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Streptococcus mutans Search Results

Record: 1 of 1  
MiniMap IGR1064 IGR1072 IGR1063 IGR1069 IGR1070 IGR1067 IGR1074 IGR1071 IGR1073 IGR1066 IGR1065 IGR1068 IGR1075 SMu1236 tpn, - SMu1238 tnp, - SMu1237 yjjB, - SMu1243 psaA, - SMu1231 ituA,mycA, - SMu1228 ylbB, - SMu1230 SMu1240 SMu1241 SMu1235 SMu1239 SMu1233 SMu1232 SMu1236 tpn, - SMu1238 tnp, - SMu1237 yjjB, - SMu1243 psaA, - SMu1231 ituA,mycA, - SMu1228 ylbB, - SMu1230 SMu1240 SMu1241 SMu1235 SMu1239 SMu1233 SMu1232 Type: tandem, Name: SMu-TR-22 - 22 Type: tandem, Name: SMu-TR-22 - 22 tpn, - SMu1238 tnp, - SMu1237 yjjB, - SMu1243 psaA, - SMu1231 ituA,mycA, - SMu1228 ylbB, - SMu1230 SMu1242 bacT,btsT, - SMu1229 bacT,btsT, - SMu1229 SMu1242 SMu1236 SMu1239 SMu1232 SMu1234 SMu1241 SMu1233 SMu1240 SMu1235 SMu1234


LANL Gene ID: SMu1231

GenBank Locus Tag: SMU.1348c

DNA Molecule Name:
1  

Genomic Island ID:
12

GenBank ID:
24379760

 Gene Name:
psaA  

 Definition:
ABC transporter, ATP-binding protein

 Cellular Location:
Cytoplasm, Membrane [Evidence]

 Gene Start:
1291333

Gene Stop:
1290632

Gene Length:
702

Molecular Weight*:
25868

pI*:
5.90

Net Charge*:
-2.31

EC:
 

 Functional Class:
Transport and binding proteins; ABC Superfamily: ATP-binding protein  

 Gene Ontology:
Molecular function
  GO:0000166    nucleotide binding
  GO:0005524    ATP binding
  GO:0016887    ATPase activity
  GO:0017111    nucleoside-triphosphatase activity


 Pathway: pathway table

 Comment:
For other components see SMu1230 (MSD1).

For other 'psa' genes see SMu1001 (psaA); SMu1067 (psaB);SMu1068 (psaA); SMu1069 (psaR); SMu1171 (psaR); SMu1752 (psaB) ; SMu1750 (psaR) and SMu1751 (psaA).



View in HOMD Genome Viewer

 Blast Summary:  PSI-Blast Search
This sequence corresponds to the previously published 15625442| , 4098078|, and 9802355|, predicted ABC transporters in GenBank. Significant hits in gapped BLAST to ABC transporter. Residues 2-233 are 59% similar to 15894109| as seen in Clostridium acetobutylicum. Residues 1-233 are 54% similar to 16800255| as seen in Listeria innocua.





The best hit to the Streptococcus agalactiae 2603 V/R genome is to SAG1004 (7e-73).


 Top Blast Hits:  Updated monthly
Click here to view the entire PsiBlast results.
 gi|24379760|ref|NP_721715.1|  putative ABC transporter, ATP-...   416   e-115
 gi|15894109|ref|NP_347458.1|  ABC transporter, ATP-binding p...   282   1e-74
 gi|154496083|ref|ZP_02034779.1|  hypothetical protein BACCAP...   280   7e-74
 gi|153812837|ref|ZP_01965505.1|  hypothetical protein RUMOBE...   278   2e-73
 gi|156866599|gb|EDO59971.1|  hypothetical protein CLOLEP_027...   278   2e-73
 gi|153855794|ref|ZP_01996795.1|  hypothetical protein DORLON...   275   1e-72
 gi|154503110|ref|ZP_02040170.1|  hypothetical protein RUMGNA...   274   2e-72
 gi|69244436|ref|ZP_00602852.1|  ABC transporter [Enterococcu...   273   5e-72
 gi|116493596|ref|YP_805330.1|  ABC-type antimicrobial peptid...   272   1e-71
 gi|153196000|ref|ZP_01940408.1|  ABC transporter, ATP-bindin...   271   3e-71


InterPro Summary:  InterProScan

InterPro
IPR003439
Domain
ABC transporter related
PD000006 [138-181]T 0.0 PD000006 ABC_transporter ABC_transporter
PF00005 [33-214]T 4.50001022902866E-52 PF00005 ABC_tran ABC_tran
PS00211 [139-153]T 8.0E-5 PS00211 ABC_TRANSPORTER_1 ABC_TRANSPORTER_1
PS50893 [4-231]T 0.0 PS50893 ABC_TRANSPORTER_2 ABC_TRANSPORTER_2
InterPro
IPR003593
Domain
AAA+ ATPase, core
SM00382 [32-215]T 3.5000000000002E-13 SM00382 AAA AAA
noIPR
unintegrated
unintegrated
G3DSA:3.40.50.300 [1-216]T 1.3000049540732398E-57 G3DSA:3.40.50.300 G3DSA:3.40.50.300 G3DSA:3.40.50.300
PTHR19222 [4-220]T 9.400030710307491E-90 PTHR19222 PTHR19222 PTHR19222
PTHR19222:SF32 [4-220]T 9.400030710307491E-90 PTHR19222:SF32 PTHR19222:SF32 PTHR19222:SF32
SSF52540 [1-216]T 4.5E-61 SSF52540 SSF52540 SSF52540


COGS Summary:  COGS Search
BeTs to 14 clades of COG1136
COG name: ABC-type (unclassified) transport system, ATPase component
Functional Class: R
The phylogenetic pattern of COG1136 is AMt--QVCEBRHUJGPOLinx
Number of proteins in this genome belonging to this COG is 8
Blocks Summary:  Blocks Search
***** IPB001140 (ABC transporter transmembrane region) with a combined E-value of 3.2e-41.
    IPB001140A    22-68
    IPB001140B    136-174
    IPB001140C    191-220


 ProDom Summary:  Protein Domain Search
Residues 123-198 are 36% similar to a (ATP-BINDING PROTEOME COMPLETE 230AA) protein domain (PD169303 which is seen in Q9WW89_LACLC.

Residues 75-112 are 63% similar to a (ATP-BINDING TRANSPORT ABC TRANSPORTER COMPLETE PROTEOME) protein domain (PD000230 which is seen in Q9CGJ3_LACLA.

Residues 23-216 are 24% similar to a (C24F3.5) protein domain (PD218211 which is seen in Q21213_CAEEL.

Residues 122-211 are 33% similar to a (ATP-BINDING TRANSPORTER ABC ABC-TYPE) protein domain (PD027424 which is seen in Q9CCF9_MYCLE.

Residues 17-219 are 26% similar to a (ATP-BINDING TRANSPORT COMPLETE MJ0121) protein domain (PD039360 which is seen in Y121_METJA.

Residues 26-73 are 58% similar to a (ATP-BINDING TRANSPORT ABC TRANSPORTER COMPLETE PROTEOME) protein domain (PD000005 which is seen in Q9CGJ3_LACLA.

Residues 138-181 are 79% similar to a (ATP-BINDING TRANSPORT ABC TRANSPORTER COMPLETE PROTEOME) protein domain (PD000006 which is seen in Q9CGJ3_LACLA.


Paralogs:  Local Blast Search
SMu1231 is paralogously related (blast p-value < 1e-3) to SMu1246, SMu1751, SMu1068, SMu0786, SMu1288, SMu0916, SMu1210, SMu1762, SMu1380, SMu1001, SMu1920, SMu0218, SMu0731, SMu0849, SMu0517, SMu0971, SMu1003, SMu0418, SMu0594, SMu1950, SMu1949, SMu1079, SMu0884, SMu0234, SMu0235, SMu1428, SMu0390, SMu0805, SMu1757, SMu0335, SMu1517, SMu0836, SMu1023, SMu0216, SMu0824, SMu1518, SMu0476, SMu1037, SMu0907, SMu0374, SMu0986, SMu1316, SMu1065, SMu0825, SMu1064, SMu1410, SMu0596, SMu0258, SMu1036, SMu0024, SMu1811, SMu0944, SMu1710, SMu1649, SMu0475, SMu0837, SMu0987, SMu0976, SMu1545, SMu1724, SMu0224, SMu1093, SMu0950, SMu0752, SMu0666, SMu1050, SMu0823, SMu0729, SMu0164, SMu1306, SMu1959, and SMu1686, all ATP-binding proteins.


Pfam Summary:  Pfam Search
Residues 33 to 214 (E-value = 9.9e-52) place SMu1231 in the ABC_tran family which is described as ABC transporter (PF00005)

 Top PDB Hits:
pdb|1B0U|A Chain A, Atp-Binding Subunit Of The Histidine Permea... 127 2e-030
pdb|1G29|1 Chain 1, Malk >gi|12084695|pdb|1G29|2 Chain 2, Malk 108 5e-025

Gene Protein Sequence:
MNIIEFKSVSKRYKVGNQEIEAVKHVSFNIESGEFVVVLGASGAGKSTIL
NLLGGMDTVSEGQILVEGQDIVNFSEKELTKYRAEKIGFVFQFYNLISNL
NTLENVEFAIEVSQKSLNPKDILKRVGLSERLKNFPSQLSGGEQQRVSIA
RAIAKNPLLLLCDEPTGALDYETGKEVLQLIKELNESTKKSVVLITHNSA
ISKIADKVIHVRSGQIEKIEYNSDKIPVSELEW

Gene Nucleotide Sequence:  Sequence Viewer
ATGAACATTATTGAATTTAAAAGTGTATCGAAAAGATACAAAGTAGGAAA
TCAGGAAATTGAAGCAGTAAAGCATGTTTCATTCAACATTGAATCCGGAG
AATTTGTAGTTGTTTTAGGAGCCAGTGGCGCTGGAAAAAGTACTATTCTT
AATTTATTGGGGGGAATGGATACAGTATCTGAAGGTCAAATACTTGTTGA
AGGACAGGATATTGTTAACTTCAGTGAAAAGGAATTAACAAAATACCGTG
CTGAAAAAATTGGTTTTGTTTTTCAATTTTATAACCTTATATCAAATTTG
AATACCCTAGAAAATGTGGAATTTGCCATAGAGGTATCCCAAAAATCTCT
GAATCCAAAGGATATTCTAAAAAGAGTAGGATTGTCTGAACGATTAAAGA
ACTTTCCTTCACAACTTTCAGGAGGTGAACAACAAAGGGTATCAATAGCA
CGAGCCATTGCTAAAAATCCTCTGTTATTACTCTGCGATGAACCTACAGG
AGCTTTAGATTATGAAACTGGGAAGGAAGTCCTTCAATTGATTAAGGAAT
TAAACGAAAGTACCAAAAAGAGCGTTGTTTTAATCACTCATAATAGTGCT
ATTTCAAAAATTGCCGATAAAGTCATTCATGTTCGAAGCGGACAAATCGA
GAAAATTGAATATAATTCAGATAAAATTCCAGTTTCAGAGTTAGAGTGGT
AA

Los Alamos National Laboratory • Est 1943

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