Philip M. Iannaccone MD, PhD

Philip M. Iannaccone, MD, PhD, is the George M. Eisenberg Professor in the Department of Pediatrics at the Children's Memorial Research Center, Feinberg School of Medicine, Northwestern University. He is the deputy director for basic research at the Children's Memorial Research Center (CMRC) and the director of the Developmental Biology Program at CMRC, which houses his active research lab. Dr. Iannaccone received his baccalaureate degrees from the State University of New York College of Environmental Sciences and Forestry and Syracuse University. He received his MD from the State University of New York Upstate Medical Center and completed his residency training in pathology at Columbia University College of Physicians and Surgeons in New York City. He received his PhD (DPhil) from Lincoln College, University of Oxford, England. His thesis research established the clonal origin of chemically induced tumors, a conclusion that he extended to preneoplastic lesions.

Dr. Iannaccone has published more than 100 peer-reviewed publications, editorials, book chapters, and books in a wide range of scientific journals. He has been engaged in environmental sciences at the national level for many years, serving as the chairman of the Board of Scientific Counselors at the National Institute of Environmental Health Sciences, as a member of the National Advisory Environmental Health Sciences Council, and as a member of numerous NIH advisory panels for priorities, strategy, and policy planning.

Dr. Iannaccone's current research is on the Sonic hedgehog/GLI signal transduction pathway in normal development and disease. His lab also studies the distribution of stem cell progeny in organ development using genetic chimeras. Most recently his lab has demonstrated the tumor suppressor Quaking inhibits translation of the oncogene GLI1 through binding of the 3'UTR.