DNA adducts as a dosimeter for risk estimation
Belinsky-SA; White-CM; Devereux-TR; Anderson-MW
p. 3
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Preferential DNA repair in expressed genes
Hanawalt-PC
p. 9
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Activation of dihaloalkanes by glutathione conjugation and formation of DNA adducts
Guengerich-FP; Peterson-LA; Cmarik-JL; Koga-N; Inskeep-PB
p. 15
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Inflammation, oxidative DNA damage, and carcinogenesis
Lewis-JG; Adams-DO
p. 19
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Nearest neighbor affects G: C to A: T transitions induced by alkylating agents
Glickman-BW; Horsfall-MJ; Gordon AJ; Burns-PA
p. 29
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Mutations and homologous recombination induced in mammalian cells by metabolites of benzo[a]pyrene and 1-nitropyrene
Maher-VM; Patton-JD; Yang-JL; Wang-YY; Yang-LL; Aust AE; Bhattacharyya-N; McCormick-JJ
p. 33
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32P-postlabeling assay for carcinogen-DNA adducts: nuclease P1-mediated enhancement of its sensitivity and applications
Reddy-MV; Randerath-K
p. 41
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An approach to the determination of the relative potencies of chemical agents during the stages of initiation and promotion in multistage hepatocarcinogenesis in the rat
Pitot-HC; Campbell-HA
p. 49
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High- to low-dose extrapolation: critical determinants involved in the dose response of carcinogenic substances
Swenberg-JA; Richardson-FC; Boucheron-JA; Deal-FH; Belinsky-SA; Charbonneau-M; Short-BG
p. 57
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Cellular and molecular mechanisms of multistep carcinogenesis: relevance to carcinogen risk assessment
Barrett-JC; Wiseman-RW
p. 65
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Ah receptor: relevance of mechanistic studies to human risk assessment
Cook-JC; Gaido-KW; Greenlee-WF
p. 71
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Placental markers of human exposure to polychlorinated biphenyls and polychlorinated dibenzofurans
Lucier-GW; Nelson-KG; Everson-RB; Wong-TK; Philpot-RM; Tiernan-T; Taylor-M; Sunahara-GI
p. 79
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Role of protein kinase C in regulation of gene expression and relevance to tumor promotion
Johnson-MD; Housey-GM; O'Brian-CA; Kirschmeier-PT; Weinstein-IB
p. 89
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Implications of pharmacokinetic modeling in risk assessment analysis
Lutz-RJ; Dedrick-RL
p. 97
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Pharmacokinetics and expert systems as aids for risk assessment in reproductive toxicology
Mattison-DR; Jelovsek-FR
p. 107
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Cancer risk models for ionizing radiation
Hoel-DG
p. 121
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Statistical properties of a two-stage model of carcinogenesis
Portier-CJ
p. 125
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Effects of time-variant exposure on toxic substance response
Morrison-PF
p. 133
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The potential usefulness of biological markers in risk assessment
Perera-F
p. 141
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Human hypervariable sequences in risk assessment: rare Ha-ras alleles in cancer patients
Krontiris-TG; DiMartino-NA; Mitcheson-HD; Lonergan-JA; Begg-C; Parkinson-DR
p. 147
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Risk assessment for neurobehavioral toxicity
McMillan-DE
p. 155
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Issues in biochemical applications to risk assessment: are short-term tests predictive of in vivo tumorigenicity?
Tennant-RW
p. 163
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Issues of biochemical applications to risk assessment: how should the MTD be selected for chronic bioassays?
Kociba-RJ
p. 169
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Issues in biochemical applications to risk assessment: how do we evaluate individual components of multistage models?
Anderson-MW
p. 175
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Issues in biochemical applications to risk assessment: can in vitro studies assist us in species extrapolation?
Strom-SC
p. 181
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Issues in biochemical applications to risk assessment: how do we predict toxicity of complex mixtures?
Albert-RE
p. 185
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Issues in biochemical applications to risk assessment: when can lymphocytes be used as surrogate markers?
Lucier-GW; Thompson-CL
p. 187
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Diagnosing the tight building syndrome
Rogers-SA
p. 195
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Cytotoxic effects of singlet oxygen
Schiff-LJ; Eisenberg-WC; Dziuba-J; Taylor-K; Moore-SJ
p. 199
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Studies of carcinogenicity of sodium chlorite in B6C3F1 mice
Yokose-Y; Uchida-K; Nakae-D; Shiraiwa-K; Yamamoto-K; Konishi-Y
p. 205
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Ranking the potential carcinogenic hazards to workers from exposures to chemicals that are tumorigenic in rodents
Gold-LS; Backman-GM; Hooper-NK; Peto-R
p. 211
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Cancer incidence among welders: possible effects of exposure to extremely low frequency electromagnetic radiation (ELF) and to welding fumes
Stern-RM
p. 221
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