| | Education Analyzing ChIP-chip Data Using Bioconductor Joern Toedling and Wolfgang Huber PLoS Comput Biol. 2008 November; 4(11): e1000227. Published online 2008 November 28. doi: 10.1371/journal.pcbi.1000227.PMCID: PMC2582686 Review Differentiating Protein-Coding and Noncoding RNA: Challenges and Ambiguities Marcel E. Dinger, Ken C. Pang, Tim R. Mercer, and John S. Mattick PLoS Comput Biol. 2008 November; 4(11): e1000176. Published online 2008 November 28. doi: 10.1371/journal.pcbi.1000176.PMCID: PMC2518207 Research Articles Facilitated Variation: How Evolution Learns from Past Environments To Generalize to New Environments Merav Parter, Nadav Kashtan, and Uri Alon PLoS Comput Biol. 2008 November; 4(11): e1000206. Published online 2008 November 7. doi: 10.1371/journal.pcbi.1000206.PMCID: PMC2563028 A Hierarchy of Time-Scales and the Brain Stefan J. Kiebel, Jean Daunizeau, and Karl J. Friston PLoS Comput Biol. 2008 November; 4(11): e1000209. Published online 2008 November 14. doi: 10.1371/journal.pcbi.1000209.PMCID: PMC2568860 Hierarchical Models in the Brain Karl Friston PLoS Comput Biol. 2008 November; 4(11): e1000211. Published online 2008 November 7. doi: 10.1371/journal.pcbi.1000211.PMCID: PMC2570625 A Model of Brain Circulation and Metabolism: NIRS Signal Changes
during Physiological Challenges Murad Banaji, Alfred Mallet, Clare E. Elwell, Peter Nicholls, and Chris E. Cooper PLoS Comput Biol. 2008 November; 4(11): e1000212. Published online 2008 November 7. doi: 10.1371/journal.pcbi.1000212.PMCID: PMC2573000 Transmembrane Topology and Signal Peptide Prediction Using Dynamic Bayesian Networks Sheila M. Reynolds, Lukas Käll, Michael E. Riffle, Jeff A. Bilmes, and William Stafford Noble PLoS Comput Biol. 2008 November; 4(11): e1000213. Published online 2008 November 7. doi: 10.1371/journal.pcbi.1000213.PMCID: PMC2570248 Evolutionary Modeling of Rate Shifts Reveals Specificity Determinants in HIV-1 Subtypes Osnat Penn, Adi Stern, Nimrod D. Rubinstein, Julien Dutheil, Eran Bacharach, Nicolas Galtier, and Tal Pupko PLoS Comput Biol. 2008 November; 4(11): e1000214. Published online 2008 November 7. doi: 10.1371/journal.pcbi.1000214.PMCID: PMC2566816 Distinct Modes of Regulation by Chromatin Encoded through Nucleosome Positioning Signals Yair Field, Noam Kaplan, Yvonne Fondufe-Mittendorf, Irene K. Moore, Eilon Sharon, Yaniv Lubling, Jonathan Widom, and Eran Segal PLoS Comput Biol. 2008 November; 4(11): e1000216. Published online 2008 November 7. doi: 10.1371/journal.pcbi.1000216.PMCID: PMC2570626 Inferring Pathway Activity toward Precise Disease Classification Eunjung Lee, Han-Yu Chuang, Jong-Won Kim, Trey Ideker, and Doheon Lee PLoS Comput Biol. 2008 November; 4(11): e1000217. Published online 2008 November 7. doi: 10.1371/journal.pcbi.1000217.PMCID: PMC2563693 Genome-Wide Analysis of Human Disease Alleles Reveals That Their Locations Are Correlated in Paralogous Proteins Mark Yandell, Barry Moore, Fidel Salas, Chris Mungall, Andrew MacBride, Charles White, and Martin G. Reese PLoS Comput Biol. 2008 November; 4(11): e1000218. Published online 2008 November 7. doi: 10.1371/journal.pcbi.1000218.PMCID: PMC2565504 A Low Dimensional Description of Globally Coupled Heterogeneous Neural Networks of Excitatory and Inhibitory Neurons Roxana A. Stefanescu and Viktor K. Jirsa PLoS Comput Biol. 2008 November; 4(11): e1000219. Published online 2008 November 14. doi: 10.1371/journal.pcbi.1000219.PMCID: PMC2574034 Emergence of Functional Hierarchy in a Multiple Timescale Neural
Network Model: A Humanoid Robot Experiment Yuichi Yamashita and Jun Tani PLoS Comput Biol. 2008 November; 4(11): e1000220. Published online 2008 November 7. doi: 10.1371/journal.pcbi.1000220.PMCID: PMC2570613 Polar or Apolar—The Role of Polarity for Urea-Induced Protein Denaturation Martin C. Stumpe and Helmut Grubmüller PLoS Comput Biol. 2008 November; 4(11): e1000221. Published online 2008 November 14. doi: 10.1371/journal.pcbi.1000221.PMCID: PMC2570617 A Generic Mechanism of Emergence of Amyloid Protofilaments from Disordered Oligomeric Aggregates Stefan Auer, Filip Meersman, Christopher M. Dobson, and Michele Vendruscolo PLoS Comput Biol. 2008 November; 4(11): e1000222. Published online 2008 November 14. doi: 10.1371/journal.pcbi.1000222.PMCID: PMC2572140 Quantification of Local Morphodynamics and Local GTPase Activity by Edge Evolution Tracking Yuki Tsukada, Kazuhiro Aoki, Takeshi Nakamura, Yuichi Sakumura, Michiyuki Matsuda, and Shin Ishii PLoS Comput Biol. 2008 November; 4(11): e1000223. Published online 2008 November 14. doi: 10.1371/journal.pcbi.1000223.PMCID: PMC2573959 A Predictive Model of the Oxygen and Heme Regulatory Network in Yeast Anshul Kundaje, Xiantong Xin, Changgui Lan, Steve Lianoglou, Mei Zhou, Li Zhang, and Christina Leslie PLoS Comput Biol. 2008 November; 4(11): e1000224. Published online 2008 November 14. doi: 10.1371/journal.pcbi.1000224.PMCID: PMC2573020 Phylogenetic Dependency Networks: Inferring Patterns of CTL Escape and Codon Covariation in HIV-1 Gag Jonathan M. Carlson, Zabrina L. Brumme, Christine M. Rousseau, Chanson J. Brumme, Philippa Matthews, Carl Kadie, James I. Mullins, Bruce D. Walker, P. Richard Harrigan, Philip J. R. Goulder, and David Heckerman PLoS Comput Biol. 2008 November; 4(11): e1000225. Published online 2008 November 21. doi: 10.1371/journal.pcbi.1000225.PMCID: PMC2579584 Neutrality and Robustness in Evo-Devo: Emergence of Lateral Inhibition Andreea Munteanu and Ricard V. Solé PLoS Comput Biol. 2008 November; 4(11): e1000226. Published online 2008 November 21. doi: 10.1371/journal.pcbi.1000226.PMCID: PMC2577890 Order-Based Representation in Random Networks of Cortical Neurons Goded Shahaf, Danny Eytan, Asaf Gal, Einat Kermany, Vladimir Lyakhov, Christoph Zrenner, and Shimon Marom PLoS Comput Biol. 2008 November; 4(11): e1000228. Published online 2008 November 21. doi: 10.1371/journal.pcbi.1000228.PMCID: PMC2580731 Behavioral Sequence Analysis Reveals a Novel Role for
ß2* Nicotinic Receptors in Exploration Nicolas Maubourguet, Annick Lesne, Jean-Pierre Changeux, Uwe Maskos, and Philippe Faure PLoS Comput Biol. 2008 November; 4(11): e1000229. Published online 2008 November 21. doi: 10.1371/journal.pcbi.1000229.PMCID: PMC2581917 Optimal Learning Rules for Discrete Synapses Adam B. Barrett and M. C. W. van Rossum PLoS Comput Biol. 2008 November; 4(11): e1000230. Published online 2008 November 28. doi: 10.1371/journal.pcbi.1000230.PMCID: PMC2580035 Structural and Thermodynamic Approach to Peptide Immunogenicity Carlos J. Camacho, Yasuhiro Katsumata, and Dana P. Ascherman PLoS Comput Biol. 2008 November; 4(11): e1000231. Published online 2008 November 21. doi: 10.1371/journal.pcbi.1000231.PMCID: PMC2577884 Age-Dependent Evolution of the Yeast Protein Interaction Network Suggests a Limited Role of Gene Duplication and Divergence Wan Kyu Kim and Edward M. Marcotte PLoS Comput Biol. 2008 November; 4(11): e1000232. Published online 2008 November 28. doi: 10.1371/journal.pcbi.1000232.PMCID: PMC2583957 PSICIC: Noise and Asymmetry in Bacterial Division Revealed by Computational Image Analysis at Sub-Pixel Resolution Jonathan M. Guberman, Allison Fay, Jonathan Dworkin, Ned S. Wingreen, and Zemer Gitai PLoS Comput Biol. 2008 November; 4(11): e1000233. Published online 2008 November 28. doi: 10.1371/journal.pcbi.1000233.PMCID: PMC2581597 A Methodological Framework for the Reconstruction of Contiguous Regions of Ancestral Genomes and Its Application to Mammalian Genomes Cedric Chauve and Eric Tannier PLoS Comput Biol. 2008 November; 4(11): e1000234. Published online 2008 November 28. doi: 10.1371/journal.pcbi.1000234.PMCID: PMC2580819 Multistable Decision Switches for Flexible Control of Epigenetic Differentiation Raúl Guantes and Juan F. Poyatos PLoS Comput Biol. 2008 November; 4(11): e1000235. Published online 2008 November 28. doi: 10.1371/journal.pcbi.1000235.PMCID: PMC2580821 Dynamic Changes in Protein Functional Linkage Networks Revealed by Integration with Gene Expression Data Shubhada R. Hegde, Palanisamy Manimaran, and Shekhar C. Mande PLoS Comput Biol. 2008 November; 4(11): e1000237. Published online 2008 November 28. doi: 10.1371/journal.pcbi.1000237.PMCID: PMC2580820 Corrections Correction: Similarity Queries for Temporal Toxicogenomic Expression Profiles Adam A. Smith, Aaron Vollrath, Christopher A. Bradfield, and Mark Craven PLoS Comput Biol. 2008 November; 4(11): 10.1371/annotation/48ea9acf-4422-4792-b9a6-565de3e64f60. Published online 2008 November 25. doi: 10.1371/annotation/48ea9acf-4422-4792-b9a6-565de3e64f60.PMCID: PMC2597899 Corrects: Adam A. Smith, et al. Similarity Queries for Temporal Toxicogenomic Expression Profiles. PLoS Comput Biol. 2008 July; 4(7): e1000116. Correction: The Rough Guide to In Silico Function Prediction, or How To Use Sequence and Structure Information To Predict Protein Function Marco Punta and Yanay Ofran PLoS Comput Biol. 2008 November; 4(11): 10.1371/annotation/3d8d748f-d1be-4ba9-84b3-23d2a582338b. Published online 2008 November 10. doi: 10.1371/annotation/3d8d748f-d1be-4ba9-84b3-23d2a582338b.PMCID: PMC2583278 Corrects: Marco Punta, et al. The Rough Guide to In Silico Function Prediction, or How To Use Sequence and Structure Information To Predict Protein Function. PLoS Comput Biol. 2008 October; 4(10): e1000160. |