| Lead Poisoning--One Approach to a Problem That Won't Go Away John D. Bogden,
1
James M. Oleske,
2
Donald B. Louria
1
1
Department of Preventive Medicine and Community Health; and
2
Department of Pediatrics, UMDNJ-New Jersey Medical School, Newark, NJ 07103-2714 USA Abstract
A reduction in sources of environmental lead exposure has resulted in substantial declines in mean blood lead concentrations of all age groups in the United States. However, some segments of the population continue to have unacceptable levels of lead exposure and elevated blood lead concentrations. In addition, virtually all residents of industrialized countries have bone lead stores that are several orders of magnitude greater than those of our preindustrial ancestors. Recent studies suggest that these skeletal lead stores adversely affect health and can contribute to reduced birth weights, aggressive behavior in children, and anemia, hypertension, and kidney disease in adults. Evidence is described that demonstrates that an increase in dietary calcium consumption can reduce lead absorption and toxicity from exogenous and endogenous lead exposure. A relatively inexpensive and effective way to reduce the substantial morbidity that will result from widespread lead exposure is by fortification of a variety of foods with low levels of calcium. This approach can complement other efforts to prevent lead exposure and reduce lead toxicity. Key words : bone, calcium, food, lead, toxicity. Environ Health Perspect 105:1284-1287 (1997) .
Address correspondence to J.D. Bogden, Department of Preventive Medicine and Community Health, UMDNJ-New Jersey Medical School, 185 South Orange Avenue, Newark, NJ 07103-2714 USA. This work was supported by grants from the Foundation of the University of Medicine and Dentistry of New Jersey and grant HL56581 from the National Institutes of Health. Received 15 July 1997 ; accepted 14 August 1997.
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