FAQs : Multi-disciplinary Approach to the Study of Chronic Pelvic pain (MAPP) Research Network (U01): RFA-DK-07-003
See Below for Newly Added FAQs (11/21/2007)
(NOTE: This Sheet should not be considered authoritative, it includes some relevant items from the RFA but is not all inclusive. Applicant must adhere to all requirements as written in the below referenced RFA).
WHAT IS THE PURPOSE OF RFA?:
To develop a multi-center cooperative research network focusing on the urologic chronic pelvic pain syndromes, specifically Interstitial Cystitis/Painful Bladder Syndrome and Chronic Prostatitis/Chronic Pelvic Pain Syndrome, and their major associated co-morbidities.
MAPP Network research priorities include: (1) Studies of individual patients to identify disease phenotypes, (2) Targeted epidemiologic studies to examine the natural history of disease, and (3) Basic science studies addressing the underlying pathology of disease.
WHERE CAN I FIND THIS RFA?:
The MAPP Research Network funding announcement (RFA-DK-07-003) is available at:http://grants.nih.gov/grants/guide/rfa-files/RFA-DK-07-003.html.
WHAT ARE THE SEPARATE COMPONENTS AND FUNDING AMOUNTS OF THE MAPP?:
The MAPP Research Network will consist of:
- Discovery Sites - funded at $1,000,000 per year (total costs) for five years.
- Data Coordinating/Administrative Core - funded at $750,000 per year (total costs) for five years.
- Tissue Analysis and Technology Core - funded at $750,000 per year (total costs) for five years.
WHAT NEEDS TO BE INCLUDED IN A DISCOVERY SITE?:
- At least three but not more than five individual Research Projects, each headed by a Project Leader.
- Each of the three major Research Priorities (phenotyping of the urologic chronic pelvic pain syndrome patients; targeted epidemiology of relevant patient populations; and, the basic science of underlying disease pathology) must be addressed by at least one of the Research Projects.
- At least one Research Project must include collaborations with other Discovery Sites.
MAY AN APPLICANT APPLY MORE THAN ONCE?:
- See the NOTICE in the NIH Guide for a REVISED POLICY on this point.
- An investigator may be listed as a Director or Co-Director on only one application responding to this RFA.
- An investigator may be listed on more than one application (except as a Director/Co-Director, as noted above) provided that the investigator engages in distinct and non-duplicated scientific efforts in the different applications.
WHO MAY APPLY?:
- Applications may be from either U.S. or non-U.S. Institutions.
- Collaborative relationships between institutions are highly encouraged.
- A Discovery or Core Site Director may be either a clinical, translational, or a basic scientist with appropriate experience.
- The Multiple Principal Investigator concept may be used (thus allowing Co-Directors).
- Relevant clinical urology expertise (including a track record of patient recruitment) must be within each Discovery Site either as a Director or Leader(s) of one or more individual research project (i.e. the overall Discovery Site Director does not need to be a urologist).
KEY RFA DATES:
Letters of Intent Receipt Date: December 17, 2007
Application Receipt Date: January 9, 2008
Earliest Anticipated Start Date: July 1, 2008
NEWLY ADDED FAQS(11/21/2007)
WHAT IS THE APPLICATION FORMAT, PAGE LIMITS, ETC, FOR DISCOVERY SITE AND CORE SITE APPLICATIONS?:
MAPP RFA U01 applications will follow the same general format as NIDDK P01 applications (see RFA text and the P01 website listed in the RFA for specific format, page limits, etc). NOTE: For CORE applications “Section F. Research Projects” may be omitted.
DOES A MAPP DISCOVERY SITE HAVE TO FOCUS ON BOTH IC/PBS AND CP/CPPS?:
The application must focus on either or both IC/PBS and CP/CPPS. The application must also address the potential relationship between IC/PBS and/or CP/CPPS with possible co-morbid conditions, as described in the RFA.
CAN PILOT CLINICAL TRIAL/INTERVENTIONS BE PART OF A PROPOSAL?
No, the MAPP RFA is not soliciting clinical intervention/treatment efforts.
CAN I PARTICIPATE IN MORE THAN ONE MAPP RFA APPLICATION?
Yes, provided you adhere to NOT-08-003.
CAN I SUBMIT A SEPARATE APPLICATION (E.G. R01) ON MY MAPP PROJECT AT THE SAME TIME AS MY MAPP U01?
No, this may jeopardize the acceptance of your MAPP RFA application.
HOW DO I PROPOSE A TRANS-MAPP PROJECT WITHOUT KNOWING WHAT OTHER SITES WILL BE FUNDED
Your proposed Trans-MAPP Network Project(s) should include efforts that you envision benefiting from the collaborative effort of multiple MAPP Sites. You do not need to name specific MAPP Discovery Site applicants. All proposed Trans-MAPP Projects will be evaluated when the group begins to meet and the high priority study designs will be adopted by the Network.
FOR ADDITIONAL INFORMATION DIRECT INQUIRIES (PREFERABLY BY E-MAIL) TO:
Dr. Chris Mullins
Director of Urology Basic Cell Biology Programs
Phone: (301) 451-4902
E-mail: MullinsC@extra.niddk.nih.gov
Dr. Lee Nyberg
Director of Urology Programs
Phone: (301) 594-7717
E-mail: NybergL@mail.nih.gov
NIDDK hosted an in-person information session in Bethesda on November 5th, 2007 .
Page last updated: November 21, 2007
