The Diabetic Kidney Disease Program funds basic research on the pathophysiology and pathogenesis of diabetic nephropathy, natural history studies, and clinical trials through the R01 mechanism. Fundamental research focuses on the molecular pathogenesis of extracellular matrix expansion and glomerulosclerosis, the role of the renin-angiotension system and growth factors, and the identification of treatments to prevent renal scarring.
Of special interest are studies to understand the mechanisms of progressive renal scarring, to identify genes that either protect people from or predispose them to diabetic nephropathy, and to identify early markers of increased risk for the disease.
For basic studies contact Dr. Chris Ketchum.
For clinical studies contact Dr. Catherine Meyers.