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Volume 1(6);  November 2005
Message from ISCB
Bioinformatics Education—Perspectives and Challenges
Shoba Ranganathan
PLoS Comput Biol. 2005 November; 1(6): e52. Published online 2005 November 25. doi: 10.1371/journal.pcbi.0010052.
PMCID: PMC1289384
Perspectives
NIH Roadmap Interdisciplinary Research Initiatives
Michael F Huerta, Gregory K Farber, Elizabeth L Wilder, Dushanka V Kleinman, Patricia A Grady, David A Schwartz, and Lawrence A Tabak
PLoS Comput Biol. 2005 November; 1(6): e59. Published online 2005 November 25. doi: 10.1371/journal.pcbi.0010059.
PMCID: PMC1289386
Review
Quasispecies Made Simple
J. J Bull, Lauren Ancel Meyers, and Michael Lachmann
PLoS Comput Biol. 2005 November; 1(6): e61. Published online 2005 November 25. doi: 10.1371/journal.pcbi.0010061.
PMCID: PMC1289388
Research Articles
Use of Artificial Genomes in Assessing Methods for Atypical Gene Detection
Rajeev K Azad and Jeffrey G Lawrence
PLoS Comput Biol. 2005 November; 1(6): e56. Published online 2005 November 11. doi: 10.1371/journal.pcbi.0010056.
PMCID: PMC1282332
A Guild of 45 CRISPR-Associated (Cas) Protein Families and Multiple CRISPR/Cas Subtypes Exist in Prokaryotic Genomes
Daniel H Haft, Jeremy Selengut, Emmanuel F Mongodin, and Karen E Nelson
PLoS Comput Biol. 2005 November; 1(6): e60. Prepublished online 2005 October 6. Published online 2005 November 11. doi: 10.1371/journal.pcbi.0010060.
PMCID: PMC1282333
The Association of Tetrameric Acetylcholinesterase with ColQ Tail: A Block Normal Mode Analysis
Deqiang Zhang and J. Andrew McCammon
PLoS Comput Biol. 2005 November; 1(6): e62. Prepublished online 2005 October 19. Published online 2005 November 18. doi: 10.1371/journal.pcbi.0010062.
PMCID: PMC1285061
Stealth Proteins: In Silico Identification of a Novel Protein Family Rendering Bacterial Pathogens Invisible to Host Immune Defense
Peter Sperisen, Christoph D Schmid, Philipp Bucher, and Olav Zilian
PLoS Comput Biol. 2005 November; 1(6): e63. Published online 2005 November 18. doi: 10.1371/journal.pcbi.0010063.
PMCID: PMC1285062
Quantitative Analysis of Genetic and Neuronal Multi-Perturbation Experiments
Alon Kaufman, Alon Keinan, Isaac Meilijson, Martin Kupiec, and Eytan Ruppin
PLoS Comput Biol. 2005 November; 1(6): e64. Prepublished online 2005 October 26. Published online 2005 November 25. doi: 10.1371/journal.pcbi.0010064.
PMCID: PMC1289391
Allele-Specific Amplification in Cancer Revealed by SNP Array Analysis
Thomas LaFramboise, Barbara A Weir, Xiaojun Zhao, Rameen Beroukhim, Cheng Li, David Harrington, William R Sellers, and Matthew Meyerson
PLoS Comput Biol. 2005 November; 1(6): e65. Prepublished online 2005 October 28. Published online 2005 November 25. doi: 10.1371/journal.pcbi.0010065.
PMCID: PMC1289392
Refining Protein Subcellular Localization
Michelle S Scott, Sara J Calafell, David Y Thomas, and Michael T Hallett
PLoS Comput Biol. 2005 November; 1(6): e66. Published online 2005 November 25. doi: 10.1371/journal.pcbi.0010066.
PMCID: PMC1289393
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