| | This journal provides immediate access to some articles. Special Report SNPs Meet CNVs in Genome-Wide Association Studies: HGV2007 Meeting Report Xavier Estivill, Nancy J. Cox, Stephen J. Chanock, Pui-Yan Kwok, Stephen W. Scherer, and Anthony J. Brookes PLoS Genet. 2008 April; 4(4): e1000068. Published online 2008 April 25. doi: 10.1371/journal.pgen.1000068.PMCID: PMC2330071 Review Defining the Role of the MHC in Autoimmunity: A Review and Pooled Analysis Michelle M. A. Fernando, Christine R. Stevens, Emily C. Walsh, Philip L. De Jager, Philippe Goyette, Robert M. Plenge, Timothy J. Vyse, and John D. Rioux PLoS Genet. 2008 April; 4(4): e1000024. Published online 2008 April 25. doi: 10.1371/journal.pgen.1000024.PMCID: PMC2291482 Research Articles A Genome-Wide Association Study of Psoriasis and Psoriatic Arthritis Identifies New Disease Loci Ying Liu, Cynthia Helms, Wilson Liao, Lisa C. Zaba, Shenghui Duan, Jennifer Gardner, Carol Wise, Andrew Miner, M. J. Malloy, Clive R. Pullinger, John P. Kane, Scott Saccone, Jane Worthington, Ian Bruce, Pui–Yan Kwok, Alan Menter, James Krueger, Anne Barton, Nancy L. Saccone, and Anne M. Bowcock PLoS Genet. 2008 April; 4(4): e1000041. Published online 2008 April 4. doi: 10.1371/journal.pgen.1000041.PMCID: PMC2274885 Genomic Islands in the Pathogenic Filamentous Fungus Aspergillus fumigatus Natalie D. Fedorova, Nora Khaldi, Vinita S. Joardar, Rama Maiti, Paolo Amedeo, Michael J. Anderson, Jonathan Crabtree, Joana C. Silva, Jonathan H. Badger, Ahmed Albarraq, Sam Angiuoli, Howard Bussey, Paul Bowyer, Peter J. Cotty, Paul S. Dyer, Amy Egan, Kevin Galens, Claire M. Fraser-Liggett, Brian J. Haas, Jason M. Inman, Richard Kent, Sebastien Lemieux, Iran Malavazi, Joshua Orvis, Terry Roemer, Catherine M. Ronning, Jaideep P. Sundaram, Granger Sutton, Geoff Turner, J. Craig Venter, Owen R. White, Brett R. Whitty, Phil Youngman, Kenneth H. Wolfe, Gustavo H. Goldman, Jennifer R. Wortman, Bo Jiang, David W. Denning, and William C. Nierman PLoS Genet. 2008 April; 4(4): e1000046. Published online 2008 April 11. doi: 10.1371/journal.pgen.1000046.PMCID: PMC2289846 An Increase in Mitochondrial DNA Promotes Nuclear DNA Replication in Yeast Heidi M. Blank, Chonghua Li, John E. Mueller, Lydia M. Bogomolnaya, Mary Bryk, and Michael Polymenis PLoS Genet. 2008 April; 4(4): e1000047. Published online 2008 April 25. doi: 10.1371/journal.pgen.1000047.PMCID: PMC2289842 Evolution and Control of Imprinted FWA Genes in the Genus Arabidopsis Ryo Fujimoto, Yuki Kinoshita, Akira Kawabe, Tetsu Kinoshita, Kazuya Takashima, Magnus Nordborg, Mikhail E. Nasrallah, Kentaro K. Shimizu, Hiroshi Kudoh, and Tetsuji Kakutani PLoS Genet. 2008 April; 4(4): e1000048. Published online 2008 April 4. doi: 10.1371/journal.pgen.1000048.PMCID: PMC2270340 Cell-to-Cell Stochastic Variation in Gene Expression Is a Complex Genetic Trait Juliet Ansel, Hélène Bottin, Camilo Rodriguez-Beltran, Christelle Damon, Muniyandi Nagarajan, Steffen Fehrmann, Jean François, and Gaël Yvert PLoS Genet. 2008 April; 4(4): e1000049. Published online 2008 April 11. doi: 10.1371/journal.pgen.1000049.PMCID: PMC2289839 Bmp4 Is Essential for the Formation of the Vestibular Apparatus that Detects Angular Head Movements Weise Chang, Zhengshi Lin, Holger Kulessa, Jean Hebert, Brigid L. M. Hogan, and Doris K. Wu PLoS Genet. 2008 April; 4(4): e1000050. Published online 2008 April 11. doi: 10.1371/journal.pgen.1000050.PMCID: PMC2274953 β-Globin LCR and Intron Elements Cooperate and Direct Spatial Reorganization for Gene Therapy Alla Buzina, Mandy Y. M. Lo, Angela Moffett, Akitsu Hotta, Eden Fussner, Rikki R. Bharadwaj, Peter Pasceri, J. Victor Garcia-Martinez, David P. Bazett-Jones, and James Ellis PLoS Genet. 2008 April; 4(4): e1000051. Published online 2008 April 18. doi: 10.1371/journal.pgen.1000051.PMCID: PMC2271131 A Genome-Wide Gene Expression Signature of Environmental Geography in Leukocytes of Moroccan Amazighs Youssef Idaghdour, John D. Storey, Sami J. Jadallah, and Greg Gibson PLoS Genet. 2008 April; 4(4): e1000052. Published online 2008 April 11. doi: 10.1371/journal.pgen.1000052.PMCID: PMC2290968 Global Transcriptome and Deletome Profiles of Yeast Exposed to Transition Metals Yong Hwan Jin, Paul E. Dunlap, Sandra J. McBride, Hanan Al-Refai, Pierre R. Bushel, and Jonathan H. Freedman PLoS Genet. 2008 April; 4(4): e1000053. Published online 2008 April 25. doi: 10.1371/journal.pgen.1000053.PMCID: PMC2278374 Heterogeneity of Breast Cancer Associations with Five Susceptibility Loci by Clinical and Pathological Characteristics Montserrat Garcia-Closas, Per Hall, Heli Nevanlinna, Karen Pooley, Jonathan Morrison, Douglas A. Richesson, Stig E. Bojesen, Børge G. Nordestgaard, Christen K. Axelsson, Jose I. Arias, Roger L. Milne, Gloria Ribas, Anna González-Neira, Javier Benítez, Pilar Zamora, Hiltrud Brauch, Christina Justenhoven, Ute Hamann, Yon-Dschun Ko, Thomas Bruening, Susanne Haas, Thilo Dörk, Peter Schürmann, Peter Hillemanns, Natalia Bogdanova, Michael Bremer, Johann Hinrich Karstens, Rainer Fagerholm, Kirsimari Aaltonen, Kristiina Aittomäki, Karl von Smitten, Carl Blomqvist, Arto Mannermaa, Matti Uusitupa, Matti Eskelinen, Maria Tengström, Veli-Matti Kosma, Vesa Kataja, Georgia Chenevix-Trench, Amanda B. Spurdle, Jonathan Beesley, Xiaoqing Chen, Australian Ovarian Cancer Management Group, The Kathleen Cuningham Foundation Consortium for Research into Familial Breast Cancer, Peter Devilee, Christi J. van Asperen, Catharina E. Jacobi, Rob A. E. M. Tollenaar, Petra E.A. Huijts, Jan G. M. Klijn, Jenny Chang-Claude, Silke Kropp, Tracy Slanger, Dieter Flesch-Janys, Elke Mutschelknauss, Ramona Salazar, Shan Wang-Gohrke, Fergus Couch, Ellen L. Goode, Janet E. Olson, Celine Vachon, Zachary S. Fredericksen, Graham G. Giles, Laura Baglietto, Gianluca Severi, John L. Hopper, Dallas R. English, Melissa C. Southey, Christopher A. Haiman, Brian E. Henderson, Laurence N. Kolonel, Loic Le Marchand, Daniel O. Stram, David J. Hunter, Susan E. Hankinson, David G. Cox, Rulla Tamimi, Peter Kraft, Mark E. Sherman, Stephen J. Chanock, Jolanta Lissowska, Louise A. Brinton, Beata Peplonska, Jan G. M. Klijn, Maartje J. Hooning, Han Meijers-Heijboer, J. Margriet Collee, Ans van den Ouweland, Andre G. Uitterlinden, Jianjun Liu, Low Yen Lin, Li Yuqing, Keith Humphreys, Kamila Czene, Angela Cox, Sabapathy P. Balasubramanian, Simon S. Cross, Malcolm W. R. Reed, Fiona Blows, Kristy Driver, Alison Dunning, Jonathan Tyrer, Bruce A. J. Ponder, Suleeporn Sangrajrang, Paul Brennan, James McKay, Fabrice Odefrey, Valerie Gabrieau, Alice Sigurdson, Michele Doody, Jeffrey P. Struewing, Bruce Alexander, Douglas F. Easton, and Paul D. Pharoah PLoS Genet. 2008 April; 4(4): e1000054. Published online 2008 April 25. doi: 10.1371/journal.pgen.1000054.PMCID: PMC2291027 Small RNA-Directed Epigenetic Natural Variation in Arabidopsis thaliana Jixian Zhai, Jun Liu, Bin Liu, Pingchuan Li, Blake C. Meyers, Xuemei Chen, and Xiaofeng Cao PLoS Genet. 2008 April; 4(4): e1000056. Published online 2008 April 25. doi: 10.1371/journal.pgen.1000056.PMCID: PMC2289841 Analysis of Chimpanzee History Based on Genome Sequence Alignments Jennifer L. Caswell, Swapan Mallick, Daniel J. Richter, Julie Neubauer, Christine Schirmer, Sante Gnerre, and David Reich PLoS Genet. 2008 April; 4(4): e1000057. Published online 2008 April 18. doi: 10.1371/journal.pgen.1000057.PMCID: PMC2278377 Identification of CIITA Regulated Genetic Module Dedicated for Antigen Presentation Michal Krawczyk, Queralt Seguín-Estévez, Elisa Leimgruber, Peter Sperisen, Christoph Schmid, Philipp Bucher, and Walter Reith PLoS Genet. 2008 April; 4(4): e1000058. Published online 2008 April 25. doi: 10.1371/journal.pgen.1000058.PMCID: PMC2278383 Coordinated Regulation of Intestinal Functions in C. elegans by LIN-35/Rb and SLR-2 Natalia V. Kirienko, John D. K. McEnerney, and David S. Fay PLoS Genet. 2008 April; 4(4): e1000059. Published online 2008 April 25. doi: 10.1371/journal.pgen.1000059.PMCID: PMC2312330 Proofreading Activity of DNA Polymerase Pol2 Mediates 3′-End Processing during Nonhomologous End Joining in Yeast Shun-Fu Tseng, Abram Gabriel, and Shu-Chun Teng PLoS Genet. 2008 April; 4(4): e1000060. Published online 2008 April 25. doi: 10.1371/journal.pgen.1000060.PMCID: PMC2312331 Primary Coenzyme Q Deficiency in Pdss2 Mutant Mice Causes Isolated Renal Disease Min Peng, Marni J. Falk, Volker H. Haase, Rhonda King, Erzsebet Polyak, Mary Selak, Marc Yudkoff, Wayne W. Hancock, Ray Meade, Ryoichi Saiki, Adam L. Lunceford, Catherine F. Clarke, and David L. Gasser PLoS Genet. 2008 April; 4(4): e1000061. Published online 2008 April 25. doi: 10.1371/journal.pgen.1000061.PMCID: PMC2291193 Correction Correction: Identification of Small Molecule Inhibitors of Pseudomonas aeruginosa Exoenzyme S Using a Yeast Phenotypic Screen Anthony Arnoldo, Jasna Curak, Saranya Kittanakom, Igor Chevelev, Vincent T. Lee, Mehdi Sahebol-Amri, Becky Koscik, Lana Ljuma, Peter J. Roy, Antonio Bedalov, Guri Giaever, Corey Nislow, A. Rod Merrill, Stephen Lory, and Igor Stagljar PLoS Genet. 2008 April; 4(4): 10.1371/annotation/76d35829-07a2-479f-bbc1-cce6755b6d8c. Published online 2008 April 2. doi: 10.1371/annotation/76d35829-07a2-479f-bbc1-cce6755b6d8c.PMCID: PMC2637088 Corrects: Anthony Arnoldo, et al. Identification of Small Molecule Inhibitors of Pseudomonas aeruginosa Exoenzyme S Using a Yeast Phenotypic Screen. PLoS Genet. 2008 February; 4(2): e1000005. |