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Streptococcus mutans Search Results

Record: 1 of 1  
MiniMap IGR738 IGR739 IGR742 IGR737 IGR736 IGR743 IGR734 IGR740 IGR735 IGR744 SMu0843 patB, - SMu0853 cpsY, - SMu0844 mvaA, - SMu0855 SMu0848 SMu0847 SMu0849 atmA, - SMu0846 mvaD, - SMu0850 fni, - SMu0852 mvaK2, - SMu0851 SMu0845 SMu0843 patB, - SMu0853 cpsY, - SMu0844 mvaA, - SMu0855 SMu0848 SMu0847 SMu0849 atmA, - SMu0846 mvaD, - SMu0850 fni, - SMu0852 mvaK2, - SMu0851 SMu0845 patB, - SMu0853 cpsY, - SMu0844 mvaA, - SMu0855 SMu0854 SMu0854 SMu0843 SMu0848 SMu0847 SMu0849 atmA, - SMu0846 mvaD, - SMu0850 fni, - SMu0852 mvaK2, - SMu0851 SMu0845


LANL Gene ID: SMu0849

GenBank Locus Tag: SMU.936

DNA Molecule Name:
1  

GenBank ID:
24379380

Gene Name:


Definition:
amino acid ABC transporter, ATP-binding protein

Cellular Location:
Cytoplasm, Membrane [Evidence]

Gene Start:
887641

Gene Stop:
888405

Gene Length:
765

Molecular Weight*:
28343

pI*:
6.30

Net Charge*:
-2.59

EC:
 

Functional Class:
Transport and binding proteins; ABC Superfamily: ATP-binding protein  

Gene Ontology:
Molecular function
  GO:0000166    nucleotide binding
  GO:0005524    ATP binding
  GO:0016887    ATPase activity
  GO:0017111    nucleoside-triphosphatase activity


Pathway: pathway table

Comment:
For other components see SMu0848 (MSD1); SMu0847 (MSD2) and SMu0846 (SBP1).



View in HOMD Genome Viewer

Blast Summary:  PSI-Blast Search
Several matches in gapped BLAST to amino acid ABC transporter,
permease protein: residues 1-250 are 57% similar to the protein in
Listeria monocytogenes (16804384|).Residues 1-253 are 51% similar to the protein from S.pneumonia (15901310|).






The best hit to the Streptococcus agalactiae 2603 V/R genome is to SAG0718 (1e-64).


Top Blast Hits:  Updated monthly
Click here to view the entire PsiBlast results.
 gi|24379380|ref|NP_721335.1|  putative amino acid ABC transp...   498   e-139
 gi|125718884|ref|YP_001036017.1|  Amino acid ABC transporter...   411   e-113
 gi|126653496|ref|ZP_01725589.1|  putative amino acid ABC tra...   326   1e-87
 gi|146319721|ref|YP_001199433.1|  putative amino acid ABC tr...   317   5e-85
 gi|16804384|ref|NP_465869.1|  hypothetical protein lmo2346 [...   294   4e-78
 gi|16801502|ref|NP_471770.1|  hypothetical protein lin2440 [...   293   6e-78
 gi|46908516|ref|YP_014905.1|  amino acid ABC transporter, AT...   293   8e-78
 gi|153203876|ref|ZP_01944780.1|  amino acid ABC transporter,...   293   8e-78
 gi|126667887|ref|ZP_01738853.1|  Putative amino acid ABC tra...   286   6e-76
 gi|153852848|ref|ZP_01994285.1|  hypothetical protein DORLON...   285   2e-75


InterPro Summary:  InterProScan

InterPro
IPR003439
Domain
ABC transporter related
PD000006 [139-182]T 0.0 PD000006 ABC_transporter ABC_transporter
PF00005 [27-215]T 7.799983041256319E-60 PF00005 ABC_tran ABC_tran
PS00211 [140-154]T 8.0E-5 PS00211 ABC_TRANSPORTER_1 ABC_TRANSPORTER_1
PS50893 [2-239]T 0.0 PS50893 ABC_TRANSPORTER_2 ABC_TRANSPORTER_2
InterPro
IPR003593
Domain
AAA+ ATPase, core
SM00382 [26-216]T 3.79999999999991E-16 SM00382 AAA AAA
noIPR
unintegrated
unintegrated
G3DSA:3.40.50.300 [1-248]T 3.60002015030994E-78 G3DSA:3.40.50.300 G3DSA:3.40.50.300 G3DSA:3.40.50.300
PTHR19222 [2-246]T 0.0 PTHR19222 PTHR19222 PTHR19222
PTHR19222:SF33 [2-246]T 0.0 PTHR19222:SF33 PTHR19222:SF33 PTHR19222:SF33
SSF52540 [1-242]T 1.2999999999999998E-75 SSF52540 SSF52540 SSF52540


COGS Summary:  COGS Search
BeTs to 7 clades of COG1126
COG name: ABC-type polar amino acid transport system, ATPase component
Functional Class: E
The phylogenetic pattern of COG1126 is a-----vcEB-Huj----inx
Number of proteins in this genome belonging to this COG is 7
Blocks Summary:  Blocks Search
***** IPB001140 (ABC transporter transmembrane region) with a combined E-value of 5.5e-36.
    IPB001140A    16-62
    IPB001140B    137-175
    IPB001140C    191-220


 ProDom Summary:  Protein Domain Search
Residues 1-226 are 20% similar to a (C24F3.5) protein domain (PD218211 which is seen in Q21213_CAEEL.

Residues 183-223 are 65% similar to a (ATP-BINDING TRANSPORT COMPLETE PROTEOME ABC TRANSPORTER) protein domain (PD000079 which is seen in GLNQ_BACST.

Residues 2-226 are 23% similar to a (ATP-BINDING PROTEOME COMPLETE ABC) protein domain (PD313900 which is seen in Q9WZT4_THEMA.

Residues 184-225 are 61% similar to a (ATP-BINDING COMPLETE PROTEOME TRANSPORT) protein domain (PD007174 which is seen in HISP_SALTY.

Residues 130-226 are 27% similar to a (ABC TRANSPORTER) protein domain (PD058053 which is seen in O69995_STRCO.

Residues 22-229 are 24% similar to a (ATP-BINDING TRANSPORT COMPLETE MJ0121) protein domain (PD039360 which is seen in Y121_METJA.

Residues 123-215 are 31% similar to a (ATP-BINDING PROTEOME COMPLETE 230AA) protein domain (PD169303 which is seen in Q9WW89_LACLC.

Residues 138-182 are 51% similar to a (ATP-BINDING ABC TRANSPORTER PROTEOME) protein domain (PD334824 which is seen in YRBF_HAEIN.

Residues 1-52 are 51% similar to a (TRANSPORT ATP-BINDING IRON CHELATIN) protein domain (PD351726 which is seen in Y888_HELPY.

Residues 184-239 are 50% similar to a (ATP-BINDING TRANSPORT COMPLETE PROTEOME) protein domain (PD255463 which is seen in Q9ZK44_HELPJ.

Residues 140-219 are 35% similar to a (ATP-BINDING) protein domain (PD397028 which is seen in Q53712_STRAT.

Residues 184-223 are 67% similar to a (ATP-BINDING TRANSPORT PROTEOME COMPLETE) protein domain (PD359629 which is seen in Q9KGD1_BACHD.

Residues 97-236 are 23% similar to a (ABC-BINDING PROTEOME RELATED OLIGOPEPTIDE) protein domain (PD077779 which is seen in Q9HIQ1_THEAC.

Residues 17-64 are 54% similar to a (ATP-BINDING TRANSPORT ABC TRANSPORTER COMPLETE PROTEOME) protein domain (PD000005 which is seen in Q9PP29_CAMJE.

Residues 139-179 are 82% similar to a (ATP-BINDING TRANSPORT ABC TRANSPORTER COMPLETE PROTEOME) protein domain (PD000006 which is seen in YA78_HAEIN.


Paralogs:  Local Blast Search
SMu0849 is paralogously related (blast p-value < 1e-3) to SMu0418, SMu0517, SMu1380, SMu0731, SMu0218, SMu1079, SMu0971, SMu1762, SMu1210, SMu1920, SMu1288, SMu1003, SMu0786, SMu0235, SMu1246, SMu1231, SMu1068, SMu1950, SMu0884, SMu1518, SMu1751, SMu0916, SMu1036, SMu1037, SMu1949, SMu0594, SMu0944, SMu1023, SMu1428, SMu0596, SMu1001, SMu0335, SMu0805, SMu0234, SMu0216, SMu0164, SMu0390, SMu1517, SMu1410, SMu0907, SMu1757, SMu0976, SMu0374, SMu1064, SMu0258, SMu0476, SMu1710, SMu1093, SMu0950, SMu1065, SMu1649, SMu1316, SMu0836, SMu0825, SMu0824, SMu0823, SMu1959, SMu1724, SMu0837, SMu1545, SMu0986, SMu0475, SMu0224, SMu1306, SMu0987, SMu1050, SMu0024, SMu0752, SMu1811, SMu0666, SMu1202, SMu0729, and SMu1686 all with ATP-binding capabilities.


Pfam Summary:  Pfam Search
Residues 27 to 215 (E-value = 2e-61) place SMu0849 in the ABC_tran family which is described as ABC transporter (PF00005)

 Top PDB Hits:
pdb|1B0U|A Chain A, Atp-Binding Subunit Of The Histidine Permea... 225 4e-060
pdb|1G29|1 Chain 1, Malk >gi|12084695|pdb|1G29|2 Chain 2, Malk 124 1e-029

Gene Protein Sequence:
MLEIKNLSKQFGDKLVLDNVSLTVNKGDVVVILGPSGSGKTTFLRCLNHL
EKADKGHLTLDGQSYDLATLNRKEILTIRQKTAFVFQHYNLFANKTALEN
ILEGLMTARKIPKEQAIQIAEQALEKVGLLSYKDYYPSQLSGGQQQRIGI
ARAIAVKPDLIFFDEPTSALDPELIGDVLGVMKQLAEEGVTMIVVTHEMS
FAKDVANHVIFMDGGHIIEEASPKEFFSKPKEDRTRRFLARILSDDSYSV
DYIL

Gene Nucleotide Sequence:  Sequence Viewer
ATGTTAGAAATTAAAAATTTATCAAAACAATTTGGAGATAAACTTGTTCT
TGACAATGTTAGCTTGACTGTTAACAAGGGAGATGTTGTCGTTATTTTGG
GTCCTAGCGGTTCAGGAAAAACAACTTTTTTGCGCTGTCTTAATCATTTG
GAAAAAGCAGATAAAGGACATCTAACTTTAGATGGACAATCTTATGATTT
GGCAACACTTAATCGTAAAGAAATTTTGACCATTCGGCAAAAGACGGCCT
TTGTTTTTCAACACTATAATCTTTTTGCTAATAAAACCGCTTTGGAGAAT
ATTTTAGAAGGCTTAATGACTGCAAGAAAGATTCCCAAAGAACAAGCGAT
TCAAATTGCGGAGCAAGCCCTTGAAAAGGTAGGCTTATTGAGTTATAAAG
ATTATTATCCTAGTCAATTATCTGGTGGTCAGCAGCAAAGAATTGGGATT
GCACGTGCCATTGCAGTCAAGCCAGATCTTATCTTTTTTGATGAACCAAC
ATCGGCACTTGACCCTGAATTGATTGGTGATGTTTTGGGTGTCATGAAAC
AATTGGCTGAGGAAGGCGTTACCATGATTGTGGTCACGCATGAAATGAGT
TTTGCCAAAGATGTGGCCAATCATGTCATTTTTATGGATGGTGGGCACAT
CATCGAAGAAGCTTCGCCAAAAGAATTTTTCTCGAAACCTAAAGAAGACA
GGACGCGTCGCTTTTTAGCCCGGATTCTGTCTGATGATAGTTACTCAGTT
GATTATATATTGTAA

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