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| Second International Meeting on Molecular Mechanisms of Metal Toxicity and Carcinogenicity Minerals Purchase This Issue | |
Oxidative and Free Radical Effects
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- Chemical Models Important in Understanding the Ways in which Chromate Can Damage DNA
- Paul O'Brien and Andreas Kortenkamp
p. 3
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- Oxidizing Intermediates Generated in the Fenton Reagent: Kinetic Arguments Against the Intermediacy of the
Hydroxyl Radical
- David A. Wink, Christian B. Wink, Raymond W. Nims, and Peter C. Ford
p. 11
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- Active Oxygen Species in DNA Damage Induced by Carcinogenic Metal Compounds
- Shosuke Kawanishi, Sumiko Inoue, and Koji Yamamoto
p. 17
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- Chromium(VI) Reduction by Ascorbate: Role of Reactive Intermediates in DNA Damage In Vitro
- Diane M. Stearns, Kevin D. Courtney, Paloma H. Giangrande, Laura S. Phieffer, and Karen E. Wetterhahn
p. 21
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- Evidence for Radical Species as Intermediates in Cadmium/Zinc-Metallothionein-dependent DNA Damage In Vitro
- Thomas Müller, Rainer Schuckelt, and Lothar Jaenicke
p. 27
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- Role of Paramagnetic Chromium in Chromium(VI)-induced Damage in Cultured Mammalian Cells
- Masayasu Sugiyama
p. 31
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- Vanadium Distribution in Rats and DNA Cleavage by Vanadyl Complex: Implication for Vanadium Toxicity and Biological Effects
- Hiromu Sakurai
p. 35
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Genotoxicity
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- Induction of Lung-specific DNA Damage by Metabolically Methylated Arsenics via the Production of Free Radicals
- Kenzo Yamanaka and Shoji Okada
p. 37
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- Effects of Chromium on DNA Replication In Vitro
- Elizabeth T. Snow
p. 41
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- Role of DNA Repair Inhibition in Lead- and Cadmium-induced Genotoxicity: A Review
- Andrea Hartwig
p. 45
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- Effects of Metal Treatment on DNA Repair in Polyamine-depleted HeLa Cells with Special Reference to Nickel
- Ronald D. Snyder
p. 51
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- Mutagenesis by Metal-induced Oxygen Radicals
- Thomas M. Reid, Daniel I. Feig, and Lawrence A. Loeb
p. 57
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- Metal Mutagenesis in Transgenic Chinese Hamster Cell Lines
- Catherine B. Klein, Biserka Kargacin, Lin Su, Sofia Cosentino, Elizabeth T. Snow, and Max Costa
p. 63
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- Toxicity, Uptake, and Mutagenicity of Particulate and Soluble Nickel Compounds
- Glenn G. Fletcher, Franco E. Rossetto, John D. Turnbull, and Evert Nieboer
p. 69
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- The Role of Mutagenic Metal Ions in Mediating In Vitro Mispairing by Alkylpyrimidines
- Opinder S. Bhanot and Jerome J. Solomon
p. 81
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- Enhanced Generation of Hydroxyl Radical and Sulfur Trioxide Anion Radical from Oxidation of Sodium Sulfite, Nickel(II) Sulfite, and Nickel Subsulfide in the Presence of Nickel(II) Complexes
- Xianglin Shi, Naresh Dalal, and Kazimierz Stanislaw Kasprzak
p. 91
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Resistance Mechanisms
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- Induction of Arsenite Tolerance and Thermotolerance by Arsenite Occur by Different Mechanisms
- Zaolin Wang , Guoying Hou and Toby G. Rossman
p. 97
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- Differential Cytotoxic Effects of Arsenic on Human and Animal Cells
- Te-Chang Lee and I-Ching Ho
p. 101
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- Newer Systems for Bacterial Resistances to Toxic Heavy Metals
- Simon Silver and Guangyong Ji
p. 107
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Carcinogenesis
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- Role of Lead-binding Proteins in Renal Cancer
- Bruce A. Fowler, Mary W. Kahng, and Donald R. Smith
p. 115
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- Nickel-Induced Alterations in Human Renal Epithelial Cells
- Aage Haugen, Lovise Maehle, Steen Mollerup, Edgar Rivedal, and David Ryberg
p. 117
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- Molecular Mechanisms of Transformation of C3H/lOTl/2 Cl 8 Mouse Embryo Cells and Diploid Human Fibroblasts by Carcinogenic Metal Compounds.
- Joseph R. Landolph
p. 119
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- Molecular Mechanisms of Nickel Carcinogenesis
- Max Costa, Konstantin Salnikow, Sofia Cosentino, Catherine B. Klein, Xi Huang, and Zhixiong Zhuang
p. 127
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Carcinogenesis and Metallothionein
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- The Significance of the Nuclear and Cytoplasmic Localization of Metallothionein in Human Liver and Tumor Cells
- M. George Cherian
p. 131
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- Apparent Quiescence of the Metallothionein Gene in the Rat Ventral Prostate: Association with Cadmium-Induced Prostate Tumors in Rats
- Timothy P. Coogan, Noriyuki Shiraishi, and Michael P. Waalkes
p. 137
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- In Vitro and In Vivo Studies on the Degradation of Metallothionein
- Curtis D. Klaassen, Supratim Choudhuri, James M. McKim, Jr., Lois D. Lehman-McKeeman, and William C. Kershaw
p. 141
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Toxicity: Molecular and Cellular Mechanisms
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- Monitoring Metal Concentrations in Tissues and Single Cells Using Ultramicrosensors
- Tadeusz Malinski, Saul Grunfeld, Ziad Taha, and Paul Tomboulian
p. 147
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- Metal Interactions with Voltage- and Receptor- Activated Ion Channels
- Henk P.M. Vijverberg, Marga Oortgiesen, Trese Leinders, and Regina G.D.M. van Kleef
p. 153
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- Induction of Internucleosomal DNA Fragmentation by Carcinogenic Chromate: Relationship to DNA Damage, Genotoxicity, and Inhibition of Macromolecular Synthesis
- Francis C.R. Manning, Lori J. Blankenship, John P. Wise, Jian Xu, Laura C. Bridgewater, and Steven R. Patierno
p. 159
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- In Vivo Effects of Chromium
- Charlotte Witmer, Ellen Faria, Hyoung-Sook Park, Nakissa Sadrieh, Edward Yurkow, Sean O'Connell, Andrea Sirak, and Heinz Schleyer
p. 169
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- Effects of Cadmium on Nuclear Protein Kinase
- Detmar Beyersmann, Christoph Block, and Anant N. Malviya
p. 177
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- Transmembrane Signals and Protooncogene Induction Evoked by Carcinogenic Metals and Prevented by Zinc
- Jeffrey Bingham Smith, Lucinda Smith, Vivian Pijuan, Yingxin Zhuang, and Yueh-Chu Chen
p. 181
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- Subcellular Targets of Cadmium Nephrotoxicity: Cadmium Binding to Renal Membrane Proteins in Animals With or Without Protective Metallothionein Synthesis
- Gunnar F. Nordberg, Taiyi Jin, and Monica Nordberg
p. 191
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- Metal Replacement in "Zinc Finger" and its Effect on DNA Binding
- Paul F. Predki and Bibudhendra Sarkar
p. 195
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Toxicity: Organs and Organisms
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- Experimental Localization of Intestinal Uptake Sites for Metals (Cd, Hg, Zn, Se) In Vivo in Mice
- Ole Andersen, Jesper Bo Nielsen, Jens Ahm Sorensen, and Leif Scherrebeck
p. 199
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- Iron and Aluminum Homeostasis in Neural Disorders
- Jayant G. Joshi, Madhu Dhar, Martin Clauberg, and Vijay Chauthaiwale
p. 207
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- Influence of the Common Human delta-Aminolevulinate Dehydratase Polymorphism on Lead Body Burden
- James G. Wetmur
p. 215
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- Occupational Exposures to Cd, Ni, and Cr Modulate Titers of Antioxidized DNA Base Autoantibodies
- Krystyna Frenkel, Jerzy Karkoszka, Beverly Cohen, Boguslaw Bara´nski, Marek Jakubowski, Greg Cosma, Emanuela Taioli, and Paolo Toniolo
p. 221
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Chromium Toxicology and Carcinogenesis
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- Use of Denaturing-gradient Gel Electrophoresis to Study Chromium-induced Point Mutations in Human Cells
- Jia Chen and William G. Thilly
p. 227
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- Generation of Hydroxyl Radical by Chromate in Biologically Relevant Systems: Role of Cr(V) Complexes versus Tetraperoxochromate(V)
- Xianglin Shi and N.S. Dalal
p. 231
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- The Generation of DNA Single-Strand Breaks During the Reduction of Chromate by Ascorbic Acid and/or Glutathione In Vitro
- Andreas Kortenkamp and Paul O'Brien
p. 237
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- Reactive Oxygen Species Produced from Chromate Pigments and Ascorbate
- Yves Lefebvre and Henri Pezerat
p. 243
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- Protective Effects of Thiol Compounds on Chromate-induced Toxicity In Vitro and In Vivo.
- Nobuyuki Susa, Shunji Ueno, and Yoshinori Furukawa
p. 247
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- Complexing of Amino Acids to DNA by Chromate in Intact Cells
- Victoria Voitkun, Anatoly Zhitkovich, and Max Costa
p. 251
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Cadmium Toxicology and Carcinogenesis
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- Correlation between Cadmium-induced Pulmonary Carcinogenicity, Metallothionein Expression, and Inflammatory Processes: A Species Comparison
- G. Oberdörster, M. G. Cherian, and R. B. Baggs
p. 257
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- Interference of Cadmium with ATP-stimulated Nuclear Calcium Uptake
- Stefan Hechtenberg and Detmar Beyersmann
p. 265
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- Effects of Zinc and Cadmium on Apoptotic DNA Fragmentation in Isolated Bovine Liver Nuclei
- Ruth D. Lohmann and Detmar Beyersmann
p. 269
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- Effect of Cadmium on Liver Regeneration after Partial Hepatectomy in Rats
- Alexandra Margeli, Stamatios Theocharis , Spyridon Skaltsas, Antigone Skopelitou, and Michael Mykoniatis
p. 273
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- Effect of Progesterone Pretreatment on Cadmium Toxicity in Male Fischer (F344/NCr) and Wistar (WF/NCr) Rats
- Noriyuki Shiraishi, Robert A. Barter, Hiroshi Uno, and Michael P. Waalkes
p. 277
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Nickel and Arsenic Toxicology/Carcinogeneis
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- The Role of Nickel and Nickel-mediated Reactive Oxygen Species in the Mechanism of Nickel Carcinogenesis
- Xi Huang, Zhixiong Zhuang, Krystyna Frenkel, Catherine B. Klein, and Max Costa
p. 281
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- DNA Damage Induced in Cultured Human Alveolar (L-132) Cells by Exposure to Dimethylarsinic Acid
- Koichi Kato, Hirotaka Hayashi, Akira Hasegawa, Kenzo Yamanaka, and Shoji Okada
p. 285
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- Transformation of Human Osteoblasts to Anchorage-Independent Growth by Insoluble Nickel Particles
- Xinhua Lin and Max Costa
p. 289
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- Glutathione Transferases in the Urine: Sensitive Methods for Detection of Kidney Damage Induced by Nephrotoxic Agents in Humans
- Anders Sundberg, Eeva-Liisa Appelkvist, Gustav Dallner, and Robert Nilsson
p. 293
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- Antagonistic Effect of Nickel on the Fermentative Growth of Escherichia coli K-12 and Comparison of Nickel and Cobalt Toxicity on the Aerobic and Anaerobic Growth
- Long-Fei Wu, Clarisse Navarro, Karinne de Pina, Martine Quénard, and Marie-Andrée Mandrand
p. 297
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- Development of an 125I-Postlabeling Assay as a Simple, Rapid, and Sensitive Index of DNA-protein Cross-links
- Zhixiong Zhuang and Max Costa
p. 301
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Mercury Toxicology
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- Inorganic Mercury Exposure, Mercury-Copper Interaction, and Dmps Treatment in Rats
- Maja Blanusa, Ljerka Prester, Snjezana Radi´c, and Biserka Kargacin
p. 305
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- Monoisoamyl meso-2,3-Dimercaptosuccinate as a Delayed Treatment for Mercury Removal in Rats
- Krista Kostial, Biserka Kargacin, Maja Blanusa, Martina Piasek, Mark M. Jones, and Pramod K. Singh
p. 309
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- Establishment and Characterization of a Methylmercury-resistant PC12 Cell Line
- Kyoko Miura, Thomas W. Clarkson, Kazumasa Ikeda, Akira Naganuma, and Nobumasa Imura
p. 313
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- Dose and Time Relations in Hg++-Induced Tubular Necrosis and Regeneration
- Jesper Bo Nielsen, Helle Raun Andersen, Ole Andersen and Henrik Starklint
p. 317
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Other Topics
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- Effects of Simultaneous Low-level Dietary Supplementation with Inorganic and Organic Selenium on Whole-Body, Blood, and Organ Levels of Toxic Metals in Mice
- Ole Andersen and Jesper Bo Nielsen
p. 321
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- Effects of Organometals on Cellular Signaling. I. Influence of Metabolic Inhibitors on Metal-induced Arachidonic Acid Liberation
- Andrea Käfer and Harald F. Krug
p. 325
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- Effects of Organometals on Cellular Signalling. II. Inhibition of Reincorporation of Free Arachidonic Acid and Influence on paf-acether Synthesis by Triethyllead
- Harald F. Krug, Dorit Mattern, Jocelyne Bidault, and Ewa Ninio
p. 331
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- Bioavailability of Biologically Detoxified Lead: Risks Arising from Consumption of Polluted Mussels
- Francesco Regoli and Enzo Orlando
p. 335
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- Respiratory Toxicity of Copper
- A. Romeu-Moreno, C. Aguilar, Ll. Arola, and A. Mas
p. 339
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- DNA Single-Strand Breaks and Cytotoxicity Induced by Chromate(VI), Cadmium(II), and Mercury(II) in Hydrogen Peroxide-resistant Cell Lines
- Katsuyuki Tsuzuki, Masayasu Sugiyama, and Nobuya Haramaki
p. 341
Last update: January 10, 1999 |
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