An Introduction to Genomics: The Human Genome and Beyond
<<Previous | 1 | 2 | 3 | 4 | Next>>
Genomics Applications
Fighting disease
Some human diseases and defects are directly or indirectly caused by genetic abnormalities. Sickle cell anemia, for example, is caused by a change in just one nucleotide out of six billion. Specific genes have been associated with breast cancer, deafness, and blindness. Some illnesses are caused by complex, interacting environmental and genetic factors and cannot be explained by classical inheritance patterns. Genome studies help medical researchers understand the molecular details of these diseases so they can pursue innovative drug treatments and more quickly identify high-risk individuals who could benefit from early medical intervention. And the analysis of the genomes of disease-causing microbes, viruses, and insects, such as the human malaria parasite and its carrier, the Anopheles mosquito, are helping in the development of new prevention and treatment strategies.
Protecting plant life
Fungi and other plant pathogens cause billions of dollars in damage every year to agricultural crops, plants, and trees. Sequencing their genomes is helping botanists and foresters find effective treatments. Better understanding of plant genetics is also improving crop yields and enhancing the nutritional value of food.
Harnessing nature's technology
Microbes--nature's simplest and most abundant organisms--can thrive under extreme conditions of heat, cold, pressure, and even radiation. By studying their genomes, scientists hope to find ways to use bacteria and other microorganisms to solve a variety of environmental problems, develop new energy sources, and improve industrial processes. Some microbes can help clean up hazardous waste sites by absorbing, transforming, or breaking down contaminants--a technique called bioremediation. Others can help combat global warming by absorbing, or sequestering, carbon from the atmosphere. And microbes can convert a wide range of organic and inorganic materials into renewable energy.
<<Previous | 1 | 2 | 3 | 4 | Next>>