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Streptococcus mutans Search Results

Record: 1 of 1  
MiniMap tRNA-Ala-5 tRNA-Asn-1 rRNA-5S-5 rRNA-16S-5 rRNA-23S-5 IGR1557 IGR1559 IGR1556 IGR1558 IGR1560 adcR,zitR, - SMu1812 comX, - SMu1814 adcB, - SMu1810 ipk,ispE, - SMu1813 tyrS, - SMu1809 adcR,zitR, - SMu1812 comX, - SMu1814 adcB, - SMu1810 ipk,ispE, - SMu1813 tyrS, - SMu1809 adcR,zitR, - SMu1812 comX, - SMu1814 adcB, - SMu1810 ipk,ispE, - SMu1813 adcC, - SMu1811 adcC, - SMu1811 tyrS, - SMu1809


LANL Gene ID: SMu1814

GenBank Locus Tag: SMU.1997c

DNA Molecule Name:
1  

GenBank ID:


Gene Name:
comX  

Definition:
competence-specific sigma factor

Cellular Location:
Cytoplasm [Evidence]

Gene Start:
1872503

Gene Stop:
1872021

Gene Length:
483

Molecular Weight*:
19590

pI*:
6.50

Net Charge*:
-1.07

EC:
 

Functional Class:
Cellular processes; DNA transformation  

Gene Ontology:

Pathway: pathway table

Primary Evidence:
Aspiras MB, Ellen RP, Cvitkovitch DG.
ComX activity of Streptococcus mutans growing in biofilms.
FEMS Microbiol Lett. 2004 Sep;238(1):167-74.
PMID: 15336418

Comment:
For other 'com' genes see SMu0567 (comEA); SMu0568 (comEC); SMu0138 (comR);SMu0258 (comA); SMu0259 (comB);SMu1804 (comYA);SMu1803 (comYB); SMu1802 (comYC);SMu1801 (comYD); SMu0451 (comF); SMu0452 (comFC); SMu0490 (comC); SMu1782 (comA);SMu1684 (comEB);SMu1710 (comA); SMu1739 (comC) and SMu1740 (comD).



View in HOMD Genome Viewer

Blast Summary:  PSI-Blast Search
Few moderate matches in gapped BLAST to competence-specific global transcription modulator; residues 1-160 are 43% similar to competence protein of Streptococcus pyogenes (gi15674470); residues 8-157 are 46% similar to transcriptional regulator ComX1 of Streptococcus pneumoniae (gi15899963).





The best hit to the Streptococcus agalactiae 2603 V/R genome is to SAG0091 (1e-39).


Top Blast Hits:  Updated monthly
Click here to view the entire PsiBlast results.
 gi|24380340|ref|NP_722295.1|  putative ComX1, transcriptiona...   273   3e-72
 gi|25010165|ref|NP_734560.1|  hypothetical protein gbs0090 [...   150   2e-35
 gi|28895138|ref|NP_801488.1|  putative competence protein (C...   139   5e-32
 gi|139473112|ref|YP_001127827.1|  putative competence-specif...   138   8e-32
 gi|19745426|ref|NP_606562.1|  putative competence protein [S...   138   1e-31
 gi|50913633|ref|YP_059605.1|  Competence-specific sigma fact...   138   1e-31
 gi|15674470|ref|NP_268644.1|  putative competence protein [S...   138   1e-31
 gi|19746823|ref|NP_607959.1|  putative competence protein [S...   137   2e-31
 gi|71902917|ref|YP_279720.1|  competence-specific sigma fact...   137   3e-31
 gi|21909756|ref|NP_664024.1|  putative transcriptional regul...   135   5e-31


InterPro Summary:  InterProScan

InterPro
IPR013325
Domain
RNA polymerase sigma factor, region 2
SSF88946 [2-97]T 6.800000000000001E-5 SSF88946 Sigma_r2 Sigma_r2


COGS Summary:  COGS Search
No hits to the COGs database.
Blocks Summary:  Blocks Search
No significant hits to the Blocks database.

 ProDom Summary:  Protein Domain Search
Residues 18-144 are 48% similar to a (PROTEOME COMPLETE REGULATOR COMPETENCE) protein domain (PD303084 which is seen in Q9R2W8_STRPN.


Paralogs:  Local Blast Search
SMu1814 has no significant similarity (blastp p-value < 1e-3) to any other gene in this genome.


Pfam Summary:  Pfam Search
No significant hits to the Pfam 11.0 database

 Top PDB Hits:
No significant hits to the NCBI PDB database.

Gene Protein Sequence:
MEEDFEIVFNKVKPIVWKLSRYYFIKMWTREDWQQEGMLILHQLLREHPE
LEEDDTKLYIYFKTRFSNYIKDVLRQQESQKRRFNRMSYEEVGEIEHCLS
SGGMQLDEYILFRDSLLAYKQGLSTEKQELFERLVAGEHFLGRQSMLKDL
RKKLSDFKEK

Gene Nucleotide Sequence:  Sequence Viewer
ATGGAAGAAGATTTTGAAATTGTTTTTAATAAGGTTAAGCCAATTGTATG
GAAATTAAGCCGTTATTACTTTATTAAAATGTGGACTCGTGAAGATTGGC
AACAAGAGGGAATGTTGATTTTGCACCAATTATTAAGGGAACATCCAGAA
TTAGAAGAGGATGATACAAAATTGTATATCTATTTTAAGACACGTTTTTC
TAATTACATTAAAGATGTTTTGCGTCAGCAAGAAAGTCAGAAACGTCGTT
TTAATAGAATGTCTTATGAAGAAGTCGGTGAGATTGAACACTGTTTGTCA
AGTGGCGGTATGCAATTGGATGAATATATTTTATTTCGTGATAGTTTGCT
TGCATATAAACAAGGTCTGAGTACTGAAAAGCAAGAGCTGTTTGAGCGCT
TGGTAGCAGGAGAGCACTTTTTGGGAAGGCAAAGTATGCTGAAAGATTTA
CGTAAAAAATTAAGTGATTTTAAGGAAAAATAG

Los Alamos National Laboratory • Est 1943

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