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Environmental Health Perspectives (EHP) is a monthly journal of peer-reviewed research and news on the impact of the environment on human health. EHP is published by the National Institute of Environmental Health Sciences and its content is free online. Print issues are available by paid subscription.DISCLAIMER
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Environmental Health Perspectives Volume 113, Number 10, October 2005 Open Access
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Are EDCs Blurring Issues of Gender? Are EDCs Blurring Issues of Gender?

Ernie Hood

Abstract

Endocrine-disrupting chemicals (EDCs) lie at the heart of one of toxicology’s most widely argued controversies. Most of the controversy swirls around the potential effects of low-dose environmentally relevant exposures, especially fetal and early childhood exposures, which some scientists believe could have profound, permanent impacts on subsequent development and adult outcomes. Critics of this idea maintain that thus far there is no credible evidence to suggest that low-dose exposures cause any adverse human health effects. Yet a growing body of evidence offers some indication that prenatal and childhood exposure to EDCs may contribute to a variety of abnormalities in human sexuality, gender development and behaviors, reproductive capabilities, and sex ratios.

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