Publicly available data from the NCI Yeast Anticancer Drug Screen

Stage2 tested compounds that inhibit the growth of the rad52 mutant strain

The table below lists data for 153 compounds that inhibit the growth of the rad52 mutant strain by at least 70% at the dose indicated.

Compounds that inhibit only the rad52 mutant strain by at least 70% for at least one dose are at the top of the table.

Compounds that inhibit the rad52 mutant strain PLUS several other strains by at least 70% are listed further down in the table. Caution: rad52 is not necessarily the most sensitive strain when multiple strains are listed.

Previous 300 compounds that inhibit rad52

Inhibited Strains

NSC/name 1.2 microM 3.7 microM 11 microM 33 microM 100 microM Stage2 Graphs NCI 60 Human Tumor Cell Data 3D Structure of Compound Basic Chemical Data
324047
    rad18 rad18 rad50EPP+ rad18 rad52 rad50EPP+ sgs1 Stage2 Graphs for 324047   3D Structure for 324047 Basic Chemical Data for 324047
356235
L-CYSTEINE, HOMOPOLYMER,
DIPHENYLTIN COMPLEX
      rad14 rad18 rad50 rad52 mgt1 mlh1 sgs1 wt2 CLN2oe bub3 mec2 rad14 rad18 rad50 rad52 wt1 mgt1 mlh1 sgs1 wt2 Stage2 Graphs for 356235     Basic Chemical Data for 356235
360702
1-PIPERAZINECARBOXYLIC
ACID, 4-FORMYL-, 2-[2,5-BIS(1-
AZIRIDINYL)-4-METHYL-3,6-DIOXO-
1,4-CYCLOHEXADIE
    rad18 rad18 rad14 rad18 rad50 rad52 Stage2 Graphs for 360702   3D Structure for 360702 Basic Chemical Data for 360702
372391
        rad14 rad50 rad52 sgs1 Stage2 Graphs for 372391 60 Cell Data for 372391   Basic Chemical Data for 372391
374986
      rad14 rad18 rad50 rad52 mlh1 rad50EPP+ sgs1 wt2 mec2 rad14 rad18 rad50 rad52 wt1 mgt1 mlh1 rad50EPP+ sgs1 wt2 Stage2 Graphs for 374986 60 Cell Data for 374986   Basic Chemical Data for 374986
375508
        bub3 rad18 rad50 rad52 mgt1 mlh1 sgs1 wt2 Stage2 Graphs for 375508     Basic Chemical Data for 375508
379587
QUINOMETHIONATE
    rad14 rad18 rad50 rad52 mlh1 rad50EPP+ sgs1 wt2 all all Stage2 Graphs for 379587 60 Cell Data for 379587   Basic Chemical Data for 379587
380271
    rad18 rad50 rad52 sgs1 CLN2oe bub3 mec2 rad14 rad18 rad50 rad52 mgt1 mlh1 rad50EPP+ sgs1 all Stage2 Graphs for 380271 60 Cell Data for 380271 3D Structure for 380271 Basic Chemical Data for 380271
380803
rad14 rad18 rad50 rad52 mlh1 sgs1 wt2 bub3 rad14 rad18 rad50 rad52 wt1 mgt1 mlh1 rad50EPP+ sgs1 wt2 bub3 mec2 rad14 rad18 rad50 rad52 wt1 mgt1 mlh1 rad50EPP+ sgs1 wt2 all all Stage2 Graphs for 380803   3D Structure for 380803 Basic Chemical Data for 380803
380804
  rad14 sgs1 rad14 rad18 rad50 rad52 mlh1 sgs1 wt2 rad14 rad18 rad50 rad52 wt1 mgt1 mlh1 sgs1 wt2 bub3 rad14 rad18 rad50 rad52 wt1 mgt1 mlh1 sgs1 wt2 Stage2 Graphs for 380804 60 Cell Data for 380804   Basic Chemical Data for 380804
382767
rad18 rad18 rad18 rad50EPP+ rad18 rad52 rad50EPP+ sgs1 rad14 rad18 rad52 rad50EPP+ sgs1 Stage2 Graphs for 382767 60 Cell Data for 382767   Basic Chemical Data for 382767
400078
    rad18 rad18 rad52 rad50EPP+ sgs1 all Stage2 Graphs for 400078 60 Cell Data for 400078   Basic Chemical Data for 400078
400979
ILLUDIN S
  rad18 rad18 rad18 rad18 rad52 sgs1 Stage2 Graphs for 400979 60 Cell Data for 400979 3D Structure for 400979 Basic Chemical Data for 400979
401101
    rad18 rad18 rad14 rad18 rad50 rad52 mlh1 sgs1 wt2 Stage2 Graphs for 401101 60 Cell Data for 401101 3D Structure for 401101 Basic Chemical Data for 401101
401357
    rad50EPP+ rad18 rad50 rad52 rad50EPP+ sgs1 mec2 rad14 rad18 rad50 rad52 mlh1 rad50EPP+ sgs1 Stage2 Graphs for 401357   3D Structure for 401357 Basic Chemical Data for 401357
402344
        rad14 rad50 rad52 rad50EPP+ sgs1 Stage2 Graphs for 402344 60 Cell Data for 402344 3D Structure for 402344 Basic Chemical Data for 402344
402409
    rad50EPP+ bub3 rad14 rad50 rad52 mgt1 mlh1 rad50EPP+ sgs1 wt2 all Stage2 Graphs for 402409   3D Structure for 402409 Basic Chemical Data for 402409
402756
1-METHOXYPHENAZINE
      rad18 rad50 rad52 mgt1 rad50EPP+ all Stage2 Graphs for 402756 60 Cell Data for 402756 3D Structure for 402756 Basic Chemical Data for 402756
403126
        CLN2oe rad18 rad50 rad52 Stage2 Graphs for 403126   3D Structure for 403126 Basic Chemical Data for 403126
403197
        rad14 rad18 rad52 mgt1 mlh1 sgs1 wt2 Stage2 Graphs for 403197   3D Structure for 403197 Basic Chemical Data for 403197
403546
bub3 bub3 rad18 rad50 bub3 rad18 rad50 rad50EPP+ bub3 rad18 rad50 rad52 rad50EPP+ bub3 rad18 rad50 rad52 mlh1 rad50EPP+ Stage2 Graphs for 403546 60 Cell Data for 403546 3D Structure for 403546 Basic Chemical Data for 403546
403831
    rad14 rad50 rad52 sgs1 all all Stage2 Graphs for 403831 60 Cell Data for 403831   Basic Chemical Data for 403831
404141
  rad18 rad18 rad52 sgs1 all all Stage2 Graphs for 404141 60 Cell Data for 404141 3D Structure for 404141 Basic Chemical Data for 404141
404917
  rad18 rad50 rad52 sgs1 CLN2oe bub3 mec2 rad14 rad18 rad50 rad52 wt1 mgt1 mlh1 sgs1 wt2 CLN2oe bub3 mec2 rad14 rad18 rad50 rad52 wt1 mgt1 mlh1 sgs1 wt2 CLN2oe bub3 mec2 rad14 rad18 rad50 rad52 wt1 mgt1 mlh1 sgs1 wt2 Stage2 Graphs for 404917   3D Structure for 404917 Basic Chemical Data for 404917
405961
        rad14 rad18 rad50 rad52 mgt1 mlh1 sgs1 wt2 Stage2 Graphs for 405961 60 Cell Data for 405961 3D Structure for 405961 Basic Chemical Data for 405961
406433
  rad18 rad50 rad52 sgs1 all all all Stage2 Graphs for 406433 60 Cell Data for 406433 3D Structure for 406433 Basic Chemical Data for 406433
407072
        rad14 rad18 rad52 mlh1 sgs1 wt2 Stage2 Graphs for 407072 60 Cell Data for 407072 3D Structure for 407072 Basic Chemical Data for 407072
529861
ASPARTIC ACID, N-[P-[[(2,4-
DIAMINO-5-CHLORO-6-QUINAZOLINYL)
METHYL]AMINO]BENZOYL]-, L
    mec2 mec2 rad18 rad52 bub3 mec2 rad14 rad18 rad50 rad52 wt1 Stage2 Graphs for 529861   3D Structure for 529861 Basic Chemical Data for 529861
603854
  mec2 rad52 sgs1 CLN2oe bub3 mec2 rad14 rad18 rad50 rad52 wt1 mgt1 mlh1 sgs1 wt2 all all Stage2 Graphs for 603854 60 Cell Data for 603854 3D Structure for 603854 Basic Chemical Data for 603854
606843
SONDERIANIN
      rad14 rad18 rad52 mgt1 mlh1 sgs1 wt2 CLN2oe bub3 mec2 rad14 rad18 rad50 rad52 mgt1 mlh1 sgs1 Stage2 Graphs for 606843   3D Structure for 606843 Basic Chemical Data for 606843
607301
L-GLUTAMIC ACID, N-[4-[[(2,4-
DIAMINO-6-PTERIDINYL) METHYL]
AMINO]-3-FLUOROBENZOYL]-,
TRIFLUOROACETATE
    mec2 mec2 rad18 rad52 bub3 mec2 rad14 rad18 rad50 rad52 wt1 Stage2 Graphs for 607301 60 Cell Data for 607301 3D Structure for 607301 Basic Chemical Data for 607301
613038
        rad18 rad52 sgs1 Stage2 Graphs for 613038   3D Structure for 613038 Basic Chemical Data for 613038
621482
rad18 rad52 sgs1 rad18 rad50 rad52 mlh1 sgs1 wt2 mec2 rad14 rad18 rad50 rad52 mgt1 mlh1 rad50EPP+ sgs1 wt2 mec2 rad14 rad18 rad50 rad52 mgt1 mlh1 rad50EPP+ sgs1 wt2 mec2 rad14 rad18 rad50 rad52 mgt1 mlh1 rad50EPP+ sgs1 wt2 Stage2 Graphs for 621482 60 Cell Data for 621482 3D Structure for 621482 Basic Chemical Data for 621482
626105
        bub3 mec2 rad50 rad52 rad50EPP+ Stage2 Graphs for 626105   3D Structure for 626105 Basic Chemical Data for 626105
631058
5-BETA-ANDROSTANO[3,4-C]-
1',2',5'-OXADIAZOL-17-ONE
      rad14 rad18 rad50 rad52 mgt1 mlh1 sgs1 wt2 bub3 mec2 rad14 rad18 rad50 rad52 mgt1 mlh1 sgs1 wt2 Stage2 Graphs for 631058 60 Cell Data for 631058 3D Structure for 631058 Basic Chemical Data for 631058
637660
    rad18 rad50 rad52 rad50EPP+ sgs1 CLN2oe bub3 mec2 rad14 rad18 rad50 rad52 mgt1 mlh1 rad50EPP+ sgs1 wt2 all Stage2 Graphs for 637660 60 Cell Data for 637660 3D Structure for 637660 Basic Chemical Data for 637660
644221
      rad50 bub3 rad50 rad52 mlh1 Stage2 Graphs for 644221 60 Cell Data for 644221 3D Structure for 644221 Basic Chemical Data for 644221
647045
ACETATOBIS(1,3-DIPHENYL
PROPANE-1,3-DIONATO)SAMARIUM(III)
    bub3 rad14 rad50 rad52 all all Stage2 Graphs for 647045 60 Cell Data for 647045 3D Structure for 647045 Basic Chemical Data for 647045
647271
        rad14 rad18 rad50 rad52 mlh1 sgs1 wt2 Stage2 Graphs for 647271 60 Cell Data for 647271 3D Structure for 647271 Basic Chemical Data for 647271
653551
      rad18 rad52 sgs1 CLN2oe bub3 mec2 rad18 rad50 rad52 wt1 mgt1 mlh1 sgs1 wt2 Stage2 Graphs for 653551 60 Cell Data for 653551 3D Structure for 653551 Basic Chemical Data for 653551
656669
      bub3 rad18 rad50 rad52 mgt1 mlh1 sgs1 wt2 CLN2oe bub3 mec2 rad14 rad18 rad50 rad52 wt1 mgt1 mlh1 sgs1 wt2 Stage2 Graphs for 656669 60 Cell Data for 656669 3D Structure for 656669 Basic Chemical Data for 656669
657602
      CLN2oe rad18 rad50 rad52 mlh1 sgs1 wt2 CLN2oe bub3 mec2 rad14 rad18 rad50 rad52 wt1 mgt1 mlh1 sgs1 wt2 Stage2 Graphs for 657602 60 Cell Data for 657602 3D Structure for 657602 Basic Chemical Data for 657602
658345
      rad18 mec2 rad18 rad50 rad52 mgt1 mlh1 sgs1 wt2 Stage2 Graphs for 658345 60 Cell Data for 658345 3D Structure for 658345 Basic Chemical Data for 658345
658928
BIS(2-CHLOROETHYL)-N-METHYL
-N-(5-METHYL-2-NITROBENZYL)
AMMONIUM CHLORIDE
  rad18 rad14 rad18 rad50 rad52 rad50EPP+ mec2 rad14 rad18 rad50 rad52 rad50EPP+ sgs1 bub3 mec2 rad14 rad18 rad50 rad52 wt1 mgt1 mlh1 rad50EPP+ sgs1 wt2 Stage2 Graphs for 658928 60 Cell Data for 658928 3D Structure for 658928 Basic Chemical Data for 658928
658929
BIS(2-CHLOROETHYL)-N-METHYL
-N-(3-METHYL-2-NITROBENZYL)
AMMONIUM CHLORIDE
  rad18 rad14 rad18 rad50 rad52 rad50EPP+ mec2 rad14 rad18 rad50 rad52 rad50EPP+ sgs1 all Stage2 Graphs for 658929 60 Cell Data for 658929 3D Structure for 658929 Basic Chemical Data for 658929
660019
      rad50EPP+ rad14 rad18 rad50 rad52 mlh1 rad50EPP+ sgs1 wt2 Stage2 Graphs for 660019 60 Cell Data for 660019 3D Structure for 660019 Basic Chemical Data for 660019
663314
BIS(2-CHLOROETHYL)-N-
METHYL-N(3-METHOXY-2-NITROBENZYL)
AMMONIUM CHLORIDE
    rad18 rad14 rad18 rad50 rad52 rad50EPP+ rad14 rad18 rad50 rad52 rad50EPP+ sgs1 Stage2 Graphs for 663314 60 Cell Data for 663314 3D Structure for 663314 Basic Chemical Data for 663314
663315
BIS(2-CHLOROETHYL)-N-METHYL
-N-(5-METHOXY-2-NITROBENZYL)
AMMONIUM CHLORIDE
    rad18 rad14 rad18 rad50 rad52 rad50EPP+ mec2 rad14 rad18 rad50 rad52 rad50EPP+ sgs1 Stage2 Graphs for 663315 60 Cell Data for 663315 3D Structure for 663315 Basic Chemical Data for 663315
663650
      rad14 rad18 rad50 rad52 all Stage2 Graphs for 663650 60 Cell Data for 663650 3D Structure for 663650 Basic Chemical Data for 663650
665109
rad18 rad18 rad52 sgs1 CLN2oe bub3 mec2 rad14 rad18 rad50 rad52 wt1 mgt1 mlh1 sgs1 wt2 all CLN2oe bub3 mec2 rad14 rad18 rad50 rad52 wt1 mgt1 mlh1 sgs1 wt2 Stage2 Graphs for 665109 60 Cell Data for 665109 3D Structure for 665109 Basic Chemical Data for 665109
665631
bub3 bub3 bub3 bub3 bub3 rad52 sgs1 Stage2 Graphs for 665631 60 Cell Data for 665631 3D Structure for 665631 Basic Chemical Data for 665631
666398
    CLN2oe rad18 rad50 rad52 wt2 CLN2oe bub3 mec2 rad14 rad18 rad50 rad52 wt1 mgt1 sgs1 wt2 CLN2oe mec2 rad14 rad18 rad50 rad52 wt1 mgt1 mlh1 sgs1 wt2 Stage2 Graphs for 666398 60 Cell Data for 666398 3D Structure for 666398 Basic Chemical Data for 666398
669160
1-AZIDO-2-(2-PYRIDYL)-
PHENALEN-3-ONE
      rad50EPP+ CLN2oe rad18 rad50 rad52 rad50EPP+ Stage2 Graphs for 669160 60 Cell Data for 669160 3D Structure for 669160 Basic Chemical Data for 669160
671799
        CLN2oe rad14 rad52 mgt1 mlh1 sgs1 wt2 Stage2 Graphs for 671799   3D Structure for 671799 Basic Chemical Data for 671799
672045
PROPANIMIDOYL CHLORIDE, N-
[[[(4-FLUOROPHENYL)AMINO]
CARBONYL]OXY]-2-METHYL-
      mgt1 sgs1 wt2 bub3 mec2 rad50 rad52 mgt1 mlh1 rad50EPP+ sgs1 wt2 Stage2 Graphs for 672045 60 Cell Data for 672045 3D Structure for 672045 Basic Chemical Data for 672045
677438
ALDRITHIOL-2
    bub3 mec2 rad52 rad50EPP+ all all Stage2 Graphs for 677438   3D Structure for 677438 Basic Chemical Data for 677438
683863
HMAF
  rad18 rad18 rad18 rad18 rad50 rad52 sgs1 Stage2 Graphs for 683863 60 Cell Data for 683863 3D Structure for 683863 Basic Chemical Data for 683863
684973
      rad50EPP+ rad14 rad18 rad50 rad52 mgt1 mlh1 rad50EPP+ sgs1 wt2 Stage2 Graphs for 684973 60 Cell Data for 684973 3D Structure for 684973 Basic Chemical Data for 684973
685418
        bub3 rad52 sgs1 wt2 Stage2 Graphs for 685418 60 Cell Data for 685418 3D Structure for 685418 Basic Chemical Data for 685418
740
METHOTREXATE
      mec2 mec2 rad14 rad18 rad50 rad52 Stage2 Graphs for 740 60 Cell Data for 740 3D Structure for 740 Basic Chemical Data for 740
3535
      bub3 mec2 rad18 rad52 mgt1 mlh1 sgs1 wt2 CLN2oe bub3 mec2 rad14 rad18 rad50 rad52 wt1 mgt1 mlh1 sgs1 wt2 Stage2 Graphs for 3535 60 Cell Data for 3535   Basic Chemical Data for 3535
23173
      rad18 mec2 rad14 rad18 rad50 rad52 mgt1 mlh1 rad50EPP+ sgs1 wt2 Stage2 Graphs for 23173 60 Cell Data for 23173 3D Structure for 23173 Basic Chemical Data for 23173
23418
    rad14 rad50 sgs1 wt2 CLN2oe bub3 rad14 rad50 rad52 mgt1 mlh1 sgs1 wt2 CLN2oe bub3 rad14 rad18 rad50 rad52 wt1 mgt1 mlh1 sgs1 wt2 Stage2 Graphs for 23418   3D Structure for 23418 Basic Chemical Data for 23418
59937
        bub3 mec2 rad18 rad50 rad52 mlh1 sgs1 wt2 Stage2 Graphs for 59937   3D Structure for 59937 Basic Chemical Data for 59937
59954
DEHYDROABIETIC ACID
    CLN2oe bub3 mec2 rad50 rad52 wt2 CLN2oe bub3 mec2 rad14 rad18 rad50 rad52 wt1 mgt1 mlh1 sgs1 wt2 CLN2oe bub3 mec2 rad14 rad18 rad50 rad52 wt1 mgt1 mlh1 sgs1 wt2 Stage2 Graphs for 59954   3D Structure for 59954 Basic Chemical Data for 59954
76919
2-PYRIDINECARBOXYLIC ACID,
5-AMINO-6-(7-AMINO-1,2,3,4,5,8-
HEXAHYDRO- 5,8-DIOXO-2-
QUINOLINYL)-4-(2-HYDROXY- 3,4-
DIMETHOXYPHENYL)-3-METHYL-
mec2 rad14 rad18 rad50 rad52 mec2 rad14 rad18 rad50 rad52 sgs1 CLN2oe bub3 mec2 rad14 rad18 rad50 rad52 wt1 mgt1 mlh1 rad50EPP+ sgs1 all all Stage2 Graphs for 76919 60 Cell Data for 76919 3D Structure for 76919 Basic Chemical Data for 76919
81222
2,2,2',4'-TETRACHLORO
ACETOPHENONE
      bub3 mec2 rad18 rad50 rad52 mlh1 rad50EPP+ sgs1 wt2 all Stage2 Graphs for 81222   3D Structure for 81222 Basic Chemical Data for 81222
82493
2-PROPANONE, 1,3-
DIMERCAPTO-, SEMICARBAZONE
        rad14 rad18 rad50 rad52 sgs1 Stage2 Graphs for 82493 60 Cell Data for 82493 3D Structure for 82493 Basic Chemical Data for 82493
108308
        bub3 mec2 rad18 rad50 rad52 mlh1 sgs1 wt2 Stage2 Graphs for 108308   3D Structure for 108308 Basic Chemical Data for 108308
111556
NAPHTHALENE, 2-(2-NITROVINYL)-
  mec2 rad14 rad50 rad52 rad50EPP+ sgs1 all all all Stage2 Graphs for 111556   3D Structure for 111556 Basic Chemical Data for 111556
117196
  bub3 rad18 rad52 sgs1 all all all Stage2 Graphs for 117196 60 Cell Data for 117196 3D Structure for 117196 Basic Chemical Data for 117196
119875
CISPLATIN
    rad18 rad18 rad14 rad18 rad50 rad52 rad50EPP+ sgs1 Stage2 Graphs for 119875 60 Cell Data for 119875   Basic Chemical Data for 119875
120231
  bub3 rad14 rad18 rad50 rad52 mgt1 rad50EPP+ sgs1 wt2 all all all Stage2 Graphs for 120231   3D Structure for 120231 Basic Chemical Data for 120231
125066
BLEOMYCIN SULFATE
      rad14 rad18 rad50 rad52 sgs1 all Stage2 Graphs for 125066 60 Cell Data for 125066   Basic Chemical Data for 125066
129266
      rad50EPP+ bub3 mec2 rad50 rad52 rad50EPP+ sgs1 Stage2 Graphs for 129266 60 Cell Data for 129266 3D Structure for 129266 Basic Chemical Data for 129266
131919
      rad50 rad50EPP+ bub3 mec2 rad18 rad50 rad52 mgt1 mlh1 rad50EPP+ sgs1 wt2 Stage2 Graphs for 131919   3D Structure for 131919 Basic Chemical Data for 131919
137044
      rad50EPP+ bub3 rad18 rad52 mgt1 rad50EPP+ Stage2 Graphs for 137044   3D Structure for 137044 Basic Chemical Data for 137044
139346
  rad18 rad18 rad18 rad50 rad50EPP+ rad14 rad18 rad50 rad52 rad50EPP+ sgs1 Stage2 Graphs for 139346   3D Structure for 139346 Basic Chemical Data for 139346
140373
    rad50EPP+ bub3 rad18 rad50 rad52 rad50EPP+ sgs1 all Stage2 Graphs for 140373   3D Structure for 140373 Basic Chemical Data for 140373
141058
  rad18 rad18 rad50 sgs1 rad14 rad18 rad50 rad52 rad50EPP+ sgs1 all Stage2 Graphs for 141058   3D Structure for 141058 Basic Chemical Data for 141058
142226
rad18 rad18 rad18 bub3 rad14 rad18 mgt1 mlh1 sgs1 mec2 rad14 rad18 rad50 rad52 mgt1 mlh1 sgs1 wt2 Stage2 Graphs for 142226   3D Structure for 142226 Basic Chemical Data for 142226
158261
ACRIDINE, 9-FORMYL-
      rad50 rad50EPP+ mec2 rad14 rad18 rad50 rad52 mgt1 mlh1 rad50EPP+ sgs1 wt2 Stage2 Graphs for 158261   3D Structure for 158261 Basic Chemical Data for 158261
173905
PENTANAMIDE, 2-(ACETYL
AMINO)-N-[3-CHLORO-2-OXO-1-(
PHENYLMETHYL)PROPYL]-4-METHYL-
        bub3 mec2 rad18 rad50 rad52 mgt1 mlh1 sgs1 wt2 Stage2 Graphs for 173905 60 Cell Data for 173905 3D Structure for 173905 Basic Chemical Data for 173905
173908
1-NAPHTHALENEPROPANOL,
ALPHA-ETHENYLDECAHYDRO-3-
HYDROXY-ALPHA,5,5,8A-TETRA
METHYL-2-METHYLENE- (9
        rad14 rad18 rad50 rad52 sgs1 Stage2 Graphs for 173908 60 Cell Data for 173908 3D Structure for 173908 Basic Chemical Data for 173908
177383
TOLYPOMYCIN Y
        bub3 mec2 rad14 rad50 rad52 mgt1 mlh1 sgs1 wt2 Stage2 Graphs for 177383 60 Cell Data for 177383   Basic Chemical Data for 177383
191250
        rad18 rad50 rad52 mlh1 rad50EPP+ sgs1 Stage2 Graphs for 191250   3D Structure for 191250 Basic Chemical Data for 191250
201685
        bub3 mec2 rad14 rad50 rad52 mgt1 mlh1 rad50EPP+ wt2 Stage2 Graphs for 201685   3D Structure for 201685 Basic Chemical Data for 201685
203153
      bub3 rad14 rad18 rad50 rad52 rad50EPP+ sgs1 wt2 all Stage2 Graphs for 203153   3D Structure for 203153 Basic Chemical Data for 203153
240587
BENZENEBUTANOIC ACID, 4-[BIS
(2-CHLOROETHYL)AMINO]-3,5-DIIODO-
      CLN2oe bub3 rad18 rad52 mgt1 mlh1 sgs1 wt2 CLN2oe bub3 mec2 rad14 rad18 rad50 rad52 wt1 mgt1 mlh1 sgs1 wt2 Stage2 Graphs for 240587   3D Structure for 240587 Basic Chemical Data for 240587
268665
        bub3 rad14 rad18 rad50 rad52 mgt1 sgs1 wt2 Stage2 Graphs for 268665 60 Cell Data for 268665 3D Structure for 268665 Basic Chemical Data for 268665
268965
BENZALDEHYDE, 4-[BIS[2-[
(METHYLSULFONYL)OXY]ETHYL]AMINO]-
rad18 rad18 rad18 mec2 rad14 rad18 rad50 rad52 sgs1 mec2 rad14 rad18 rad50 rad52 mgt1 mlh1 sgs1 wt2 Stage2 Graphs for 268965 60 Cell Data for 268965 3D Structure for 268965 Basic Chemical Data for 268965
281617
ETHANOL, 2,2'[[3-METHYL-4-
[[[4-[5-METHYL-2-(PHENYLMETHYL)-
4-THIAZOLYL]PHENYL]IMINO]
METHYL]PHENYL]IMI
  rad18 mec2 rad14 rad18 rad50 rad52 CLN2oe bub3 mec2 rad14 rad18 rad50 rad52 wt1 mgt1 mlh1 sgs1 wt2 all Stage2 Graphs for 281617 60 Cell Data for 281617 3D Structure for 281617 Basic Chemical Data for 281617
281818
ETHANOL, 2,2'-[[3-METHYL-4-
[[[4-[2-(4-PROPOXYPHENYL]-4-
THIAZOLYL]PHENYL]IMINO]METHYL]
PHENYL]IMINO]BIS-,
DIMETHANESULFONATE (ESTER)
    rad18 mec2 rad18 mec2 rad14 rad18 rad50 rad52 mgt1 mlh1 sgs1 wt2 Stage2 Graphs for 281818 60 Cell Data for 281818 3D Structure for 281818 Basic Chemical Data for 281818
286699
    rad18 rad50EPP+ CLN2oe bub3 rad18 rad50 rad52 rad50EPP+ bub3 rad18 rad50 rad52 rad50EPP+ Stage2 Graphs for 286699   3D Structure for 286699 Basic Chemical Data for 286699
290963
  rad50 rad52 mgt1 mlh1 rad50EPP+ sgs1 all all all Stage2 Graphs for 290963   3D Structure for 290963 Basic Chemical Data for 290963
319662
  rad50EPP+ rad50EPP+ bub3 mec2 rad18 rad52 rad50EPP+ all Stage2 Graphs for 319662   3D Structure for 319662 Basic Chemical Data for 319662
328201
      rad14 rad18 rad50 rad52 sgs1 all Stage2 Graphs for 328201 60 Cell Data for 328201   Basic Chemical Data for 328201
329226
rad14 rad18 rad50 rad52 rad50EPP+ sgs1 rad14 rad18 rad50 rad52 rad50EPP+ sgs1 rad14 rad18 rad50 rad52 rad50EPP+ sgs1 rad14 rad18 rad50 rad52 rad50EPP+ sgs1 mec2 rad14 rad18 rad50 rad52 rad50EPP+ sgs1 Stage2 Graphs for 329226 60 Cell Data for 329226 3D Structure for 329226 Basic Chemical Data for 329226
331269
OXIRANE, 2,2'-[2,3-NAPHTHAL
ENDIYLBIS(OXYMETHYLENE)]BIS-
    sgs1 rad18 sgs1 rad14 rad18 rad50 rad52 rad50EPP+ sgs1 Stage2 Graphs for 331269 60 Cell Data for 331269 3D Structure for 331269 Basic Chemical Data for 331269
335766
QUINAZOLINE, 4-ETHYL-6-
METHOXY-7-(OXIRANYLMETHOXY)-
rad18 rad18 rad18 rad50 sgs1 mec2 rad14 rad18 rad50 rad52 sgs1 mec2 rad14 rad18 rad50 rad52 rad50EPP+ sgs1 wt2 Stage2 Graphs for 335766 60 Cell Data for 335766 3D Structure for 335766 Basic Chemical Data for 335766
351239
BENZENE, 1,4-DICHLORO-2,5-
BIS(2-NITROETHENYL)-
    bub3 rad14 rad18 rad50 rad52 bub3 mec2 rad14 rad18 rad50 rad52 mgt1 mlh1 wt2 CLN2oe bub3 mec2 rad14 rad18 rad50 rad52 mgt1 mlh1 Stage2 Graphs for 351239 60 Cell Data for 351239 3D Structure for 351239 Basic Chemical Data for 351239
357777
    bub3 rad14 rad18 rad50 rad52 mlh1 sgs1 wt2 all all Stage2 Graphs for 357777 60 Cell Data for 357777   Basic Chemical Data for 357777
373980
rad18 rad14 rad18 rad14 rad18 rad52 rad50EPP+ sgs1 rad14 rad18 rad50 rad52 rad50EPP+ sgs1 mec2 rad14 rad18 rad50 rad52 rad50EPP+ sgs1 Stage2 Graphs for 373980 60 Cell Data for 373980   Basic Chemical Data for 373980
380725
PYRROLO[2,1-B]THIAZOLE-6,7-
DIMETHANOL, 5-(3,4-DICHLORO
PHENYL)-, BIS(METHYL
CARBAMATE) (ESTER)
        rad14 rad18 rad50 rad52 sgs1 Stage2 Graphs for 380725 60 Cell Data for 380725 3D Structure for 380725 Basic Chemical Data for 380725
382001
2-PROPEN-1-ONE, 2-[(DIMETHYL
AMINO)METHYL]-1-(2,5-
DIMETHYL PHENYL)-, HYDROCHLORIDE
    bub3 mec2 rad18 rad52 mgt1 mlh1 sgs1 wt2 all all Stage2 Graphs for 382001 60 Cell Data for 382001   Basic Chemical Data for 382001
382770
rad18 rad50EPP+ mec2 rad18 rad50 rad52 rad50EPP+ sgs1 mec2 rad14 rad18 rad50 rad52 rad50EPP+ sgs1 mec2 rad14 rad18 rad50 rad52 rad50EPP+ sgs1 CLN2oe bub3 mec2 rad14 rad18 rad50 rad52 mgt1 mlh1 rad50EPP+ sgs1 wt2 Stage2 Graphs for 382770 60 Cell Data for 382770   Basic Chemical Data for 382770
400222
1-MORPHOLINECARBAMIC
ACID, DITHIO-, MORPHOLINE SALT
mec2 rad18 rad50 rad52 rad50EPP+ sgs1 rad50EPP+ rad50EPP+ rad50EPP+ rad18 mlh1 rad50EPP+ Stage2 Graphs for 400222   3D Structure for 400222 Basic Chemical Data for 400222
400526
        bub3 mec2 rad14 rad50 rad52 mgt1 rad50EPP+ sgs1 wt2 Stage2 Graphs for 400526   3D Structure for 400526 Basic Chemical Data for 400526
400594
    rad50EPP+ rad50EPP+ rad18 rad50 rad52 mlh1 rad50EPP+ sgs1 Stage2 Graphs for 400594     Basic Chemical Data for 400594
402799
      bub3 rad18 rad50 rad52 mgt1 mlh1 rad50EPP+ sgs1 bub3 rad14 rad18 rad50 rad52 mgt1 mlh1 rad50EPP+ sgs1 wt2 Stage2 Graphs for 402799   3D Structure for 402799 Basic Chemical Data for 402799
403805
    rad50EPP+ bub3 rad18 rad50 rad52 rad50EPP+ sgs1 all Stage2 Graphs for 403805 60 Cell Data for 403805 3D Structure for 403805 Basic Chemical Data for 403805
405166
    mec2 rad14 rad18 rad50 rad52 mgt1 rad50EPP+ sgs1 wt2 mec2 rad14 rad18 rad50 rad52 wt1 mgt1 mlh1 rad50EPP+ sgs1 wt2 bub3 mec2 rad14 rad18 rad50 rad52 wt1 mgt1 mlh1 rad50EPP+ sgs1 wt2 Stage2 Graphs for 405166   3D Structure for 405166 Basic Chemical Data for 405166
406159
      rad50EPP+ mec2 rad14 rad50 rad52 rad50EPP+ sgs1 Stage2 Graphs for 406159 60 Cell Data for 406159 3D Structure for 406159 Basic Chemical Data for 406159
407756
      rad18 rad14 rad18 rad50 rad52 rad50EPP+ sgs1 Stage2 Graphs for 407756   3D Structure for 407756 Basic Chemical Data for 407756
408050
    rad18 rad18 rad50EPP+ rad14 rad18 rad52 rad50EPP+ sgs1 Stage2 Graphs for 408050 60 Cell Data for 408050 3D Structure for 408050 Basic Chemical Data for 408050
408542
      mec2 rad14 rad18 rad50 rad52 mgt1 mlh1 rad50EPP+ sgs1 wt2 all Stage2 Graphs for 408542   3D Structure for 408542 Basic Chemical Data for 408542
409425
1,6-DIMETHYL-1,6-DINITROSO
BIUREA
rad18 rad18 rad18 rad18 rad50 rad52 mgt1 rad50EPP+ sgs1 mec2 rad18 rad50 rad52 mgt1 rad50EPP+ sgs1 Stage2 Graphs for 409425 60 Cell Data for 409425 3D Structure for 409425 Basic Chemical Data for 409425
610190
6H-PYRIDO[4,3-B]CARBAZOLE-
5-METHANOL, 11-METHYL-,
METHYLCARBAMATE (ESTER)
rad18 rad14 rad18 rad50 rad52 sgs1 mec2 rad14 rad18 rad50 rad52 sgs1 mec2 rad14 rad18 rad50 rad52 sgs1 mec2 rad14 rad18 rad50 rad52 sgs1 Stage2 Graphs for 610190 60 Cell Data for 610190 3D Structure for 610190 Basic Chemical Data for 610190
614300
        bub3 mec2 rad14 rad52 mgt1 mlh1 rad50EPP+ sgs1 wt2 Stage2 Graphs for 614300   3D Structure for 614300 Basic Chemical Data for 614300
616357
        rad14 rad18 rad50 rad52 sgs1 Stage2 Graphs for 616357 60 Cell Data for 616357 3D Structure for 616357 Basic Chemical Data for 616357
617988
DIBENZO[A,C]PHENAZINE-10-
CARBOXAMIDE, N-[2- (DIMETHYL
AMINO)ETHYL]-,
MONOHYDROCHLORIDE
    bub3 rad18 rad50 rad52 rad50EPP+ sgs1 all all Stage2 Graphs for 617988 60 Cell Data for 617988 3D Structure for 617988 Basic Chemical Data for 617988
619443
      sgs1 mec2 rad14 rad18 rad50 rad52 mgt1 mlh1 sgs1 wt2 Stage2 Graphs for 619443 60 Cell Data for 619443   Basic Chemical Data for 619443
631197
9-N-(N'-CHLOROETHYL-N'-ETHYL
-1,4-DIAMINO-BUTYL)2-METHOXY
ACRIDINE DIHYDROCHLORIDE
  rad18 rad14 rad18 rad50 rad52 sgs1 all all Stage2 Graphs for 631197 60 Cell Data for 631197 3D Structure for 631197 Basic Chemical Data for 631197
639860
  rad18 rad18 rad14 rad18 sgs1 rad14 rad18 rad50 rad52 sgs1 Stage2 Graphs for 639860 60 Cell Data for 639860 3D Structure for 639860 Basic Chemical Data for 639860
640543
    CLN2oe mec2 rad14 rad52 mgt1 mlh1 rad50EPP+ sgs1 wt2 all all Stage2 Graphs for 640543 60 Cell Data for 640543 3D Structure for 640543 Basic Chemical Data for 640543
642938
      bub3 bub3 rad18 rad52 sgs1 Stage2 Graphs for 642938 60 Cell Data for 642938 3D Structure for 642938 Basic Chemical Data for 642938
643915
NAPHTHO[2,3-D]OXAZOLE-4,9-
DIONE, 2-(1,1-DIMETHYLETHYL)-
      bub3 rad14 rad18 rad50 rad52 mgt1 mlh1 rad50EPP+ sgs1 wt2 all Stage2 Graphs for 643915 60 Cell Data for 643915 3D Structure for 643915 Basic Chemical Data for 643915
645344
        CLN2oe bub3 mec2 rad52 mgt1 mlh1 sgs1 wt2 Stage2 Graphs for 645344 60 Cell Data for 645344 3D Structure for 645344 Basic Chemical Data for 645344
645571
      CLN2oe bub3 rad18 rad50 rad52 mgt1 mlh1 sgs1 wt2 CLN2oe bub3 mec2 rad14 rad18 rad50 rad52 wt1 mgt1 mlh1 sgs1 wt2 Stage2 Graphs for 645571 60 Cell Data for 645571 3D Structure for 645571 Basic Chemical Data for 645571
646395
rad18 sgs1 rad14 rad18 rad52 sgs1 mec2 rad14 rad18 rad50 rad52 rad50EPP+ sgs1 all all Stage2 Graphs for 646395 60 Cell Data for 646395 3D Structure for 646395 Basic Chemical Data for 646395
648766
ECTEINASCIDIN 743
rad50 mec2 rad14 rad50 rad52 sgs1 all all all Stage2 Graphs for 648766 60 Cell Data for 648766 3D Structure for 648766 Basic Chemical Data for 648766
651079
1H-PYRROLO[1,2-A]BENZ
IMIDAZOLE-5,8-DIONE, 6-(1-
AZIRIDINYL)- 2,3-DIHYDRO-3-
(PROPIONYL)-7-METHYL-
  rad18 rad18 rad18 rad14 rad18 rad50 rad52 sgs1 Stage2 Graphs for 651079 60 Cell Data for 651079 3D Structure for 651079 Basic Chemical Data for 651079
652886
  rad18 rad18 rad14 rad18 rad52 sgs1 mec2 rad14 rad18 rad50 rad52 sgs1 Stage2 Graphs for 652886 60 Cell Data for 652886 3D Structure for 652886 Basic Chemical Data for 652886
652888
rad14 rad18 rad52 sgs1 rad14 rad18 rad50 rad52 sgs1 mec2 rad14 rad18 rad50 rad52 rad50EPP+ sgs1 all all Stage2 Graphs for 652888 60 Cell Data for 652888 3D Structure for 652888 Basic Chemical Data for 652888
657581
    rad18 rad18 mec2 rad14 rad18 rad50 rad52 mgt1 mlh1 sgs1 wt2 Stage2 Graphs for 657581 60 Cell Data for 657581 3D Structure for 657581 Basic Chemical Data for 657581
658830
      bub3 mec2 rad18 rad50 rad52 mgt1 mlh1 rad50EPP+ sgs1 wt2 all Stage2 Graphs for 658830 60 Cell Data for 658830 3D Structure for 658830 Basic Chemical Data for 658830
658926
    rad18 rad50EPP+ rad14 rad18 rad50 rad52 rad50EPP+ sgs1 mec2 rad14 rad18 rad50 rad52 mlh1 rad50EPP+ sgs1 wt2 Stage2 Graphs for 658926 60 Cell Data for 658926 3D Structure for 658926 Basic Chemical Data for 658926
665709
        CLN2oe bub3 rad14 rad50 rad52 mgt1 mlh1 sgs1 wt2 Stage2 Graphs for 665709 60 Cell Data for 665709 3D Structure for 665709 Basic Chemical Data for 665709
666667
        bub3 mec2 rad18 rad50 rad52 mgt1 mlh1 sgs1 wt2 Stage2 Graphs for 666667 60 Cell Data for 666667 3D Structure for 666667 Basic Chemical Data for 666667
666735
rad18 rad18 rad14 rad18 rad50 rad52 sgs1 mec2 rad14 rad18 rad50 rad52 rad50EPP+ sgs1 all Stage2 Graphs for 666735 60 Cell Data for 666735 3D Structure for 666735 Basic Chemical Data for 666735
668525
rad18 rad18 sgs1 rad14 rad18 rad52 rad50EPP+ sgs1 mec2 rad14 rad18 rad50 rad52 rad50EPP+ sgs1 CLN2oe mec2 rad14 rad18 rad50 rad52 wt1 mgt1 mlh1 rad50EPP+ sgs1 wt2 Stage2 Graphs for 668525 60 Cell Data for 668525 3D Structure for 668525 Basic Chemical Data for 668525
668840
  CLN2oe mec2 rad18 rad50 rad52 CLN2oe bub3 mec2 rad14 rad18 rad50 rad52 wt1 mgt1 mlh1 sgs1 wt2 CLN2oe bub3 mec2 rad14 rad18 rad50 rad52 wt1 mgt1 mlh1 sgs1 wt2 CLN2oe bub3 mec2 rad14 rad18 rad50 rad52 wt1 mgt1 mlh1 sgs1 wt2 Stage2 Graphs for 668840 60 Cell Data for 668840 3D Structure for 668840 Basic Chemical Data for 668840
670702
rad18 rad14 rad18 rad52 sgs1 mec2 rad14 rad18 rad50 rad52 sgs1 all all Stage2 Graphs for 670702 60 Cell Data for 670702 3D Structure for 670702 Basic Chemical Data for 670702
673461
      rad18 bub3 mec2 rad18 rad50 rad52 rad50EPP+ Stage2 Graphs for 673461 60 Cell Data for 673461 3D Structure for 673461 Basic Chemical Data for 673461
673794
rad18 rad18 mec2 rad14 rad18 rad52 sgs1 mec2 rad14 rad18 rad50 rad52 mgt1 mlh1 sgs1 wt2 all Stage2 Graphs for 673794 60 Cell Data for 673794 3D Structure for 673794 Basic Chemical Data for 673794
673824
  rad18 rad18 mec2 rad14 rad18 rad50 rad52 mgt1 rad50EPP+ sgs1 wt2 CLN2oe bub3 mec2 rad14 rad18 rad50 rad52 wt1 mgt1 mlh1 sgs1 wt2 Stage2 Graphs for 673824 60 Cell Data for 673824 3D Structure for 673824 Basic Chemical Data for 673824
674699
9-[3-[N-(2-N,N-DIMETHYLAMINO)
ETHYL]AMINOPROPYL]AMINO-
1-NITROACRIDINE.3HCL
rad18 rad14 rad18 sgs1 rad14 rad18 rad52 sgs1 mec2 rad14 rad18 rad50 rad52 rad50EPP+ sgs1 CLN2oe bub3 mec2 rad14 rad18 rad50 rad52 mgt1 mlh1 rad50EPP+ sgs1 wt2 Stage2 Graphs for 674699 60 Cell Data for 674699 3D Structure for 674699 Basic Chemical Data for 674699
681761
    bub3 mec2 rad18 rad52 mgt1 mlh1 sgs1 wt2 CLN2oe bub3 mec2 rad14 rad18 rad50 rad52 mgt1 mlh1 sgs1 wt2 CLN2oe bub3 mec2 rad14 rad18 rad50 rad52 mgt1 mlh1 sgs1 wt2 Stage2 Graphs for 681761 60 Cell Data for 681761 3D Structure for 681761 Basic Chemical Data for 681761
682009
      bub3 rad18 rad50 mgt1 mlh1 sgs1 wt2 bub3 mec2 rad18 rad52 mgt1 mlh1 sgs1 wt2 Stage2 Graphs for 682009 60 Cell Data for 682009 3D Structure for 682009 Basic Chemical Data for 682009
683635
    CLN2oe bub3 rad18 rad50 rad52 mgt1 sgs1 wt2 CLN2oe bub3 mec2 rad14 rad18 rad50 rad52 mgt1 mlh1 sgs1 wt2 CLN2oe bub3 mec2 rad14 rad18 rad50 rad52 wt1 mgt1 mlh1 sgs1 wt2 Stage2 Graphs for 683635 60 Cell Data for 683635 3D Structure for 683635 Basic Chemical Data for 683635
684839
    CLN2oe bub3 mec2 rad52 wt2 CLN2oe bub3 mec2 rad14 rad18 rad50 rad52 wt1 mgt1 mlh1 sgs1 wt2 CLN2oe bub3 mec2 rad14 rad18 rad50 rad52 wt1 mgt1 mlh1 sgs1 wt2 Stage2 Graphs for 684839 60 Cell Data for 684839 3D Structure for 684839 Basic Chemical Data for 684839
687355
1H-[1,2,4]TRIAZOLO[1,2-A]
PYRIDAZINE-8-CARBOXYLIC ACID,
5-[(2,3,4,6-O-TETRAACETYL-
BETA-D-GLUCOPYRAN
      wt2 CLN2oe bub3 rad18 rad52 sgs1 wt2 Stage2 Graphs for 687355 60 Cell Data for 687355 3D Structure for 687355 Basic Chemical Data for 687355
688791
BENZOIC ACID, 4-[[(3,6-DIOXO-
1,4-CYCLOHEXADIENYLMETHYL]
AMINO]-2-HYDROXY-, METHYL ESTER
    CLN2oe rad14 rad18 rad50 rad52 mgt1 mlh1 rad50EPP+ sgs1 wt2 all all Stage2 Graphs for 688791 60 Cell Data for 688791 3D Structure for 688791 Basic Chemical Data for 688791

Previous 300 compounds that inhibit rad52

Email questions to: Susan Holbeck [holbecks@mail.nih.gov]