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Environmental Health Perspectives (EHP) is a monthly journal of peer-reviewed research and news on the impact of the environment on human health. EHP is published by the National Institute of Environmental Health Sciences and its content is free online. Print issues are available by paid subscription.DISCLAIMER
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Environmental Health Perspectives Volume 98, 1992
Environmental Health Perspectives  1992 Biomarkers in Human Cancer-Part I, : Predisposition and Use in Risk Assessment

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Multiple genetic alterations in human carcinogenesis
Sugimura-T; Terada-M; Yokota-J; Hirohashi-S; Wakabayashi-K
p. 5
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Role of proto-oncogene activation in carcinogenesis
Anderson-MW; Reynolds-SH; You-M; Maronpot-RM
p. 13
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Tumor-suppressor genes: cardinal factors in inherited predisposition to human cancers
Evans-HJ; Prosser-J
p. 25
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Perinatal and multigenerational effect of carcinogens: possible contribution to determination of cancer susceptibility
Yamasaki-H; Loktionov A; Tomatis-L
p. 39
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Intragenomic repair heterogeneity of DNA damage
Scicchitano-DA; Hanawalt-PC
p. 45
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Cisplatin-DNA damage and repair in peripheral blood leukocytes in vivo and in vitro
Dabholkar-M; Bradshaw-L; Parker-RJ; Gill-I; Bostick-Bruton-F; Muggia-FM; Reed-E
p. 53
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Relationship of H-ras-1, L-myc, and p53 polymorphisms with lung cancer risk and prognosis
Weston A; Caporaso-NE; Perrin-LS; Sugimura-H; Tamai-S; Krontiris-TG; Trump-BF; Hoover-RN; Harris-CC
p. 61
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Polymorphisms for aromatic amine metabolism in humans: relevance for human carcinogenesis
Kadlubar-FF; Butler-MA; Kaderlik-KR; Chou-HC; Lang-NP
p. 69
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Elucidation of catalytic specificities of human cytochrome P450 and glutathione S-transferase enzymes and relevance to molecular epidemiology
Guengerich-FP; Shimada-T; Raney-KD; Yun-CH; Meyer-DJ; Ketterer-B; Harris-TM; Groopman-JD; Kadlubar-FF
p. 75
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Human cytochromes P450: evolution and cDNA-directed expression
Gonzalez-FJ; Gelboin-HV
p. 81
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The human glutathione S-transferase supergene family, its polymorphism, and its effects on susceptibility to lung cancer
Ketterer-B; Harris-JM; Talaska-G; Meyer-DJ; Pemble-SE; Taylor-JB; Lang-NP; Kadlubar-FF
p. 87
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Interindividual variation in carcinogen metabolism and bladder cancer risk
Vineis-P; Ronco-G
p. 95
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The debrisoquine metabolic phenotype and DNA-based assays: implications of misclassification for the association of lung cancer and the debrisoquine metabolic phenotype
Caporaso-NE; Shields-PG; Landi-MT; Shaw-GL; Tucker-MA; Hoover-R; Sugimura-H; Weston A; Harris-CC
p. 101
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Molecular genetic analysis of the cytochrome P450-debrisoquine hydroxylase locus and association with cancer susceptibility
Smith-CA; Moss-JE; Gough AC; Spurr-NK; Wolf-CR
p. 107
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Genetic monitoring of human polymorphic cancer susceptibility genes by polymerase chain reaction: application to glutathione transferase mu
Bell-DA; Thompson-CL; Taylor-J; Miller-CR; Perera-F; Hsieh-LL; Lucier-GW
p. 113
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Carcinogen metabolism in human lung tissues and the effect of tobacco smoking: results from a case--control multicenter study on lung cancer patients
Bartsch-H; Petruzzelli-S; De-Flora-S; Hietanen-E; Camus AM; Castegnaro-M; Alexandrov-K; Rojas-M; Saracci-R; Giuntini-C
p. 119
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Integrated approach for evaluating species and interindividual differences in responsiveness to dioxins and structural analogs
Clark-G; Tritscher A; Bell-D; Lucier-G
p. 125
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DNA adducts and related biomarkers in populations exposed to environmental carcinogens
Perera-F; Brenner-D; Jeffrey A; Mayer-J; Tang-D; Warburton-D; Young-TI; Wazneh-L; Latriano-L; Motykiewicz-G; et-al
p. 133
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Application of biomarkers to risk assessment
Gaylor-DW; Kadlubar-FF; Beland-FA
p. 139
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Biomarkers in epidemiology: scientific issues and ethical implications
Schulte-PA
p. 143
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Biomarkers in occupational cancer epidemiology: considerations in study design
Hayes-RB
p. 149
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Contributions from molecular/biochemical approaches in epidemiology to cancer risk assessment and prevention
Lohman-PH; Morolli-B; Darroudi-F; Natarajan AT; Gossen-JA; Venema-J; Mullenders-LH; Vogel-EW; Vrieling-H; van-Zeeland AA
p. 155
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Molecular epidemiology in cancer risk assessment and prevention: recent progress and avenues for future research
Wogan-GN
p. 167
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Immunohistochemical detection of pulmonary cytochrome P450IA and metabolic activities associated with P450IA1 and P450IA2 isozymes in lung cancer patients
Anttila-S; Vainio-H; Hietanen-E; Camus AM; Malaveille-C; Brun-G; Husgafvel-Pursiainen-K; Heikkila-L; Karjalainen A; Bartsch-H
p. 179
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Detection of ras gene mutations in human lung cancer: comparison of two screening assays based on the polymerase chain reaction
Husgafvel-Pursiainen-K; Ridanpaa-M; Hackman-P; Anttila-S; Karjalainen A; Onfelt A; Borresen AL; Vainio-H
p. 183
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Allele diversity of the H-ras-1 variable number of tandem repeats in Norwegian lung cancer patients
Ryberg-D; Tefre-T; Skaug-V; Stangeland-L; Ovrebo-S; Naalsund A; Borresen AL; Haugen A
p. 187
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Polycyclic aromatic hydrocarbon-DNA adducts and the CYP1A1 restriction fragment length polymorphism
Shields-PG; Sugimura-H; Caporaso-NE; Petruzzelli-SF; Bowman-ED; Trump-BF; Weston A; Harris-CC
p. 191
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Aberrant crypt foci and microadenoma as markers for colon cancer
Archer-MC; Bruce-WR; Chan-CC; Corpet-DE; Medline A; Roncucci-L; Stamp-D; Zhang-XM
p. 195
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Use of breath hydrogen and methane as markers of colonic fermentation in epidemiologic studies: circadian patterns of excretion
Le-Marchand-L; Wilkens-LR; Harwood-P; Cooney-RV
p. 199
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Role of lime in the generation of reactive oxygen species from betel-quid ingredients
Nair-UJ; Obe-G; Friesen-M; Goldberg-MT; Bartsch-H
p. 203
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Cross-sectional study with multiple measurements of biological markers for assessing stomach cancer risks at the population level
Tsugane-S; Tsuda-M; Gey-F; Watanabe-S
p. 207
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Biomarkers for individual susceptibility to carcinogenic agents: excretion and carcinogenic risk of benzo[a]pyrene metabolites
Likhachev AJ; Beniashvili-DSh; Bykov-VJ; Dikun-PP; Tyndyk-ML; Savochkina-IV; Yermilov-VB; Zabezhinski-MA
p. 211
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Determination of point mutational spectra of benzo[a]pyrene-diol epoxide in human cells
Keohavong-P; Thilly-WG
p. 215
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Nongenotoxic carcinogens: an extension of the perspective provided by Perera [comment]
Ashby-J; Purchase-IF
p. 223
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Development of source testing, analytical, and mutagenicity bioassay procedures for evaluating emissions from municipal and hospital waste combustors
Watts-RR; Lemieux-PM; Grote-RA; Lowans-RW; Williams-RW; Brooks-LR; Warren-SH; DeMarini-DM; Bell-DA; Lewtas-J
p. 227
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EPA priorities for biologic markers research in environmental health
Fowle-JR 3d; Sexton-K
p. 235
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The findings of the Agency for Toxic Substances and Disease Registry Medical Waste Tracking Act report
Lichtveld-MY; Rodenbeck-SE; Lybarger-JA
p. 243
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Determinants of serum zinc in a random population sample of four Belgian towns with different degrees of environmental exposure to cadmium
Thijs-L; Staessen-J; Amery A; Bruaux-P; Buchet-JP; Claeys-F; De-Plaen-P; Ducoffre-G; Lauwerys-R; Lijnen-P; et-al
p. 251
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Toxicity of vesicant agents scheduled for destruction by the Chemical Stockpile Disposal Program
Watson AP; Griffin-GD
p. 259
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The third United States-Japan meeting on the Toxicological Characterization of Environmental Chemicals
Kurokawa-Y; Damstra-T
p. 281
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