Administrative Supplements to On-Going Erythroid Cell Research : NIDDK

Administrative Supplements to On-Going Erythroid Cell Research


The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) invites NIDDK-funded investigators to submit supplement requests to bolster their research activities in the study of expressed genes in erythroid cells. The supplement program will support characterization of expressed erythroid molecular biological components and creation of reagents useful for the study of erythroid cell lineages. Components include genes that are expressed in erythroid cells, either during development (i.e., embryonic, fetal liver, and adult stages) or during differentiation (i.e., committed CFU-E, pronormoblast, orthochromatophilic erythroblast, polychromatophilic erythroblast, reticulocyte stages), transcriptional regulatory components and the proteins that are translated in erythroid cells, potentially with post-translational modification or subcellular localizations that are unique to erythroid cells. The work proposed must be within the scope of the research recommended by peer review.


Only Principal Investigators of NIDDK-funded research grants may request supplemental funds. The PI must have an active R01, P01, R21, K award, or other such NIDDK-funded grant, with at least one year remaining at the time of anticipated funding date of September 1, 2003. The proposed research must fall within the scope of the parent grant and must be a logical extension of the goals and objectives, but should not be sufficiently different to constitute new research or program expansion.


All funding will be in the form of administrative supplements to existing NIDDK-funded research grants. The cost of a supplemental request is limited to a maximum of $70,000 (direct costs) for one year.


All applications must contain the following:

  • A cover letter listing the eligible parent grant, signed by the Principal Investigator and Administrative Official from the sponsoring institution.
  • A biosketch for the PI and any key personnel
  • Documentation of active research grant funding
  • A research plan, not to exceed 5 typed pages, that should include the following:
    • Introduction, not to exceed 1 typed page. The introduction to the supplemental application should provide an overall description of the nature of the supplement and how it will influence the specific aims, research design, and methods of the current grant.
    • Research Plan. The research plan should include sufficient information needed for evaluation of the supplement request, independent of any other document. Be specific and informative and avoid redundancies. There is no Form Page for the Research Plan. Organize Items a-d of the Research Plan to answer the following questions:

      1. What do you intend to do?
      2. Why is the work important?
      3. What has already been done?
      4. How are you going to do the work?
      5. How does the supplement enhance the work of the funded project?

Applications (1 original plus 5 copies) should be sent to:

David Badman, Ph.D.
Hematology Program Director
6707 Democracy Blvd., Rm. 621
Bethesda, MD 20892-5458
Phone: 301-594-7712

Applications must be received by June 15, 2003. Budget start dates should be calculated based on a funding start of September 1, 2003.


NIDDK will consider supplement requests from all eligible applicants. Requests will be evaluated according to the following criteria:

  • Evidence of prior ability to work with erythroid molecular biological components and the development of related reagents.
  • Evidence that the proposed research falls within the scope of the parent grant and is a logical extension of its goals and objectives.
  • Justification of the requested budget.

Supplement requests will be reviewed by a committee of NIDDK program staff. Award decisions will be based upon the criteria provided above, the availability of funds, and NIDDK programmatic priorities and balance.


NIDDK-funded investigators who are interested in applying for a supplement request are encouraged to contact

David Badman, Ph.D.
Hematology Program Director
6707 Democracy Blvd., Rm. 621
Bethesda, MD 20892-5458
Phone: 301-594-7712


Terry Rogers Bishop, Ph.D.
Hematology Genomics Program Director
6707 Democracy Blvd., Rm. 619
Bethesda, MD 20892-5458
Phone: 301-594-7726

Page last updated: November 25, 2008

General inquiries may be addressed to: Office of Communications & Public Liaison
Building 31. Rm 9A06
31 Center Drive, MSC 2560
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