Emory Epithelial Pathobiology Research Development Center
Director: Vincent W. Yang, M.D. Ph.D.
Co-Directors: Andrew S. Neish, M.D., Asma Nusrat, M.D., Charles A. Parkos, M.D., Ph.D., Ifor R. Williams, M.D.
The "Emory Epithelial Pathobiology Research Development Center" supports the research programs of nine established investigators from four departments of the Emory University School of Medicine. In addition, the Center supports the research activities of junior members who are considered new investigators. This group of investigators shares a central research theme of understanding the biology and pathobiology of the epithelium in the digestive tract. In particular, projects supported by the Center concentrate on understanding the physiologic, inflammatory, and proliferative responses of the gut epithelium. The GOAL of the DDRDC is to provide shared resources and facilities for this group of highly focused investigators in order to enhance research capability, promote new facilities for this group of highly focused investigators in order to enhance research capability, promote new research directions, and foster strong interactions and collaborations among researchers. The Center supports a dedicated cDNA microarray facility with bioinformatics and biostatistical support and focuses on the profiling of gene expression relevant to epithelial biology and pathobiology of the digestive system. Also supported is a state -of-the-art confocal microscope and a fluorescence activated cell sorter to enhance investigators' ability for image analysis. Center investigators also have access to specialized permeable culture support (transwells) for experiments involving the polarized epithelial phenotype as well as a facility to support the generation of monoclonal antibodies. The Center cores are located in the newly completed Whitehead Biomedical Research Building on the main campus of the Emory University. The majority of participating investigators' laboratories are located in the same building and the remainder is located within easily accessible distance. The Center serves to enhance the research capabilities of the involved investigators and help further foster the development of a strong epithelial biology and pathobiology group at Emory with a strong research focus on areas within the mission supported by the National Institute of Diabetes, Digestive and Kidney Diseases (NIDDK).
- Gene Expression Analysis Core
- Image Analysis Core
- Cell Culture and Monoclonal Antibody Core
Page last updated: November 25, 2008