Abraham, I.M., Todman, M.G., Korach, K.S., Herbison, A.E., Critical in vivo roles for classical estrogen receptors in rapid estrogen actions on intracellular signaling in the mouse brain.Endocrinology 145:3055-3061, 2004[Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=14976146)
Korach, K.S., Emmen, J.M.A., Walker, V.R., Hewitt, S.C., Yates, M., Hall, J.M., Swope, D.L., Harrell, J.C., Couse, J.F., Update on animal models developed for analyses of estrogen receptor biological activity.J. Steroid Biochem Mol Biol 86: 387-391, 2003[Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=14623535)
Grummer, R, Hewitt, S.W., Traub, O., Korach, K.S., Winterhager, E., Different Regulatory Pathways of Endometrial Connexin Expression: Pre-implantation Hormonal Mediated Pathway Versus Embryo Implantation Initiated Pathway.Biol Reprod 71: 273-281, 2004[Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15028626)
Mueller, S.O., Simon, S., Chae, K., Metzler, M., Korach, K.S., Phytoestrogens and their human metabolites show distinct agonistic and antagonistic properties on estrogen receptor ERα and ERβ.Toxicol Sci. 80: 14-25, 2004.[Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15084758)
DeRoo, B.J., Hewitt, S.C., Korach, K.S., Estradiol regulates the thioredoxin antioxidant system in the mouse uterus.Endocrinology 145: 5485-5492, 2004.[Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15345672)
Pelzer, T., Loza, P-A.A., Hu, K., Bayer, B., Dienesch, C., Calvillo, L., Korach, K.S., Neyses, L., Ertl, G., Increased mortality and aggravation of heart failure in estrogen receptor-beta knockout mice after myocardial infarction.Circulation 111: 1492-1498, 2005.[Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15781739)
Hewitt, S.C., Collins, J., Grissom, S., Deroo, B., Korach, K.S., Global uterine genomics in vivo: microarray evaluation of the estrogen receptor alpha-growth factor cross-talk mechanism.Mol Endocrinol 19: 657-668, 2005.[Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15528273)
Nomura, M., Andersson, S., Korach, K.S., Gustafsson, J-A, Pfaff, D. W., Ogawa, S., Estrogen receptor-β gene disruption potentiates estrogen-inducible aggression but not sexual behavior in male mice.Neuroscience 130: 445-456, 2005.[Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15664701)
Couse, J.F., Yates, M.M., Sanford, R., Nyska, A., Nilson, J.H., Korach, K.S., Formation of cystic ovarian follicles associated with elevated luteinizing hormone requires estrogen receptor-beta.Endocrinology 145: 4693-4702, 2004.[Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15231698)
Mueller, S.O., Katzenellenbogen, J.A., Korach, K.S., Endogenous estrogen receptor beta is transcriptionally active in primary ovarian cells from estrogen receptor knockout mice. Steroids 69: 681-686, 2004.[Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15465114)
Kavaliers, M., Agmo, A., Choleris, E., Gustafsson, J-A., Korach, K.S., Muglia, L.J., Pfaff, D.W., Ogawa, S., Oxytocin and estrogen receptor alpha and beta knockout mice provide discriminably different odor cues in behavioral assays.Gene Brain Behav. 3: 189-195, 2004.[Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15307217)
Skavdahl, M., Steenbergen, C., Clark, J., Myers, P., Demianeko, T., Mao, L., Rockman, H.A., Korach, K.S., Murphy, E., Estrogen receptor-beta mediates male-female differences in the development of pressure overload hypertrophy. Am. J. Physiol.: Heart and Circulatory Physiology 288: H469-476, 2005.[Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15374829)
Ardelt, A.A., McCullough, L.D., Korach, K.S., Wang, W.M., Munzenmaier, D.H., Hurn, P.D., Estradiol regulates angiopoietin-1 mRNA expression through estrogen receptor-α in a rodent experimental stroke model.Stroke 36: 337-341, 2005.[Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15637314)
Gougelet, A., Bouclier,C., Marsaud, V., Maillard, S., Mueller, S.O., Korach, K.S., Renoir, J-M, Estrogen receptor a and b subtype expression and transactivation capacity are differentially affected by receptor-, hsp90- and immunophilin-ligands in human breast cancer cells.J. Steroid Biochem Mol Biol 94: 71-81, 2005.[Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15862952)
Jayachandran, M., Karnicki,K., Miller,R.S., Owen,W.G., Korach,K.S., Miller,V.M., Platelet Characteristics Change with Aging: Role of Estrogen Receptor beta.J Gerontol: Biol Sci. 60: 815-819, 2005[Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16079202)
Emmen, J.M.A., Couse, J.F., Elmore, S.A., Yates, M.M., Kissling, G.E., Korach, K.S., In vitro growth and ovulation of follicles from ovaries of estrogen receptor (ER)-α and ERβ null mice indicate a role for ERβ in follicular maturation.Endocrinology 146: 2817-2826, 2005.[Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15731357)
Hewitt, S.C., Deroo, B.J., Korach, K.S., Signal transduction: a new mediator for an old hormone?,Science 307: 1572-1573, 2005.[Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15761144)
Couse, J.F., Yates, M.M., Deroo, B.J., Korach, K.S., Estrogen receptor-beta is critical to granulosa cell differentiation and the ovulatory response to gonadotropins.Endocrinology 146: 3247-3262, 2005.[Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15831568)
Aoyama, H., Couse, J.F., Curtis, S.W., Korach, K.S., Haseman, J., Dixon, D. Upregulation of estrogen receptor expression in the uterus of ovariectomized B6C3F1 miceand Ishikawa cells treated with bromoethane. Tox Appl Pharmacol 209:226-235, 2005. [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15922381)
Tekmal, R.R., Liu, Y.G., Nair, H.B., Jones, J., Perla, R.P., Lubahn, D.B., Korach, K.S., Kirma, N., Estrogen receptor-α is required for mammary development and the induction of mammary hyperplasia and epigenetic alterations in aromatase transgenic mice.J. Steroid Biochem Mol Biol 95: 9-15, 2005.[Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15955696)
LeMay, C., Chu, K., Hu, M., Oretga, C.S., Simpson, E.R., Korach, K.S., Tsai, M-J., Mauvais-Jarvis, F., Estrogens protect pancreatic β-cells from apoptosis and prevent insulin-deficient diabetes mellitus in mice. Proc. Natl. Acad. Sci. 103: 9232-9237, 2006. [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=16754860&query_hl=3&itool=pubmed_docsum)
Szego, E.M., Barabas, K., Balog, J., Szilagyi, N., Korach, K.S., Juhasz, G., Abraham, I.M., Estrogen induces estrogen receptor alpha dependent CREB phosphorylation via MAPK pathway in basal forebrain cholinergic neurons in vivo. J. Neuroscience 26: 4104-4110, 2006 [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=16611827&query_hl=6&itool=pubmed_docsum)
Couse, J.F., Yates, M.M., Rodriguez, K.F., Johnson, J.A., Poireir, D., Korach, K.S., The intraovarian actions of estrogen receptor-α (ER-α) are necessary to repress the formation of morphological and functional leydig cells in the female gonad. Endocrinology 147: 3666-3678, 2006 [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=16627580&query_hl=9&itool=pubmed_docsum)
Yamamoto, Y., Moore, R., Hess, H.A., Guo, G.L., Gonzalez, F.J., Korach, K.S., Maronpot, R.R., Negishi, M., Estrogen receptor alpha mediates 17alpha-ethynylestradiol-causing hepatotoxicity. J. Biol Chem 281: 16625-16631, 2006 [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=16606610&query_hl=16&itool=pubmed_docsum)
Qiu, J., Bosch, M.A., Tobias, S.C., Krust, A., Graham, S.M., Murphy, S.J., Korach, K.S., Chambon, P., Scanlan, T.S., Ronnekleiv, O.K., Kelly, M.J., A G protein-coupled estrogen receptor is involved in hypothalamic control of energy homeostasis. J. Neuroscience 26: 5649-5655, 2006. [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=16723521&query_hl=12&itool=pubmed_docsum)
Lindzey, J., Jayes, F.L., Yates, M.M., Couse, J.F., Korach, K.S., The bi-modal effects of estradiol on gonadotropin synthesis and secretion in female mice are dependent on estrogen receptor-α (ER-α). J. Endocrinology 191: 309-317, 2006. [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=17065413&query_hl=19&itool=pubmed_docsum)
Choleris, E., Ogawa, S., Kavaliers, M.,Gustafsson, J.-Å, Korach, K.S., Muglia, L. J., Pfaff, D.W., Involvement of estrogen receptor alpha, beta and oxytocin in social discrimination: A detailed behavioral analysis with knockout female mice. Genes Brain Behav. 5:528-539, 2006. [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=17010099&query_hl=23&itool=pubmed_docsum)
Taniguchi, F., Couse, J.F., Rodriguez, K.F., Poirier, D., Korach, K.S., Estrogen receptor-α (ERa) mediates an intraovarian negative feedback loop on thecal cell androgen synthesis via modulation of Cyp17a1 expression. FASEB J. 21: 586-595, 2007 [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=17158782&query_hl=9&itool=pubmed_docsum)
O’Brien, J.E., Peterson, T.J., Tong, M.H., Lee, E-J., Pfaff, L.E., Hewitt, S.C., Korach, K.S., Weiss, J., Jameson, J.L., Estrogen induced proliferation of uterine epithelial cells is independent of estrogen receptor a binding to classical estrogen response elements. J. Biol Chem 281: 26683-26692, 2006 [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=16847062&query_hl=28&itool=pubmed_docsum)
Dahlman-Wright, K., Cavailles, V., Fuqua, S.A., Jordan, V.C., Katzenellenbogen, J.A., Korach, K.S., Maggi, A., Muramatsu, M., Parker, M.G., Gustafsson, J.A., International union of pharmacology. LXIV. Estrogen Receptors. Pharmacol Rev., 58: 773-781, 2006 [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=17132854&query_hl=31&itool=pubmed_docsum)
Henley, D.V., Lipson, N., Korach, K.S., Bloch, C.A., Prepubertal gynecomastia and lavender and tea tree oils. New Eng. J. Med. 356: 479-485, 2007 [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=17267908&query_hl=34&itool=pubmed_docsum)
Carey, M.A., Card, J.W., Bradbury, J.A., Moorman, M.P., Haykal-Coates, N., Gavett, S.H., Graves,J.P., Walker,V.R., Flake,G.P., Voltz, J.W., Zhu, D., Jacobs ,E.R., Dakhama, A., Larsen, G.L., Loader, J.L., Gelfand, E.W., Germolec, D.R., Korach, K.S., Zeldin,D.C., Spontaneous airway hyperresponsiveness in estrogen receptor-α deficient mice. Am J. Respiratory and Critical Care Medicine175: 126-135, 2007. [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=17095746&query_hl=37&itool=pubmed_docsum)
Santen, R.J., Yue, W., Boccinfuso, W., Korach, K.S., Wang, J-P., Rogan, E.G., Li, Y., Cavalieri, E., Russo, J., Devanesan, P., Verderame, M., Estradiol-induced carcinogenesis via formation of genotoxic metabolites, In: Advances in endocrine therapy of breast cancer.Ingle, J.N., Dowsett, M. (eds), Marcel Dekker, new York, 163-178, 2004.
Couse, J.F., Korach, K.S., Estrogen receptor-αlpha mediates the detrimental effects of neonatal diethylstilbestrol (DES) exposure in the murine reproductive tract.Toxicology 205: 55-63, 2004.[Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15458790)
Walker, V.R., Korach, K.S., Estrogen receptor knockout mice as a model for endocrine research.ILAR Journal 45: 455-461, 2004.[Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15454684)
Hewitt, S.C., Harrell, J.C., Korach, K.S., Lessons in Estrogen Biology from Knockout and Transgenic Animals,Ann. Rev. Physiol. 67: 285-308, 2005.[Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15709960)
Yue, W., Wang, J.P., Li, Y., Bocchinfuso, W.P., Korach, K.S., Devanesan, P.D., Rogan, E., Cavalieri, E., Santen, R. J., Tamoxifen versus aromatase inhibitors for breast cancer prevention.Clin Cancer Res. 11: 925s-930s, 2005.[Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15701888)
Henley, D.V., Korach, K.S., Endocrine-disrupting chemicals use distinct mechanisms of action to modulate endocrine system function. Endocrinology 147: 25s-32s, 2006.[Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16690802)
Couse, J.F., Hewitt, S.C., Korach, K.S., Steroid Receptors in the Ovary and Uterus, In: Knobil and Neill: Physiology of Reproduction 3rd Edition, Neill, J.D. (ed.), Academic Press, New York, New York, p 593-678, 2006.
Lindzey, J., Korach, K.S., Environmental agents and the reproductive system,In: DeGroot, L.J. Jameson, L.J. (eds.), Endocrinology, W.B. Saunders, Co., New York, New York, pp 2759-2777, 2006.