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Streptococcus mutans Search Results

Record: 1 of 1  
MiniMap IGR401 IGR395 IGR398 IGR399 IGR402 IGR397 IGR400 IGR403 IGR396 SMu0450 SMu0456 cysK, - SMu0449 yfiA, - SMu0453 mipB,talC, - SMu0447 dam,dpnM, - SMu0457 SMu0454 gldA, - SMu0448 comFA, - SMu0451 SMu0455 SMu0450 SMu0456 cysK, - SMu0449 yfiA, - SMu0453 mipB,talC, - SMu0447 dam,dpnM, - SMu0457 SMu0454 gldA, - SMu0448 comFA, - SMu0451 SMu0455 SMu0450 SMu0456 cysK, - SMu0449 yfiA, - SMu0453 mipB,talC, - SMu0447 dam,dpnM, - SMu0457 SMu0454 gldA, - SMu0448 comFA, - SMu0451 SMu0455 comFC, - SMu0452 comFC, - SMu0452


LANL Gene ID: SMu0452

GenBank Locus Tag: SMU.499

DNA Molecule Name:
1  

GenBank ID:
24378983

Gene Name:
comFC  

Definition:
late competence protein required for DNA uptake

Cellular Location:
Cytoplasm [Evidence]

Gene Start:
468416

Gene Stop:
469081

Gene Length:
666

Molecular Weight*:
26002

pI*:
9.10

Net Charge*:
10.25

EC:
 

Functional Class:
Cellular processes; Competence  

Gene Ontology:

Pathway: pathway table

Comment:
For other 'com' genes see SMu0567 (comEA); SMu0568 (comEC); SMu0138 (comR);SMu1814 (comX1); SMu0258 (comA);SMu0259 (comB);SMu1804 (comYA);SMu1803 (comYB);SMu1802 (comYC); SMu1801 (comYD); SMu0451 (comF); SMu0490 (comC); SMu1782 (comA);SMu1684 (comEB);SMu1710 (comA); SMu1739 (comC) and SMu1740 (comD).

Although associated with comF function, this protein does not appear to be paralogous to SMu0451, a predicted comF.



View in HOMD Genome Viewer

Blast Summary:  PSI-Blast Search
Matches in gapped BLAST to comF-related proteins and to proteins involved in DNA uptake. Residues 1-221 are 44% similar to 15902014, a predicted comF protein from S.pneumoniae and are 45% similar to 15673071, a predicted comFC protein from L.lactis.





The best hit to the Streptococcus agalactiae 2603 V/R genome is to SAG0337 (1e-54).


Top Blast Hits:  Updated monthly
Click here to view the entire PsiBlast results.
 gi|24378983|ref|NP_720938.1|  putative late competence prote...   434   e-120
 gi|81177050|ref|ZP_00875952.1|  putative late competence pro...   223   7e-57
 gi|125718634|ref|YP_001035767.1|  Late competence protein, p...   223   7e-57
 gi|157075404|gb|ABV10087.1|  competence protein ComFC [Strep...   207   3e-52
 gi|25010399|ref|NP_734794.1|  hypothetical protein gbs0325 [...   197   3e-49
 gi|22536520|ref|NP_687371.1|  competence protein F, putative...   195   2e-48
 gi|77413324|ref|ZP_00789519.1|  putative competence protein ...   193   6e-48
 gi|149007749|ref|ZP_01831358.1|  competence protein ComF, pu...   189   7e-47
 gi|15902014|ref|NP_346618.1|  competence protein ComF, putat...   189   9e-47
 gi|15904053|ref|NP_359603.1|  Involved in transformation (co...   187   4e-46


InterPro Summary:  InterProScan

noIPR
unintegrated
unintegrated
SSF53271 [44-221]T 4.3E-25 SSF53271 SSF53271 SSF53271


COGS Summary:  COGS Search
BeTs to 8 clades of COG1040
COG name: Predicted amidophosphoribosyltransferases
Functional Class: R
The phylogenetic pattern of COG1040 is -----qvcebrh----ol---
Number of proteins in this genome belonging to this COG is 1
Blocks Summary:  Blocks Search
No significant hits to the Blocks database.

 ProDom Summary:  Protein Domain Search
No significant hits to the ProDom database.

Paralogs:  Local Blast Search
SMu0452 has no significant similarity (blastp p-value < 1e-3) to any other gene in this genome.


Pfam Summary:  Pfam Search
No significant hits to the Pfam 11.0 database

 Top PDB Hits:
No significant hits to the NCBI PDB database.

Gene Protein Sequence:
MNCLICHLPFESKYYFYSIFFLKTSRDFVCPPCFAKFQFVSEKHCLNCYK
EGEGDICQDCHKWQNLKKEVHHKALFCYNQAMKDYFSAYKFQGDYLLRKV
FIKPIKEALREYTNYTLVPIPLSSSSLENRGFNQVQAFLDEAKLSYHDLL
GKEDGSVKQSSKTRQERLKTQQNFYLRKHKELPDKVMLVDDIYTTGMTIQ
LASQLLRENGVKTIKSFSLAR

Gene Nucleotide Sequence:  Sequence Viewer
ATGAACTGTCTCATTTGTCACTTGCCTTTTGAGAGTAAATATTATTTCTA
TTCTATTTTCTTCTTGAAAACTTCAAGAGATTTTGTTTGCCCACCTTGCT
TTGCGAAATTTCAATTCGTATCTGAAAAACATTGCCTAAATTGTTATAAG
GAGGGAGAAGGAGATATCTGTCAAGATTGCCACAAATGGCAAAATCTCAA
AAAGGAGGTTCATCACAAGGCTCTCTTTTGTTACAATCAAGCTATGAAAG
ATTATTTCAGTGCTTACAAATTTCAAGGGGATTATCTTTTAAGAAAGGTC
TTTATAAAGCCTATTAAAGAAGCCTTAAGAGAGTATACTAATTATACTTT
GGTTCCCATTCCACTCAGCTCTTCAAGTTTAGAGAATCGTGGTTTTAATC
AAGTGCAAGCTTTTTTAGATGAGGCAAAATTGTCTTATCATGATTTATTA
GGCAAAGAAGATGGTAGTGTAAAACAATCAAGTAAAACACGTCAAGAACG
CCTAAAGACTCAACAAAACTTTTATTTAAGGAAACATAAAGAATTACCTG
ATAAAGTGATGCTAGTTGATGATATCTATACAACGGGTATGACAATTCAA
TTGGCCAGTCAATTATTGCGTGAAAATGGTGTGAAAACAATAAAATCCTT
TTCTTTAGCAAGGTAA

Los Alamos National Laboratory • Est 1943

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