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Environmental Health Perspectives (EHP) is a monthly journal of peer-reviewed research and news on the impact of the environment on human health. EHP is published by the National Institute of Environmental Health Sciences and its content is free online. Print issues are available by paid subscription.DISCLAIMER
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Environmental Health Perspectives Volume 114, Number 3, March 2006 Open Access
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Epigenetics: The Science Of Change Epigenetics: The Science Of Change

Bob Weinhold

Abstract

The term “epigenetic” refers to any process that alters gene activity without changing the DNA sequence, and leads to modifications that can be transmitted to daughter cells. So far, the most compelling evidence linking epigenetic processes with disease has been found for cancer, but many other illnesses also have some level of evidence tying them to epigenetic mechanisms. Investment in epigenetics research has traditionally lagged behind that for traditional genetics research, but new initiatives, including large-scale research projects and a new professional society, are seeking to reverse this.

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