| | Perspectives From Bytes to Bedside: Data Integration and Computational Biology for Translational Cancer Research Jomol P Mathew, Barry S Taylor, Gary D Bader, Saiju Pyarajan, Marco Antoniotti, Arul M Chinnaiyan, Chris Sander, Steven J Burakoff, and Bud Mishra PLoS Comput Biol. 2007 February; 3(2): e12. Published online 2007 February 23. doi: 10.1371/journal.pcbi.0030012.PMCID: PMC1808026 Research Articles Robustness Can Evolve Gradually in Complex Regulatory Gene Networks with Varying Topology Stefano Ciliberti, Olivier C Martin, and Andreas Wagner PLoS Comput Biol. 2007 February; 3(2): e15. Published online 2007 February 2. doi: 10.1371/journal.pcbi.0030015.PMCID: PMC1794322 Automatic Extraction of Protein Point Mutations Using a Graph Bigram Association Lawrence C Lee, Florence Horn, and Fred E Cohen PLoS Comput Biol. 2007 February; 3(2): e16. Published online 2007 February 2. doi: 10.1371/journal.pcbi.0030016.PMCID: PMC1794323 Efficiency and Cost of Economical Brain Functional Networks Sophie Achard and Ed Bullmore PLoS Comput Biol. 2007 February; 3(2): e17. Published online 2007 February 2. doi: 10.1371/journal.pcbi.0030017.PMCID: PMC1794324 Improving the Caenorhabditis elegans Genome Annotation Using Machine Learning Gunnar Rätsch, Sören Sonnenburg, Jagan Srinivasan, Hanh Witte, Klaus-R Müller, Ralf-J Sommer, and Bernhard Schölkopf PLoS Comput Biol. 2007 February; 3(2): e20. Prepublished online 2006 December 21. Published online 2007 February 23. doi: 10.1371/journal.pcbi.0030020.PMCID: PMC1808025 Mechanochemical Coupling in the Myosin Motor Domain. I. Insights from Equilibrium Active-Site Simulations Haibo Yu, Liang Ma, Yang Yang, and Qiang Cui PLoS Comput Biol. 2007 February; 3(2): e21. Prepublished online 2006 December 21. Published online 2007 February 9. doi: 10.1371/journal.pcbi.0030021.PMCID: PMC1796662 Deprotonation by Dehydration: The Origin of Ammonium Sensing in the AmtB Channel David L Bostick and Charles L. Brooks III PLoS Comput Biol. 2007 February; 3(2): e22. Prepublished online 2006 December 21. Published online 2007 February 9. doi: 10.1371/journal.pcbi.0030022.PMCID: PMC1796661 Mechanochemical Coupling in the Myosin Motor Domain. II. Analysis of Critical Residues Haibo Yu, Liang Ma, Yang Yang, and Qiang Cui PLoS Comput Biol. 2007 February; 3(2): e23. Prepublished online 2006 December 22. Published online 2007 February 16. doi: 10.1371/journal.pcbi.0030023.PMCID: PMC1800309 Specificity and Evolvability in Eukaryotic Protein Interaction Networks Pedro Beltrao and Luis Serrano PLoS Comput Biol. 2007 February; 3(2): e25. Prepublished online 2006 December 28. Published online 2007 February 16. doi: 10.1371/journal.pcbi.0030025.PMCID: PMC1797819 Functional Impact of Missense Variants in BRCA1 Predicted by Supervised Learning Rachel Karchin, Alvaro N. A Monteiro, Sean V Tavtigian, Marcelo A Carvalho, and Andrej Sali PLoS Comput Biol. 2007 February; 3(2): e26. Prepublished online 2006 December 28. Published online 2007 February 16. doi: 10.1371/journal.pcbi.0030026.PMCID: PMC1797820 Synonymous Substitution Rates Predict HIV Disease Progression as a Result of Underlying Replication Dynamics Philippe Lemey, Sergei L Kosakovsky Pond, Alexei J Drummond, Oliver G Pybus, Beth Shapiro, Helena Barroso, Nuno Taveira, and Andrew Rambaut PLoS Comput Biol. 2007 February; 3(2): e29. Prepublished online 2007 January 2. Published online 2007 February 23. doi: 10.1371/journal.pcbi.0030029.PMCID: PMC1797821 Unsupervised Learning of Visual Features through Spike Timing Dependent Plasticity Timothée Masquelier and Simon J Thorpe PLoS Comput Biol. 2007 February; 3(2): e31. Prepublished online 2007 January 2. Published online 2007 February 16. doi: 10.1371/journal.pcbi.0030031.PMCID: PMC1797822 Repressor Dimerization in the Zebrafish Somitogenesis Clock Olivier Cinquin PLoS Comput Biol. 2007 February; 3(2): e32. Published online 2007 February 16. doi: 10.1371/journal.pcbi.0030032.PMCID: PMC1797823 Assessing the Nature of Lipid Raft Membranes Perttu S Niemelä, Samuli Ollila, Marja T Hyvönen, Mikko Karttunen, and Ilpo Vattulainen PLoS Comput Biol. 2007 February; 3(2): e34. Prepublished online 2007 January 5. Published online 2007 February 23. doi: 10.1371/journal.pcbi.0030034.PMCID: PMC1808021 Persistent Activity in Neural Networks with Dynamic Synapses Omri Barak and Misha Tsodyks PLoS Comput Biol. 2007 February; 3(2): e35. Prepublished online 2007 January 9. Published online 2007 February 23. doi: 10.1371/journal.pcbi.0030035.PMCID: PMC1808024 Corrections Correction: Inferring Loss-of-Heterozygosity from Unpaired Tumors Using High-Density Oligonucleotide SNP Arrays Rameen Beroukhim, Ming Lin, Yuhyun Park, Ke Hao, Xiaojun Zhao, Levi A Garraway, Edward A Fox, Ephraim P Hochberg, Ingo K Mellinghoff, Matthias D Hofer, Aurelien Descazeaud, Mark A Rubin, Matthew Meyerson, Wing Hung Wong, William R Sellers, and Cheng Li PLoS Comput Biol. 2007 February; 3(2): e40. Published online 2007 February 23. doi: 10.1371/journal.pcbi.0030040.PMCID: PMC1808013 Corrects: Rameen Beroukhim, et al. Inferring Loss-of-Heterozygosity from Unpaired Tumors Using High-Density Oligonucleotide SNP Arrays. PLoS Comput Biol. 2006 May; 2(5): e41. Correction: The Role of Compensatory Mutations in the Emergence of Drug Resistance Andreas Handel, Roland R Regoes, and Rustom Antia PLoS Comput Biol. 2007 February; 3(2): e46. Published online 2007 February 23. doi: 10.1371/journal.pcbi.0030046.PMCID: PMC1808010 Corrects: Andreas Handel, et al. The Role of Compensatory Mutations in the Emergence of Drug Resistance. PLoS Comput Biol. 2006 October; 2(10): e137. Correction: The Genome: An Outsider's View Carl Zimmer PLoS Comput Biol. 2007 February; 3(2): e47. Published online 2007 February 23. doi: 10.1371/journal.pcbi.0030047.PMCID: PMC1808015 Corrects: Carl Zimmer. The Genome: An Outsider's View. PLoS Comput Biol. 2006 December; 2(12): e156. |