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Streptococcus mutans Search Results

Record: 1 of 1  
MiniMap IGR207 IGR206 IGR205 IGR209 IGR210 IGR204 IGR208 SMu0237 dacA, - SMu0230 SMu0236 oppB, - SMu0232 argF,arcB, - SMu0238 oppC, - SMu0233 oppD,amiE, - SMu0234 oppA, - SMu0231 SMu0237 dacA, - SMu0230 SMu0236 oppB, - SMu0232 argF,arcB, - SMu0238 oppC, - SMu0233 oppD,amiE, - SMu0234 oppA, - SMu0231 SMu0237 dacA, - SMu0230 SMu0236 oppB, - SMu0232 argF,arcB, - SMu0238 oppC, - SMu0233 oppD,amiE, - SMu0234 oppA, - SMu0231 oppF, - SMu0235 oppF, - SMu0235


LANL Gene ID: SMu0234

GenBank Locus Tag: SMU.258

DNA Molecule Name:
1  

GenBank ID:
24378766

Gene Name:
oppD  amiE  

Definition:
oligopeptide ABC transporter, ATP-binding

Cellular Location:
Cytoplasm, Membrane [Evidence]

Gene Start:
247543

Gene Stop:
248595

Gene Length:
1053

Molecular Weight*:
39159

pI*:
5.60

Net Charge*:
-9.84

EC:
 

Functional Class:
Transport and binding proteins; ABC Superfamily: ATP-binding protein  

Gene Ontology:
Biological process
  GO:0015833    peptide transport

Molecular function
  GO:0000166    nucleotide binding
  GO:0005524    ATP binding
  GO:0015197    peptide transporter activity
  GO:0016887    ATPase activity
  GO:0017111    nucleoside-triphosphatase activity


Pathway: pathway table

Comment:
For other components see SMu0235 (NBD1); SMu0233 (MSD1); SMu0232 (MSD2) and SMu0231 (SBP1).

For other 'opp' genes see SMu0231 (oppA); SMu0232 (oppB); SMu0233 (oppC) and SMu0235 (oppF).



View in HOMD Genome Viewer

Blast Summary:  PSI-Blast Search
Matches in gapped BLAST to oligopeptide ABC transporter ATP-binding proteins. Residues 1-347 are 73% similar to gi14289333 from L.lactis lactis. Residues 4-343 are 67% similar to gi8131708 from L.monocytogenes.





The best hit to the Streptococcus agalactiae 2603 V/R genome is to SAG0151 (1e-166).


Top Blast Hits:  Updated monthly
Click here to view the entire PsiBlast results.
 gi|24378766|ref|NP_720721.1|  putative oligopeptide ABC tran...   707   0.0  
 gi|22536336|ref|NP_687187.1|  oligopeptide ABC transporter, ...   570   e-161
 gi|77409724|ref|ZP_00786385.1|  oligopeptide ABC transporter...   552   e-155
 gi|116619002|ref|YP_819373.1|  ABC-type dipeptide/oligopepti...   542   e-152
 gi|125623235|ref|YP_001031718.1|  dipeptide transport ATP-bi...   535   e-150
 gi|15672329|ref|NP_266503.1|  oligopeptide ABC trasporter AT...   534   e-150
 gi|116511206|ref|YP_808422.1|  ABC-type dipeptide/oligopepti...   533   e-150
 gi|118586254|ref|ZP_01543712.1|  ABC-type oligopeptide trans...   508   e-142
 gi|116490886|ref|YP_810430.1|  ABC-type dipeptide/oligopepti...   507   e-142
 gi|28378030|ref|NP_784922.1|  oligopeptide ABC transporter, ...   499   e-139


InterPro Summary:  InterProScan

InterPro
IPR003439
Domain
ABC transporter related
PD000006 [157-198]T 0.0 PD000006 ABC_transporter ABC_transporter
PF00005 [36-232]T 9.19998414420311E-56 PF00005 ABC_tran ABC_tran
PS50893 [7-256]T 0.0 PS50893 ABC_TRANSPORTER_2 ABC_TRANSPORTER_2
InterPro
IPR003593
Domain
AAA+ ATPase, core
SM00382 [35-233]T 4.1999999999999997E-16 SM00382 AAA AAA
InterPro
IPR010066
Domain
Oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal
TIGR01727 [233-319]T 1.7879684994716904E-22 TIGR01727 oligo_HPY oligo_HPY
InterPro
IPR013563
Domain
Oligopeptide/dipeptide ABC transporter, C-terminal
PF08352 [235-299]T 1.3999989204989E-24 PF08352 oligo_HPY oligo_HPY
noIPR
unintegrated
unintegrated
G3DSA:3.40.50.300 [1-265]T 3.60002015030994E-74 G3DSA:3.40.50.300 G3DSA:3.40.50.300 G3DSA:3.40.50.300
PTHR19222 [7-323]T 0.0 PTHR19222 PTHR19222 PTHR19222
PTHR19222:SF28 [7-323]T 0.0 PTHR19222:SF28 PTHR19222:SF28 PTHR19222:SF28
SSF52540 [6-280]T 1.5E-66 SSF52540 SSF52540 SSF52540


COGS Summary:  COGS Search
BeTs to 10 clades of COG0444
COG name: ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component
Functional Class: E,P
The phylogenetic pattern of COG0444 is a-TKyqV-EB-Hujgpo-IN-
Number of proteins in this genome belonging to this COG is 1
Blocks Summary:  Blocks Search
***** IPB001140 (ABC transporter transmembrane region) with a combined E-value of 2.1e-23.
    IPB001140A    25-71
    IPB001140B    153-191
    IPB001140C    209-238


 ProDom Summary:  Protein Domain Search
Residues 199-238 are 75% similar to a (ATP-BINDING TRANSPORT COMPLETE PROTEOME ABC TRANSPORTER) protein domain (PD000079 which is seen in Q9F5U3_BACTU.

Residues 123-187 are 46% similar to a (ABC TRANSPORTER) protein domain (PD055062 which is seen in Q50241_METMA.

Residues 200-252 are 43% similar to a (ATP-BINDING PROTEOME COMPLETE TRANSPORT) protein domain (PD402931 which is seen in Q9KUA7_VIBCH.

Residues 6-69 are 39% similar to a (ATP-BINDING SAPD PEPTIDE TRANSPORT) protein domain (PD028306 which is seen in Q9KWT0_VIBAL.

Residues 282-336 are 67% similar to a (TRANSPORT ATP-BINDING OLIGOPEPTIDE) protein domain (PD050924 which is seen in Q9LAT4_LISMO.

Residues 93-145 are 51% similar to a (ATP-BINDING TRANSPORT COMPLETE PROTEOME TRANSPORTER ABC) protein domain (PD007166 which is seen in Q9ZMD5_HELPJ.

Residues 201-256 are 48% similar to a (ATP-BINDING TRANSPORT ABC TRANSPORTER) protein domain (PD019551 which is seen in O25032_HELPY.

Residues 93-142 are 44% similar to a (ATP-BINDING TRANSPORT PROTEOME COMPLETE) protein domain (PD261527 which is seen in Q9ZMD4_HELPJ.

Residues 201-279 are 35% similar to a (SAPD TRANSPORT ATP-BINDING PEPTIDE) protein domain (PD407079 which is seen in O86190_ERWCH.

Residues 240-280 are 73% similar to a (ATP-BINDING TRANSPORT PROTEOME COMPLETE) protein domain (PD029971 which is seen in Q9CIK9_LACLA.

Residues 82-127 are 76% similar to a (ATP-BINDING TRANSPORT COMPLETE PROTEOME) protein domain (PD332659 which is seen in Q9CIK9_LACLA.

Residues 240-278 are 65% similar to a (ATP-BINDING TRANSPORT PROTEOME) protein domain (PD253984 which is seen in OPPD_BACSU.

Residues 98-252 are 29% similar to a (ABC-BINDING PROTEOME RELATED OLIGOPEPTIDE) protein domain (PD077779 which is seen in Q9HIQ1_THEAC.

Residues 26-80 are 78% similar to a (ATP-BINDING TRANSPORT ABC TRANSPORTER COMPLETE PROTEOME) protein domain (PD000005 which is seen in Q9CIK9_LACLA.

Residues 209-278 are 47% similar to a (ATP-BINDING TRANSPORT PEPTIDE PROTEOME) protein domain (PD259958 which is seen in Q9HLF8_THEAC.

Residues 157-198 are 88% similar to a (ATP-BINDING TRANSPORT ABC TRANSPORTER COMPLETE PROTEOME) protein domain (PD000006 which is seen in Q9CIK9_LACLA.

Residues 88-153 are 53% similar to a (ATP-BINDING TRANSPORT PROTEOME COMPLETE ABC OLIGOPEPTIDE) protein domain (PD000720 which is seen in Q9WXR4_THEMA.


Paralogs:  Local Blast Search
SMu0234 is paralogously related (blast p-value < 1e-3) to SMu0235, SMu1762, SMu0517, SMu0731, SMu1288, SMu1068, SMu0971, SMu0218, SMu0418, SMu1380, SMu1003, SMu1751, SMu1246, SMu1231, SMu0884, SMu1950, SMu1036, SMu0916, SMu0786, SMu0849, SMu1037, SMu1079, SMu1949, SMu1920, SMu1210, SMu0805, SMu0594, SMu0216, SMu1428, SMu1517, SMu1757, SMu0390, SMu0907, SMu0976, SMu1518, SMu1001, SMu0950, SMu0475, SMu1316, SMu0258, SMu1064, SMu1023, SMu1710, SMu0335, SMu1410, SMu0374, SMu0476, SMu1649, SMu0837, SMu0944, SMu0825, SMu0824, SMu1811, SMu0596, SMu0987, SMu0823, SMu0836, SMu1065, SMu0164, SMu1050, SMu0986, SMu1724, SMu0729, SMu0752, SMu0224, SMu0666, SMu1093, SMu1959, SMu0024, SMu1545, and SMu1306, all ATP-binding proteins.


Pfam Summary:  Pfam Search
Residues 36 to 232 (E-value = 9.6e-59) place SMu0234 in the ABC_tran family which is described as ABC transporter (PF00005)

 Top PDB Hits:
pdb1G291 Chain 1, Malk >gi12084695pdb1G292 Chain 2, Malk 123 2e-029
pdb1B0UA Chain A, Atp-Binding Subunit Of The Histidine Permea... 121 2e-028

Gene Protein Sequence:
MSKEKILQVNNLHVNFHTYAGEVKAIRDVSFYLEKGETLAIVGESGSGKS
VTTRTLMGLSAKNAEIFGDIEFKGHNLNDLKEEDWVHIRGNDISMIFQDP
MTSLDPTMRIGLQIAEPIIKHEKVTKKEALKRALDMMEKVGIPNAQEHIN
DYPHQWSGGMRQRAVIAIALATNPEILVADEPTTALDVTIQAQILHLMKE
IQKNTDSSIIFITHDLGVVAGMADRVAVMYAGKIVEYGTVDEVFYNPQHP
YTWGLLNSMPTTNTASGSLHSIPGTPPDLLQPPQGDAFAPRNEFALDIDL
KEEPPFFKVSDSHYAATWLLDDRAPKITPPERILQRWEKWKSLQGEKHND


Gene Nucleotide Sequence:  Sequence Viewer
ATGAGTAAGGAAAAAATTTTACAAGTCAATAACCTCCATGTCAATTTTCA
TACCTATGCAGGTGAAGTAAAAGCTATTCGCGATGTTAGTTTTTATTTAG
AAAAAGGGGAAACGCTGGCTATTGTTGGCGAATCTGGTTCTGGAAAGTCG
GTAACCACACGAACTTTAATGGGGTTGTCAGCAAAGAATGCTGAGATTTT
CGGAGATATTGAGTTTAAGGGACACAATCTAAATGATTTGAAGGAAGAAG
ACTGGGTTCATATTCGCGGAAATGATATTTCCATGATTTTCCAAGATCCT
ATGACAAGTTTGGATCCAACCATGCGTATTGGCCTTCAAATTGCTGAACC
TATTATCAAGCATGAAAAAGTAACTAAAAAAGAAGCTCTTAAGCGGGCTC
TTGACATGATGGAAAAGGTTGGTATTCCCAATGCGCAAGAACACATCAAC
GATTATCCTCACCAGTGGTCAGGCGGTATGCGCCAGCGCGCTGTCATAGC
TATTGCTTTGGCAACTAATCCTGAAATCCTTGTTGCAGATGAACCAACGA
CGGCTCTTGATGTTACCATTCAAGCACAAATTCTTCATTTAATGAAAGAA
ATCCAAAAGAATACTGACTCTTCCATTATCTTTATCACTCATGATTTGGG
TGTCGTTGCAGGTATGGCAGACCGTGTTGCTGTTATGTATGCAGGCAAGA
TTGTGGAATATGGTACAGTAGATGAGGTTTTCTACAACCCACAGCATCCC
TACACTTGGGGGCTTCTCAATTCGATGCCTACAACTAATACAGCTTCAGG
CAGTTTGCATTCAATTCCCGGAACACCGCCTGACTTGTTGCAGCCCCCTC
AAGGAGATGCTTTTGCTCCAAGAAATGAATTCGCTCTTGATATTGATCTT
AAGGAGGAGCCGCCATTTTTTAAAGTTAGTGATTCACATTATGCTGCTAC
TTGGCTGTTAGATGATCGTGCTCCTAAGATTACTCCGCCGGAAAGAATTT
TGCAGCGTTGGGAAAAATGGAAGAGCTTACAGGGAGAAAAGCATAATGAC
TGA

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