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Editor-in-Chief Melissa Norton, MD
Biology Editor Penelope Webb, PhD
In-house Editor Andrea Bucceri
Welcome to BMC Molecular Biology published by BioMed Central
BMC Molecular Biology is an open access journal publishing original peer-reviewed research articles in all aspects of DNA and RNA in a cellular context, encompassing investigations of transcription, mRNA processing, translation, replication, recombination, mutation, and repair.
BMC Molecular Biology (ISSN 1471-2199) is indexed/tracked/covered by PubMed, MEDLINE, BIOSIS, CAS, Scopus, EMBASE, Thomson Reuters (ISI) and Google Scholar.
BMC Molecular Biology 2008, 9 :109
Chromatin boundary proteins protect genes from transcriptional interactions and this insulator activity can be screened for in the Drosophila S2 cell line, using a new assay that complements existing in vivo methods.
BMC Molecular Biology 2008, 9 :105
A new conserved sequence motif found upstream of several microRNAs in two species of nematode worm, and also upstream of two microRNAs in mice and humans, may play a role in microRNA sequence recognition or regulation.
BMC Molecular Biology 2008, 9 :96
Measurement of template quantity in real-time qPCR using standard curves is prone to error, and the novel linear regression of efficiency method that calculates the amplification efficiency at the onset of each reaction is more accurate.
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Research article
Identification of suitable internal control genes for expression studies in Coffea arabica under different experimental conditions Carla F Barsalobres-Cavallari, Fabio E Severino, Mirian P Maluf, Ivan G Maia BMC Molecular Biology 2009, 10 :1 (6 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Transcriptional Regulation of BRD7 Expression By Sp1 And c-Myc Huaying Liu, Ming Zhou, Xiaomin Luo, Liming Zhang, Zhaoxia Niu, Cong Peng, Jian Ma, Shuping Peng, Houde Zhou, Bo Xiang, Xiayu Li, Shufang Li, Jiajin He, Xiaoling Li, Guiyuan Li BMC Molecular Biology 2008, 9 :111 (27 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Upstream stimulatory factors are involved in the P1 promoter directed transcription of the AbetaH-J-J locus Alessia Finotti, Susan Treves, Francesco Zorzato, Roberto Gambari, Giordana Feriotto BMC Molecular Biology 2008, 9 :110 (16 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Methodology article
Analysis of chromatin boundary activity in Drosophila cells Mo Li, Vladimir E Belozerov, Haini N Cai BMC Molecular Biology 2008, 9 :109 (11 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Two evolutionarily conserved sequence elements for Peg3/Usp29 transcription Jeong Do Kim, Sungryul Yu, Jung Ha Choo, Joomyeong Kim BMC Molecular Biology 2008, 9 :108 (10 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Functionally related transcripts have common RNA motifs for specific RNA-binding proteins in trypanosomes
Griselda Noe, Javier G De Gaudenzi, Alberto C Frasch BMC Molecular Biology 2008, 9 :107 (8 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Factors acting on Mos1 transposition efficiency
Ludivine Sinzelle, Gwenhael Jegot, Benjamin Brillet, Florence Rouleux-Bonnin, Yves Bigot, Corinne Auge-Gouillou BMC Molecular Biology 2008, 9 :106 (26 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Identification of phylogenetically conserved sequence motifs in microRNA 5' flanking sites from C. elegans and C. briggsae Liisa Heikkinen, Suvi Asikainen, Garry Wong BMC Molecular Biology 2008, 9 :105 (26 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
The artiodactyl APOBEC3 innate immune repertoire shows evidence for a multi-functional domain organization that existed in the ancestor of placental mammals Rebecca S LaRue, Stef BMC Molecular Biology 2008, 9 :104 (18 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Identification of Importin 8 (IPO8) as the most accurate reference gene for the clinicopathological analysis of lung specimens Paul A Nguewa, Jackeline Agorreta, David Blanco, Maria Dolores Lozano, Javier Gomez-Roman, Blas A Sanchez, I BMC Molecular Biology 2008, 9 :103 (17 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
New genes of Xanthomonas citri subsp. citri involved in pathogenesis and adaptation revealed by a transposon-based mutant library Marcelo L Laia, Leandro M Moreira, Juliana Dezajacomo, Joice B Brigati, Cristiano B Ferreira, Maria IT Ferro, Ana CR Silva, Julio CF Oliveira, Jesus A Ferro BMC Microbiology 2009, 9 :12 (16 [Abstract ] [Provisional PDF ]
Methodology article
Statistical evaluation of methods for quantifying gene expression by autoradiography in histological sections Stanley E Lazic BMC Neuroscience 2009, 10 :5 (15 [Abstract ] [Provisional PDF ]
Research article
Genetic evaluation of relationship between mutations in rpoB and resistance of Mycobacterium tuberculosis to rifampin. Anna Zaczek, Anna Brzostek, Ewa Augustynowicz-Kopec, Zofia Zwolska, Jaroslaw Dziadek BMC Microbiology 2009, 9 :10 (15 [Abstract ] [Provisional PDF ]
Research article
Optical mapping of the Mycobacterium avium subspecies paratuberculosis genome Chia-wei Wu, Timothy M Schramm, Shiguo Zhou, David C Schwartz, Adel M Talaat BMC Genomics 2009, 10 :25 (15 [Abstract ] [Provisional PDF ]
Methodology article
Reliable transfer of transcriptional gene regulatory networks between taxonomically related organisms Jan Baumbach, Sven Rahmann, Andreas Tauch BMC Systems Biology 2009, 3 :8 (15 [Abstract ] [Provisional PDF ]
Research
Minor contribution of mutations at iniA codon 501 and embC-embA intergenic region in ethambutol-resistant clinical Mycobacterium tuberculosis isolates in Kuwait Al-Anoud Jaber, Suhail Ahmad, Eiman Mokaddas Annals of Clinical Microbiology and Antimicrobials 2009, 8 :2 (15 [Abstract ] [Provisional PDF ]
Research
Mutagenesis identifies the critical amino acid residues of human endonuclease G involved in catalysis, magnesium coordination, and substrate specificity Shih-Lu Wu, Chia-Cheng Li, Jaw-Chyun Chen, Yi-Jin Chen, Ching-Ting Lin, Tin-Yun Ho, Chien-Yun Hsiang Journal of Biomedical Science 2009, 16 :6 (15 [Abstract ] [Provisional PDF ]
Research article
Correlation between MMPs and their inhibitors in breast cancer tumor tissue specimens and in cell lines with different metastatic potential Rita C S Figueira, Luciana R Gomes, Joao S Neto, Fabricio C Silva, Ismael D C G Silva, Mari C Sogayar BMC Cancer 2009, 9 :20 (14 [Abstract ] [Provisional PDF ]
Short report
Insulin-degrading enzyme is exported via an unconventional protein secretion pathway Ji Zhao, Lilin Li, Malcolm A Leissring Molecular Neurodegeneration 2009, 4 :4 (14 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Methodology article
Bacterial artificial chromosomes improve recombinant protein production in mammalian cells
Leander Blaas, Monica Musteanu, Robert Eferl, Anton Bauer, Emilio Casanova BMC Biotechnology 2009, 9 :3 (14 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
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