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Volume 7(3);  July 2005
Basic and Translational Investigations
Preclinical Experimental Therapeutics
Increased efficacy of an interleukin-12-secreting herpes simplex virus in a syngeneic intracranial murine glioma model
Elizabeth K. Hellums, James M. Markert, Jacqueline N. Parker, Bin He, Bernard Perbal, Bernard Roizman, Richard J. Whitley, Catherine P. Langford, Suman Bharara, and G. Yancey Gillespie
Neuro-oncol. 2005 July; 7(3): 213–224. doi: 10.1215/S1152851705000074.
PMCID: PMC1871915
Tumor Biology
Flavopiridol downregulates hypoxia-mediated hypoxia-inducible factor-1α expression in human glioma cells by a proteasome-independent pathway: Implications for in vivo therapy
Elizabeth W. Newcomb, M. Aktar Ali, Tona Schnee, Li Lan, Yevgeniy Lukyanov, Mary Fowkes, Douglas C. Miller, and David Zagzag
Neuro-oncol. 2005 July; 7(3): 225–235. doi: 10.1215/S1152851704000997.
PMCID: PMC1871916
Medical Neuro-Oncology
Pharmacological blockade of group II metabotropic glutamate receptors reduces the growth of glioma cells in vivo
Antonietta Arcella, Giulia Carpinelli, Giuseppe Battaglia, Mara D’Onofrio, Filippo Santoro, Richard Teke Ngomba, Valeria Bruno, Paola Casolini, Felice Giangaspero, and Ferdinando Nicoletti
Neuro-oncol. 2005 July; 7(3): 236–245. doi: 10.1215/S1152851704000961.
PMCID: PMC1871912
Clinical Investigations
Clinical Therapy Trials-Drug
Phase 2 trial of copper depletion and penicillamine as antiangiogenesis therapy of glioblastoma,
Steven Brem, Stuart A. Grossman, Kathryn A. Carson, Pamela New, Surasak Phuphanich, Jane B. Alavi, Tom Mikkelsen, and Joy D. Fisher
Neuro-oncol. 2005 July; 7(3): 246–253. doi: 10.1215/S1152851704000869.
PMCID: PMC1871917
Retrospective Clinical Studies
High failure rate in spinal ependymomas with long-term follow-up
Daniel R. Gomez, Brian T. Missett, William M. Wara, Kathleen R. Lamborn, Michael D. Prados, Susan Chang, Mitchel S. Berger, and Daphne A. Haas-Kogan
Neuro-oncol. 2005 July; 7(3): 254–259. doi: 10.1215/S1152851704001231.
PMCID: PMC1871913
Review
Tumor Biology
Chaperone proteins and brain tumors: Potential targets and possible therapeutics
Michael W. Graner and Darell D. Bigner
Neuro-oncol. 2005 July; 7(3): 260–277. doi: 10.1215/S1152851704001188.
PMCID: PMC1871914
Abstracts
Abstracts from the World Federation of Neuro-Oncology Second Quadrennial Meeting and the Sixth Meeting of the European Association for Neuro-Oncology: May 5–8, 2005, Edinburgh, United Kingdom
Neuro-oncol. 2005 July; 7(3): 279–402. doi: 10.1215/ S1152851705200388.
PMCID: PMC1871910
Society News and Announcements
SOCIETY NEWS AND ANNOUNCEMENTS
Neuro-oncol. 2005 July; 7(3): 421–422. doi: 10.1215/S1152851705200170.
PMCID: PMC1871911
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