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Volume 1(1); June 2005 Editorial Message from ISCB Perspectives Research Articles Ab Initio Prediction of Transcription Factor Targets Using Structural Knowledge PMCID: PMC1183507 Susceptibility to Superhelically Driven DNA Duplex Destabilization: A Highly Conserved Property of Yeast Replication Origins PMCID: PMC1183513 Improving the Precision of the Structure–Function Relationship by Considering Phylogenetic Context PMCID: PMC1183515 Extraction of Transcript Diversity from Scientific Literature PMCID: PMC1183516 The Genomic Pattern of tDNA Operon Expression in E. coli PMCID: PMC1183518 microRNA Target Predictions across Seven Drosophila Species and Comparison to Mammalian Targets PMCID: PMC1183519 | ||