to view the entire PsiBlast results.
 gi|24379622|ref|NP_721577.1|  putative ABC transporter, ATP-...   434   e-120
 gi|15675239|ref|NP_269413.1|  putative ABC transporter (ATP-...   315   1e-84
 gi|94990615|ref|YP_598715.1|  ABC transporter ATP-binding pr...   315   1e-84
 gi|25010981|ref|NP_735376.1|  hypothetical protein gbs0927 [...   315   2e-84
 gi|77408951|ref|ZP_00785674.1|  Unknown [Streptococcus agala...   313   4e-84
 gi|81096976|ref|ZP_00875295.1|  ABC transporter [Streptococc...   302   9e-81
 gi|146318194|ref|YP_001197906.1|  ABC-type multidrug transpo...   302   1e-80
 gi|157075100|gb|ABV09783.1|  ABC transporter, ATP-binding pr...   295   2e-78
 gi|125717689|ref|YP_001034822.1|  ABC-type multidrug transpo...   290   5e-77
 gi|156869747|gb|EDO63119.1|  hypothetical protein CLOLEP_001...   289   1e-76


InterPro Summary:  InterProScan

InterPro
IPR003439
Domain
ABC transporter related
PD000006 [131-173]T 0.0 PD000006 ABC_transporter ABC_transporter
PF00005 [33-206]T 5.000009099153149E-32 PF00005 ABC_tran ABC_tran
PS50893 [8-230]T 0.0 PS50893 ABC_TRANSPORTER_2 ABC_TRANSPORTER_2
InterPro
IPR003593
Domain
AAA+ ATPase, core
SM00382 [32-207]T 3.60000000000011E-11 SM00382 AAA AAA
noIPR
unintegrated
unintegrated
G3DSA:3.40.50.300 [7-220]T 1.7999975402237804E-44 G3DSA:3.40.50.300 G3DSA:3.40.50.300 G3DSA:3.40.50.300
PTHR19222 [8-232]T 9.90001804798338E-60 PTHR19222 PTHR19222 PTHR19222
PTHR19222:SF16 [8-232]T 9.90001804798338E-60 PTHR19222:SF16 PTHR19222:SF16 PTHR19222:SF16
SSF52540 [6-222]T 7.5E-51 SSF52540 SSF52540 SSF52540


COGS Summary:  COGS Search
BeTs to 12 clades of COG1131
COG name: ABC-type multidrug transport system, ATPase component
Functional Class: R
The phylogenetic pattern of COG1131 is AmTKy-VCEBR-uJ-pol--x
Number of proteins in this genome belonging to this COG is 14
Blocks Summary:  Blocks Search
***** IPB001140 (ABC transporter transmembrane region) with a combined E-value of 1.1e-22.
    IPB001140A    22-68
    IPB001140B    128-166


 ProDom Summary:  Protein Domain Search
Residues 5-229 are 22% similar to a (C24F3.5) protein domain (PD218211 which is seen in Q21213_CAEEL.

Residues 81-169 are 24% similar to a (ATP-BINDING PROTEOME COMPLETE ABC) protein domain (PD353124 which is seen in Q9K9J8_BACHD.

Residues 177-234 are 36% similar to a (ATP-BINDING PROTEOME COMPLETE ABC) protein domain (PD052760 which is seen in Q9ZK06_HELPJ.

Residues 79-162 are 30% similar to a (PROTEOME ATP-BINDING COMPLETE ABC) protein domain (PD395354 which is seen in Q9PD02_XYLFA.

Residues 79-220 are 22% similar to a (PROTEOME BINDING COMPLETE ABC) protein domain (PD398054 which is seen in Q9CDL6_LACLA.

Residues 131-173 are 58% similar to a (ATP-BINDING TRANSPORT ABC TRANSPORTER COMPLETE PROTEOME) protein domain (PD000006 which is seen in Q9ZK06_HELPJ.


Paralogs:  Local Blast Search
SMu1093 is paralogously related (blast p-value < 1e-3) to SMu0976, SMu0950, SMu0666, SMu0335, SMu0374, SMu1649, SMu0596, SMu0218, SMu0944, SMu1410, SMu1023, SMu0216, SMu0390, SMu1079, SMu1380, SMu1518, SMu0418, SMu1003, SMu1920, SMu0849, SMu1949, SMu0907, SMu0258, SMu0517, SMu1545, SMu1064, SMu1050, SMu1710, SMu0916, SMu0164, SMu1068, SMu1959, SMu0731, SMu1065, SMu1950, SMu0884, SMu1517, SMu0971, SMu1757, SMu0824, SMu1288, SMu0752, SMu1246, SMu1231, SMu0805, SMu0475, SMu0823, SMu1210, SMu0594, SMu1037, SMu0836, SMu1036, SMu1762, SMu1724, SMu0235, SMu1001, SMu0786, SMu1811, SMu1202, SMu1306, SMu1751, SMu0224, SMu0986, SMu0234, SMu0825, SMu1316, SMu1428, SMu0024, SMu0837, SMu0476, and SMu0729, all ABC-related ATP binding proteins.


Pfam Summary:  Pfam Search
Residues 33 to 206 (E-value = 2.9e-34) place SMu1093 in the ABC_tran family which is described as ABC transporter (PF00005)

 Top PDB Hits:
No significant hits to the NCBI PDB database.

Gene Protein Sequence:
MTEQLPLLQLHHITKKFGNKLALDDISLKLPKGKIIGLLGPNGSGKTTLI
KLANGLLQPTAGEIVINGLRPCPETKSLISYLPDTSYLSDKMKVHDILKL
FEDFYVDFDRQKAEQLLEDLAIAQSEKLKNLSKGNKEKVQLILVMSRKAK
LYILDEPIGGVDPAARDYILKTIINNYSEDASVLISTHLISDIEQVLDEV
IFINQGKIVLQENVDDLREQYAQSIDHIFREKFRA

Gene Nucleotide Sequence:  Sequence Viewer
ATGACAGAACAACTGCCCTTATTACAATTACATCATATTACTAAGAAGTT
TGGAAACAAGCTAGCTCTTGATGATATTTCTTTAAAATTACCAAAAGGTA
AAATAATTGGACTGTTGGGACCAAATGGAAGCGGTAAGACGACACTGATT
AAATTAGCTAATGGACTGTTACAACCTACTGCAGGTGAAATTGTGATTAA
CGGACTCAGACCTTGTCCTGAAACAAAATCGCTCATTTCCTATCTTCCCG
ATACCAGCTATTTAAGTGATAAAATGAAGGTCCATGACATTTTAAAACTA
TTTGAAGATTTCTATGTTGATTTTGATAGGCAAAAAGCCGAACAATTACT
GGAAGATTTAGCCATTGCTCAAAGCGAAAAATTAAAAAATCTTTCTAAAG
GAAACAAGGAAAAGGTTCAGCTTATTCTGGTTATGAGTCGCAAAGCAAAA
CTTTACATTTTGGATGAACCCATTGGTGGTGTTGATCCAGCTGCACGTGA
TTATATTTTAAAAACAATTATTAATAACTACTCAGAAGATGCATCTGTTC
TTATTTCAACTCATTTAATTTCGGATATTGAGCAGGTTTTAGATGAAGTT
ATTTTTATCAACCAAGGAAAGATTGTTTTACAAGAAAATGTAGATGATTT
GCGTGAACAATACGCACAATCAATCGATCACATTTTTAGAGAGAAATTTA
GAGCCTAG

Los Alamos National Laboratory • Est 1943

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